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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of purine nucleotide metabolic process
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Accession:GO:1900542 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of purine nucleotide metabolic process.
Synonyms:exact_synonym: regulation of purine nucleotide metabolism
 narrow_synonym: regulation of purine metabolic process;   regulation of purine metabolism


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regulation of purine nucleotide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lacc1 laccase domain containing 1 involved_in IMP (PMID:31978345) UniProt PMID:31978345 NCBI chr14:77,261,640...77,274,344
Ensembl chr14:77,261,640...77,274,344 		JBrowse link
negative regulation of ATP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 involved_in ISO RGD
GO_Central		 PMID:21325440 GO_REF:0000096 RGD:9685453 NCBI chr19:40,600,810...40,730,046
Ensembl chr19:40,600,810...40,730,046 		JBrowse link
G Mir675 microRNA 675 acts_upstream_of ISO (PMID:31574452) ARUK-UCL PMID:31574452 NCBI chr 7:142,130,801...142,130,884
Ensembl chr 7:142,130,801...142,130,884 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 involved_in ISO GO_Central GO_REF:0000119 NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819 		JBrowse link
G Pid1 phosphotyrosine interaction domain containing 1 involved_in ISO
IEA 		GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr 1:84,014,014...84,317,550
Ensembl chr 1:84,014,017...84,341,901 		JBrowse link
negative regulation of ATP metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fis1 fission, mitochondrial 1 involved_in IEA
ISO 		Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr 5:136,982,129...136,995,088
Ensembl chr 5:136,982,129...136,995,088 		JBrowse link
G Tspo translocator protein involved_in IMP (PMID:25470454) ParkinsonsUK-UCL PMID:25470454 NCBI chr15:83,447,774...83,458,404
Ensembl chr15:83,447,793...83,458,404 		JBrowse link
negative regulation of glycolytic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn3 actinin alpha 3 involved_in IMP (PMID:17828264) UniProt PMID:17828264 NCBI chr19:4,911,244...4,927,937
Ensembl chr19:4,911,244...4,927,937 		JBrowse link
G Cbfa2t3 CBFA2/RUNX1 translocation partner 3 involved_in ISS
ISO 		UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000119 NCBI chr 8:123,351,875...123,426,069
Ensembl chr 8:123,351,880...123,425,848 		JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 acts_upstream_of_or_within IMP (PMID:20176937) MGI PMID:20176937 NCBI chr10:59,785,497...59,787,592
Ensembl chr10:59,785,491...59,787,656 		JBrowse link
G Fbp1 fructose bisphosphatase 1 involved_in ISO
IEA
ISS 		GO_Central
Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 GO_REF:0000119 NCBI chr13:63,012,567...63,036,112
Ensembl chr13:63,012,567...63,036,096 		JBrowse link
G Flcn folliculin involved_in ISO
IEA 		GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr11:59,682,234...59,706,138
Ensembl chr11:59,682,234...59,700,842 		JBrowse link
G Git1 GIT ArfGAP 1 involved_in IMP (PMID:32460388) UniProt PMID:32460388 NCBI chr11:77,384,114...77,398,600
Ensembl chr11:77,384,388...77,398,612 		JBrowse link
G Hdac4 histone deacetylase 4 involved_in IMP (PMID:19109424) BHF-UCL PMID:19109424 NCBI chr 1:91,856,501...92,123,424
Ensembl chr 1:91,856,501...92,123,421 		JBrowse link
G Ier3 immediate early response 3 acts_upstream_of_or_within IMP (PMID:19096392) MGI PMID:19096392 NCBI chr17:36,132,605...36,133,803
Ensembl chr17:36,132,576...36,133,815 		JBrowse link
