Send us a Message



 Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap)  (beta) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer) Overgo Probe Designer
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of purine nucleotide metabolic process
go back to main search page
Accession:GO:1900542 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of purine nucleotide metabolic process.
Synonyms:exact_synonym: regulation of purine nucleotide metabolism
 narrow_synonym: regulation of purine metabolic process;   regulation of purine metabolism


show annotations for term's descendants           Sort by:
regulation of purine nucleotide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LACC1 laccase domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:23,143,708...23,159,790
Ensembl chr11:23,141,133...23,159,649 		JBrowse link
negative regulation of ATP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 ISO RGD PMID:21325440 RGD:9685453 NCBI chr14:107,263,546...107,390,923
Ensembl chr14:107,263,449...107,389,010 		JBrowse link
G FLCN folliculin involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:61,029,186...61,045,400
Ensembl chr12:61,031,157...61,045,392 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:14,203,157...14,241,164
Ensembl chr10:14,203,160...14,241,196 		JBrowse link
G PID1 phosphotyrosine interaction domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:130,080,821...130,215,548
Ensembl chr15:130,075,143...130,332,698 		JBrowse link
negative regulation of ATP metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FIS1 fission, mitochondrial 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:8,938,250...8,942,102
Ensembl chr 3:8,937,453...8,946,955 		JBrowse link
G TSPO translocator protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:5,723,190...5,735,097
Ensembl chr 5:5,723,190...5,735,131 		JBrowse link
negative regulation of guanylate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HPCA hippocalcin ISO RGD PMID:15336960 RGD:9686438 NCBI chr 6:89,187,544...89,197,049
Ensembl chr 6:89,188,133...89,197,045 		JBrowse link
G RD3 RD3 regulator of GUCY2D involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:131,712,858...131,716,179
Ensembl chr 9:131,705,229...131,719,288 		JBrowse link
negative regulation of pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALDOB aldolase, fructose-bisphosphate B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:243,127,870...243,141,504
Ensembl chr 1:243,110,585...243,141,418 		JBrowse link
G TP53 tumor protein p53 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,644...52,953,818 		JBrowse link
positive regulation of ATP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCY10 adenylate cyclase 10 ISO RGD PMID:31172217 RGD:329403053 NCBI chr 4:83,103,768...83,205,015
Ensembl chr 4:83,098,290...83,205,454 		JBrowse link
G BCL2L1 BCL2 like 1 involved_in ISO PMID:23792689 CAFA PMID:23792689 RGD:12793033 NCBI chr17:35,366,139...35,415,798
Ensembl chr17:35,366,143...35,414,694 		JBrowse link
G ENO1 enolase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:69,385,879...69,401,664
Ensembl chr 6:69,385,879...69,401,151 		JBrowse link
G HNF1A HNF1 homeobox A ISO RGD PMID:20841353 RGD:150540305 NCBI chr14:40,868,819...40,888,322
Ensembl chr14:40,868,676...40,888,328 		JBrowse link
G IL4 interleukin 4 involved_in ISO (MGI:6304699|PMID:29061364) ARUK-UCL PMID:29061364 MGI:6304699 NCBI chr 2:134,986,817...134,994,365
Ensembl chr 2:134,986,817...134,994,365 		JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 involved_in ISO PMID:15459207 CAFA PMID:15459207 RGD:12793039 NCBI chr 1:164,381,892...164,469,313
Ensembl chr 1:164,381,845...164,471,226 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor ISO RGD PMID:22629444 RGD:7240532 NCBI chr 4:12,455,141...12,460,360
Ensembl chr 4:12,455,122...12,461,078 		JBrowse link
G NDUFC2 NADH:ubiquinone oxidoreductase subunit C2 ISO RGD PMID:26888427 RGD:11040458 NCBI chr 9:12,486,488...12,492,507
Ensembl chr 9:12,485,167...12,492,591 		JBrowse link
G PID1 phosphotyrosine interaction domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:130,080,821...130,215,548
Ensembl chr15:130,075,143...130,332,698 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha acts_upstream_of
involved_in		 ISO
IEA		 (PMID:31574452) ARUK-UCL
Ensembl		 PMID:31574452 GO_REF:0000107 NCBI chr 5:3,302,755...3,321,091
Ensembl chr 5:3,300,741...3,364,239 		JBrowse link
G PPARGC1A PPARG coactivator 1 alpha involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:17,841,844...18,527,953
Ensembl chr 8:17,841,844...17,946,992 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase ISO RGD PMID:24096089 RGD:10413842 NCBI chr 1:5,698,508...6,731,132