G Mtch2 mitochondrial carrier 2 acts_upstream_of_or_within IMP (PMID:26219591) MGI PMID:26219591 NCBI chr 2:90,677,434...90,697,154
Ensembl chr 2:90,677,499...90,697,154 		JBrowse link
G Myog myogenin involved_in ISO RGD
GO_Central		 PMID:10225962 GO_REF:0000096 RGD:9686132 NCBI chr 1:134,217,742...134,220,286
Ensembl chr 1:134,217,727...134,220,286 		JBrowse link
G Ncor1 nuclear receptor co-repressor 1 involved_in ISO GO_Central GO_REF:0000119 NCBI chr11:62,207,132...62,348,200
Ensembl chr11:62,207,252...62,349,367 		JBrowse link
G Nupr1 nuclear protein transcription regulator 1 involved_in ISO
IEA
ISS 		GO_Central
Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 GO_REF:0000119 NCBI chr 7:126,222,418...126,224,642
Ensembl chr 7:126,222,421...126,230,033 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha involved_in IEA
ISO 		Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr15:85,619,112...85,691,052
Ensembl chr15:85,619,184...85,687,020 		JBrowse link
G Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha involved_in ISO RGD
GO_Central		 PMID:22343369 GO_REF:0000096 RGD:7242186 NCBI chr 5:51,611,591...52,273,316
Ensembl chr 5:51,611,592...51,725,068 		JBrowse link
G Sik2 salt inducible kinase 2 involved_in IMP (PMID:21084751) MGI PMID:21084751 NCBI chr 9:50,800,944...50,920,432
Ensembl chr 9:50,804,101...50,920,373 		JBrowse link
G Sirt6 sirtuin 6 involved_in IMP
IEA
ISS
ISO 		(PMID:20141841), (PMID:23217706) CACAO
Ensembl
UniProt
GO_Central		 PMID:20141841 PMID:23217706 GO_REF:0000024 GO_REF:0000107 GO_REF:0000119 NCBI chr10:81,457,621...81,463,631
Ensembl chr10:81,457,619...81,463,631 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 acts_upstream_of_or_within IMP (PMID:22891351) MGI PMID:22891351 NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366 		JBrowse link
G Tigar Trp53 induced glycolysis regulatory phosphatase acts_upstream_of_or_within
involved_in 		IDA
IBA 		(PMID:20935145) MGI
GO_Central		 PMID:20935145 GO_REF:0000033 NCBI chr 6:127,062,079...127,086,564
Ensembl chr 6:127,062,079...127,086,520 		JBrowse link
G Trim63 tripartite motif-containing 63 involved_in ISO GO_Central GO_REF:0000119 NCBI chr 4:134,042,431...134,056,940
Ensembl chr 4:134,042,431...134,056,940 		JBrowse link
negative regulation of glycolytic process through fructose-6-phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpi1 glucose-6-phosphate isomerase 1 acts_upstream_of_or_within IGI (PMID:16155866) MGI PMID:16155866 NCBI chr 7:33,900,752...33,929,761
Ensembl chr 7:33,900,755...33,929,761 		JBrowse link
G Pfkfb1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 involved_in IMP
IGI 		(PMID:15331593)
(PMID:16155866) 		MGI PMID:15331593 PMID:16155866 NCBI chr  X:149,370,441...149,426,874
Ensembl chr  X:149,371,225...149,426,874 		JBrowse link
G Ppp2ca protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform involved_in IMP (PMID:32192773) MGI PMID:32192773 NCBI chr11:51,989,651...52,013,576
Ensembl chr11:51,989,508...52,018,605 		JBrowse link
G Prkaca protein kinase, cAMP dependent, catalytic, alpha involved_in IMP
IDA 		(PMID:16155866)
(PMID:23292513) 		MGI PMID:16155866 PMID:23292513 NCBI chr 8:84,699,607...84,723,073
Ensembl chr 8:84,699,622...84,723,072 		JBrowse link
G Slc4a1 solute carrier family 4 (anion exchanger), member 1 acts_upstream_of_or_within IMP (PMID:18698006) MGI PMID:18698006 NCBI chr11:102,239,646...102,256,107
Ensembl chr11:102,239,650...102,257,029 		JBrowse link
negative regulation of guanylate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hpca hippocalcin involved_in ISO RGD
GO_Central		 PMID:15336960 GO_REF:0000096 RGD:9686438 NCBI chr 4:129,005,363...129,019,712
Ensembl chr 4:129,005,363...129,015,829 		JBrowse link
G Rd3 retinal degeneration 3 involved_in IMP
ISO 		(PMID:27471269) UniProt
GO_Central		 PMID:27471269 GO_REF:0000119 NCBI chr 1:191,688,574...191,725,497
Ensembl chr 1:191,709,331...191,720,244 		JBrowse link
negative regulation of mitochondrial ATP synthesis coupled proton transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp5if1 ATP synthase inhibitory factor subunit 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr 4:132,257,870...132,262,746
Ensembl chr 4:132,257,866...132,260,970 		JBrowse link
negative regulation of pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldob aldolase B, fructose-bisphosphate involved_in ISO
IEA 		GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr 4:49,535,993...49,549,546
Ensembl chr 4:49,535,995...49,549,546 		JBrowse link
G Trp53 transformation related protein 53 involved_in ISO
IEA 		GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
positive regulation of ATP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy10 adenylate cyclase 10 involved_in ISO RGD
GO_Central		 PMID:31172217 GO_REF:0000096 RGD:329403053 NCBI chr 1:165,309,114...165,404,347
Ensembl chr 1:165,312,752...165,404,343 		JBrowse link
G Bcl2l1 BCL2-like 1 involved_in ISO GO_Central GO_REF:0000096 NCBI chr 2:152,600,652...152,673,632
Ensembl chr 2:152,622,588...152,673,648 		JBrowse link
G Eno1 enolase 1, alpha non-neuron involved_in ISO GO_Central GO_REF:0000119 NCBI chr 4:150,321,165...150,333,336
Ensembl chr 4:150,321,178...150,333,336
Ensembl chr18:150,321,178...150,333,336 		JBrowse link
G Eno1b enolase 1B, retrotransposed involved_in ISO GO_Central GO_REF:0000119 NCBI chr18:48,178,402...48,181,446
Ensembl chr18:48,178,402...48,181,479 		JBrowse link
G Hnf1a HNF1 homeobox A involved_in ISO
IEA 		RGD
GO_Central
Ensembl		 PMID:20841353 GO_REF:0000096 GO_REF:0000107 RGD:150540305 NCBI chr 5:115,087,039...115,109,121
Ensembl chr 5:115,087,039...115,109,153 		JBrowse link
G Il4 interleukin 4 involved_in IDA (PMID:29061364) ARUK-UCL PMID:29061364 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496 		JBrowse link
G Map2k1 mitogen-activated protein kinase kinase 1 involved_in ISO
IEA 		GO_Central
Ensembl		 GO_REF:0000096 GO_REF:0000107 NCBI chr 9:64,093,066...64,160,887
Ensembl chr 9:64,093,052...64,160,913 		JBrowse link
G Myc myelocytomatosis oncogene involved_in ISO RGD
GO_Central		 PMID:22629444 GO_REF:0000096 RGD:7240532 NCBI chr15:61,857,190...61,862,210
Ensembl chr15:61,857,240...61,862,223 		JBrowse link
G Ndufc2 NADH:ubiquinone oxidoreductase subunit C2 involved_in ISO
IEA 		RGD
Ensembl
GO_Central		 PMID:26888427 GO_REF:0000096 GO_REF:0000107 RGD:11040458 NCBI chr 7:97,049,210...97,057,007
Ensembl chr 7:97,049,210...97,057,009 		JBrowse link
G Pid1 phosphotyrosine interaction domain containing 1 involved_in IMP (PMID:21080215) BHF-UCL PMID:21080215 NCBI chr 1:84,014,014...84,317,550
Ensembl chr 1:84,014,017...84,341,901 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha acts_upstream_of ISO
IEA 		GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr15:85,619,112...85,691,052
Ensembl chr15:85,619,184...85,687,020 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO
IEA 		RGD
Ensembl
GO_Central		 PMID:24096089 GO_REF:0000096 GO_REF:0000107 RGD:10413842 NCBI chr17:11,059,227...12,282,257
Ensembl chr17:11,059,271...12,282,248 		JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (PMID:24747689) AgBase PMID:24747689 NCBI chr10:63,154,784...63,174,814