Ensembl chr 1:5,465,312...6,730,872 		JBrowse link
G SIRT1 sirtuin 1 involved_in IMP (PMID:24747689) AgBase PMID:24747689 NCBI chr14:71,091,167...71,126,351
Ensembl chr14:71,091,167...71,123,297 		JBrowse link
G SLC25A12 solute carrier family 25 member 12 ISO RGD PMID:19764902 RGD:13628741 NCBI chr15:77,895,935...78,021,930
Ensembl chr15:77,895,938...78,098,383 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 ISO RGD PMID:23590160 RGD:8694322 NCBI chr12:20,407,316...20,471,091
Ensembl chr12:20,407,233...20,472,992 		JBrowse link
G TAFAZZIN tafazzin, phospholipid-lysophospholipid transacylase ISO RGD PMID:20348225 RGD:13432160 NCBI chr  X:124,940,036...124,946,275
Ensembl chr  X:124,940,031...124,946,273 		JBrowse link
G TMSB4X thymosin beta 4 X-linked involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:9,649,516...9,651,662
Ensembl chr  X:9,650,179...9,651,661 		JBrowse link
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in ISO (MGI:5906931|PMID:28802038) ARUK-UCL PMID:28802038 MGI:5906931 NCBI chr 7:36,465,921...36,471,509
Ensembl chr 7:36,465,324...36,471,516 		JBrowse link
G VCP valosin containing protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:235,854,532...235,869,712
Ensembl chr 1:235,851,206...235,869,634 		JBrowse link
positive regulation of ATP metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BEND3 BEN domain containing 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:73,184,745...73,224,663
Ensembl chr 1:73,184,753...73,241,022 		JBrowse link
positive regulation of guanylate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA2B adenosine A2b receptor acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3794903|PMID:18340377) MGI
Ensembl		 PMID:18340377 GO_REF:0000107 MGI:3794903 NCBI chr12:59,431,834...59,449,701
Ensembl chr12:59,431,513...59,449,672 		JBrowse link
G GUCA1A guanylate cyclase activator 1A involved_in ISO
IBA		 (PMID:21873635) RGD
GO_Central		 PMID:12545196 PMID:21873635 RGD:1599357 NCBI chr 7:37,282,630...37,296,713
Ensembl chr 7:37,282,700...37,296,717 		JBrowse link
G NOS1 nitric oxide synthase 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:35,112,898...35,299,297
Ensembl chr14:35,113,184...35,295,944 		JBrowse link
G NOS3 nitric oxide synthase 3 involved_in IEA
IBA		 (PMID:21873635) Ensembl
GO_Central		 PMID:21873635 GO_REF:0000107 NCBI chr18:6,209,218...6,228,912
Ensembl chr18:6,209,158...6,228,943 		JBrowse link
positive regulation of pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TIGAR TP53 induced glycolysis regulatory phosphatase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:66,044,679...66,067,571
Ensembl chr 5:66,044,686...66,067,377 		JBrowse link
regulation of acetyl-CoA biosynthetic process from pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDK1 pyruvate dehydrogenase kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:78,608,394...78,650,958
Ensembl chr15:78,608,432...78,652,962 		JBrowse link
G PDK2 pyruvate dehydrogenase kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:26,274,562...26,295,787
Ensembl chr12:26,274,606...26,301,878 		JBrowse link
G PDK3 pyruvate dehydrogenase kinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:20,486,205...20,598,492
Ensembl chr  X:20,486,341...20,602,664 		JBrowse link
G PDK4 pyruvate dehydrogenase kinase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:75,246,956...75,260,134
Ensembl chr 9:75,246,002...75,260,134 		JBrowse link
regulation of acyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SNCA synuclein alpha acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3629421|PMID:16734431)
(MGI:3628986|PMID:16636270)		 MGI
Ensembl		 PMID:16636270 PMID:16734431 GO_REF:0000107 MGI:3628986 MGI:3629421 NCBI chr 8:129,247,724...129,388,307
Ensembl chr 8:129,248,819...129,271,128 		JBrowse link
regulation of ATP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SPHK2 sphingosine kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:53,982,911...53,986,779
Ensembl chr 6:53,979,012...53,986,768 		JBrowse link
regulation of ATP metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP5IF1 ATP synthase inhibitory factor subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:85,307,242...85,309,211
Ensembl chr 6:85,307,189...85,309,215 		JBrowse link
G FGD4 FYVE, RhoGEF and PH domain containing 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:41,571,054...41,636,058
Ensembl chr 5:41,570,282...41,636,028 		JBrowse link
regulation of guanylate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GUCA1A guanylate cyclase activator 1A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3052899|PMID:15336959) Ensembl