Ensembl chr10:63,154,784...63,217,483 		JBrowse link
G Slc25a12 solute carrier family 25 (mitochondrial carrier, Aralar), member 12 involved_in ISO RGD
GO_Central		 PMID:19764902 GO_REF:0000096 RGD:13628741 NCBI chr 2:71,104,614...71,198,125
Ensembl chr 2:71,101,407...71,198,093 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 involved_in ISO
IEA 		RGD
Ensembl
GO_Central		 PMID:23590160 GO_REF:0000096 GO_REF:0000107 RGD:8694322 NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366 		JBrowse link
G Tafazzin tafazzin, phospholipid-lysophospholipid transacylase involved_in ISO RGD
GO_Central		 PMID:20348225 GO_REF:0000096 RGD:13432160 NCBI chr  X:73,325,498...73,340,182
Ensembl chr  X:73,325,518...73,333,757 		JBrowse link
G Tmsb4x thymosin, beta 4, X chromosome involved_in ISO GO_Central GO_REF:0000119 NCBI chr  X:165,990,089...165,996,475
Ensembl chr  X:165,990,089...165,992,311 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in IMP (PMID:28802038) ARUK-UCL PMID:28802038 NCBI chr17:48,653,429...48,659,304
Ensembl chr17:48,653,429...48,661,175 		JBrowse link
G Vcp valosin containing protein involved_in ISO
IEA 		GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr 4:42,979,964...43,000,507
Ensembl chr 4:42,979,963...43,000,507 		JBrowse link
positive regulation of ATP metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bend3 BEN domain containing 3 involved_in ISS
IEA
ISO 		UniProt
Ensembl
GO_Central		 GO_REF:0000024 GO_REF:0000107 GO_REF:0000119 NCBI chr10:43,355,130...43,391,413
Ensembl chr10:43,354,827...43,391,392 		JBrowse link
positive regulation of glycolytic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein involved_in ISO GO_Central GO_REF:0000119 NCBI chr16:84,751,236...84,972,187
Ensembl chr16:84,746,573...84,970,654 		JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator acts_upstream_of IEA
ISO 		Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr 3:95,341,674...95,404,551
Ensembl chr 3:95,341,699...95,404,551 		JBrowse link
G Esrrb estrogen related receptor, beta involved_in ISO GO_Central GO_REF:0000096 NCBI chr12:86,407,891...86,568,402
Ensembl chr12:86,407,891...86,568,402 		JBrowse link
G Gapdhs glyceraldehyde-3-phosphate dehydrogenase, spermatogenic involved_in TAS (PMID:15546993) UniProt PMID:15546993 NCBI chr 7:30,429,204...30,443,106
Ensembl chr 7:30,429,200...30,443,106 		JBrowse link
G Gck glucokinase involved_in ISO RGD
GO_Central		 PMID:17553851 GO_REF:0000096 RGD:2301905 NCBI chr11:5,850,816...5,900,081
Ensembl chr11:5,850,820...5,900,081 		JBrowse link
G Gpd1 glycerol-3-phosphate dehydrogenase 1 (soluble) acts_upstream_of_or_within IMP (PMID:11147825) MGI PMID:11147825 NCBI chr15:99,615,468...99,622,895
Ensembl chr15:99,615,396...99,622,886 		JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit acts_upstream_of IEA
ISO 		Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr12:73,948,186...73,994,304
Ensembl chr12:73,948,149...73,994,304 		JBrowse link
G Htr2a 5-hydroxytryptamine (serotonin) receptor 2A acts_upstream_of_or_within IMP (PMID:17408640) MGI PMID:17408640 NCBI chr14:74,878,314...74,944,299
Ensembl chr14:74,878,280...74,946,934 		JBrowse link
G Ifng interferon gamma involved_in IDA (PMID:29061364) ARUK-UCL PMID:29061364 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797 		JBrowse link
G Igf1 insulin-like growth factor 1 involved_in ISO
IEA 		GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr10:87,694,127...87,772,909
Ensembl chr10:87,694,127...87,772,904 		JBrowse link
G Ins1 insulin I involved_in ISO GO_Central GO_REF:0000119 NCBI chr19:52,252,735...52,253,453
Ensembl chr19:52,252,735...52,253,914 		JBrowse link
G Ins2 insulin II involved_in ISO GO_Central GO_REF:0000119 NCBI chr 7:142,232,393...142,233,463
Ensembl chr 7:142,232,393...142,297,118 		JBrowse link
G Insr insulin receptor involved_in ISO
IEA 		GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr 8:3,200,922...3,329,649
Ensembl chr 8:3,172,061...3,329,617 		JBrowse link
G Kat2b K(lysine) acetyltransferase 2B involved_in IDA (PMID:21084751) MGI PMID:21084751 NCBI chr17:53,873,802...53,979,749
Ensembl chr17:53,873,889...53,979,748 		JBrowse link
G Mif macrophage migration inhibitory factor (glycosylation-inhibiting factor) ISO RGD PMID:11086030 RGD:1642010 NCBI chr10:75,695,187...75,696,111
Ensembl chr10:75,695,187...75,696,074 		JBrowse link
G Mlst8 MTOR associated protein, LST8 homolog (S. cerevisiae) involved_in NAS (PMID:20670887) ComplexPortal PMID:20670887 NCBI chr17:24,692,524...24,698,722
Ensembl chr17:24,692,525...24,698,052 		JBrowse link
G Mlx MAX-like protein X involved_in IDA (PMID:14742444) MGI PMID:14742444 NCBI chr11:100,978,116...100,983,033
Ensembl chr11:100,978,103...100,983,033 		JBrowse link
G Mlxipl MLX interacting protein-like involved_in IDA
IEA
IMP
ISO 		(PMID:14742444)
(PMID:15118080) 		MGI
Ensembl
BHF-UCL
GO_Central		 PMID:14742444 PMID:15118080 GO_REF:0000107 GO_REF:0000119 NCBI chr 5:135,118,744...135,168,622
Ensembl chr 5:135,118,744...135,167,236 		JBrowse link
G Mtor mechanistic target of rapamycin kinase involved_in NAS (PMID:20670887) ComplexPortal PMID:20670887 NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140 		JBrowse link
G Myc myelocytomatosis oncogene involved_in ISO RGD
GO_Central		 PMID:22842522 GO_REF:0000096 RGD:7207891 NCBI chr15:61,857,190...61,862,210
Ensembl chr15:61,857,240...61,862,223 		JBrowse link
G P2rx7 purinergic receptor P2X, ligand-gated ion channel, 7 involved_in ISO
IEA 		GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr 5:122,781,990...122,830,399
Ensembl chr 5:122,781,974...122,829,495 		JBrowse link
G Prkaa1 protein kinase, AMP-activated, alpha 1 catalytic subunit involved_in ISO
IEA
ISS 		GO_Central
Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000096 GO_REF:0000107 NCBI chr15:5,172,641...5,211,380
Ensembl chr15:5,173,343...5,211,380 		JBrowse link
G Prkaa2 protein kinase, AMP-activated, alpha 2 catalytic subunit involved_in ISS
ISO 		UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000096 NCBI chr 4:104,886,846...104,967,095
Ensembl chr 4:104,887,071...104,967,087 		JBrowse link
G Prxl2c peroxiredoxin like 2C involved_in ISO
IEA
ISS 		GO_Central
Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 GO_REF:0000119 NCBI chr13:64,437,612...64,460,524
Ensembl chr13:64,423,094...64,460,524 		JBrowse link
G Psen1 presenilin 1 involved_in ISO
IEA 		GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr12:83,734,926...83,781,869
Ensembl chr12:83,734,926...83,781,973 		JBrowse link
G Rptor regulatory associated protein of MTOR, complex 1 involved_in NAS (PMID:20670887) ComplexPortal PMID:20670887 NCBI chr11:119,493,731...119,790,417
Ensembl chr11:119,493,731...119,790,402 		JBrowse link
G Sik2 salt inducible kinase 2 acts_upstream_of_or_within IDA (PMID:21084751) MGI PMID:21084751 NCBI chr 9:50,800,944...50,920,432
Ensembl chr 9:50,804,101...50,920,373 		JBrowse link
G Slc4a4 solute carrier family 4 (anion exchanger), member 4 acts_upstream_of ISO
IMP 		(PMID:21976511) GO_Central
ARUK-UCL		 PMID:21976511 GO_REF:0000119 NCBI chr 5:88,941,717...89,387,515