MGI		 PMID:15336959 GO_REF:0000107 MGI:3052899 NCBI chr 7:37,282,630...37,296,713
Ensembl chr 7:37,282,700...37,296,717 		JBrowse link
G GUCA1B guanylate cyclase activator 1B acts_upstream_of_or_within
involved_in		 ISO
IBA		 (MGI:3052899|PMID:15336959)
(PMID:21873635)		 MGI
GO_Central		 PMID:15336959 PMID:21873635 MGI:3052899 NCBI chr 7:37,297,901...37,311,158
Ensembl chr 7:37,297,908...37,310,170 		JBrowse link
regulation of mitochondrial ATP synthesis coupled proton transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANTKMT adenine nucleotide translocase lysine methyltransferase involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 3:41,057,727...41,059,309
Ensembl chr 3:41,057,649...41,062,032 		JBrowse link
G ATPSCKMT ATP synthase c subunit lysine N-methyltransferase involved_in IEA
IBA		 (PMID:21873635) Ensembl
GO_Central		 PMID:21873635 GO_REF:0000107 NCBI chr16:72,223,492...72,242,073
Ensembl chr16:72,223,534...72,242,064 		JBrowse link
G DNAJC30 DnaJ heat shock protein family (Hsp40) member C30 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:10,951,173...10,959,935
Ensembl chr 3:10,955,877...10,959,916 		JBrowse link
regulation of NAD metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MACROH2A1 macroH2A.1 histone involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:137,535,128...137,623,886
Ensembl chr 2:137,534,138...137,623,886 		JBrowse link
regulation of NADP metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HNF1A HNF1 homeobox A ISO RGD PMID:20841353 RGD:150540305 NCBI chr14:40,868,819...40,888,322
Ensembl chr14:40,868,676...40,888,328 		JBrowse link
G ME1 malic enzyme 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:82,799,878...82,989,895
Ensembl chr 1:82,799,684...82,991,085 		JBrowse link
G ME2 malic enzyme 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:100,419,404...100,475,778
Ensembl chr 1:100,419,760...100,476,733 		JBrowse link
regulation of pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSD11B1 hydroxysteroid 11-beta dehydrogenase 1 ISO RGD PMID:16234247 RGD:1625062 NCBI chr 9:133,231,451...133,278,396
Ensembl chr 9:133,231,451...133,278,396 		JBrowse link
G PGAM1 phosphoglycerate mutase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:108,822,782...108,832,818
Ensembl chr14:108,822,812...108,833,058 		JBrowse link
G TIGAR TP53 induced glycolysis regulatory phosphatase involved_in IEA
IBA		 (PMID:21873635) Ensembl
GO_Central		 PMID:21873635 GO_REF:0000107 NCBI chr 5:66,044,679...66,067,571
Ensembl chr 5:66,044,686...66,067,377 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17223
    metabolic process 10710
      small molecule metabolic process 1700
        regulation of small molecule metabolic process 376
          regulation of nucleotide metabolic process 54
            regulation of purine nucleotide metabolic process 52
              negative regulation of purine nucleotide metabolic process + 10
              positive regulation of purine nucleotide metabolic process + 25
              regulation of ATP metabolic process + 31
              regulation of NAD metabolic process + 1
              regulation of NADP metabolic process + 8
              regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway + 0
              regulation of purine nucleotide biosynthetic process + 38
              regulation of purine nucleotide catabolic process + 0
              regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA + 0
Path 2
Term Annotations click to browse term
  biological_process 17223
    cellular process 15352
      cellular metabolic process 6581
        heterocycle metabolic process 2744
          nucleobase-containing compound metabolic process 2588
            nucleobase-containing small molecule metabolic process 516
              nucleoside phosphate metabolic process 450
                nucleotide metabolic process 443
                  purine nucleotide metabolic process 385
                    regulation of purine nucleotide metabolic process 52
                      negative regulation of purine nucleotide metabolic process + 10
                      positive regulation of purine nucleotide metabolic process + 25
                      regulation of ATP metabolic process + 31
                      regulation of NAD metabolic process + 1
                      regulation of NADP metabolic process + 8
                      regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway + 0
                      regulation of purine nucleotide biosynthetic process + 38
                      regulation of purine nucleotide catabolic process + 0
                      regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA + 0
paths to the root