Ensembl chr 5:89,034,345...89,387,512 		JBrowse link
G Src Rous sarcoma oncogene involved_in IDA (PMID:35263589) UniProt PMID:35263589 NCBI chr 2:157,265,828...157,313,758
Ensembl chr 2:157,260,364...157,313,782 		JBrowse link
G Uchl1 ubiquitin carboxy-terminal hydrolase L1 involved_in ISO
IEA 		GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr 5:66,833,464...66,844,577
Ensembl chr 5:66,833,434...66,844,577 		JBrowse link
G Zbtb20 zinc finger and BTB domain containing 20 involved_in IMP (PMID:28327662) UniProt PMID:28327662 NCBI chr16:42,728,008...43,462,981
Ensembl chr16:42,696,244...43,462,965 		JBrowse link
positive regulation of glycolytic process through fructose-6-phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpi1 glucose-6-phosphate isomerase 1 acts_upstream_of_or_within ISO (PMID:12230553) MGI PMID:12230553 NCBI chr 7:33,900,752...33,929,761
Ensembl chr 7:33,900,755...33,929,761 		JBrowse link
G Pfkfb1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 involved_in ISO (PMID:12230553) GO_Central PMID:12230553 GO_REF:0000096 NCBI chr  X:149,370,441...149,426,874
Ensembl chr  X:149,371,225...149,426,874 		JBrowse link
G Ppp2ca protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform involved_in ISO (PMID:7592845) MGI PMID:7592845 NCBI chr11:51,989,651...52,013,576
Ensembl chr11:51,989,508...52,018,605 		JBrowse link
positive regulation of guanylate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2b adenosine A2b receptor acts_upstream_of_or_within IMP (PMID:18340377) MGI PMID:18340377 NCBI chr11:62,139,810...62,157,278
Ensembl chr11:62,139,810...62,157,279 		JBrowse link
G Guca1a guanylate cyclase activator 1a (retina) involved_in ISO RGD
GO_Central		 PMID:12545196 GO_REF:0000096 RGD:1599357 NCBI chr17:47,705,482...47,724,439
Ensembl chr17:47,705,483...47,711,509 		JBrowse link
positive regulation of NAD metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nqo1 NAD(P)H dehydrogenase, quinone 1 involved_in ISO RGD
GO_Central		 PMID:29389585 GO_REF:0000096 RGD:25823193 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838 		JBrowse link
positive regulation of pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mlst8 MTOR associated protein, LST8 homolog (S. cerevisiae) involved_in NAS (PMID:20670887) ComplexPortal PMID:20670887 NCBI chr17:24,692,524...24,698,722
Ensembl chr17:24,692,525...24,698,052 		JBrowse link
G Mtor mechanistic target of rapamycin kinase involved_in NAS (PMID:20670887) ComplexPortal PMID:20670887 NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140 		JBrowse link
G Rptor regulatory associated protein of MTOR, complex 1 involved_in NAS (PMID:20670887) ComplexPortal PMID:20670887 NCBI chr11:119,493,731...119,790,417
Ensembl chr11:119,493,731...119,790,402 		JBrowse link
G Tigar Trp53 induced glycolysis regulatory phosphatase involved_in IDA (PMID:24872551) UniProt PMID:24872551 NCBI chr 6:127,062,079...127,086,564
Ensembl chr 6:127,062,079...127,086,520 		JBrowse link
regulation of ATP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pid1 phosphotyrosine interaction domain containing 1 involved_in IEA UniProt GO_REF:0000117 NCBI chr 1:84,014,014...84,317,550
Ensembl chr 1:84,014,017...84,341,901 		JBrowse link
G Sphk2 sphingosine kinase 2 involved_in IMP (PMID:25637806) UniProt PMID:25637806 NCBI chr 7:45,358,887...45,367,426
Ensembl chr 7:45,358,891...45,367,426 		JBrowse link
regulation of ATP metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp5if1 ATP synthase inhibitory factor subunit 1 involved_in ISO
IEA 		GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr 4:132,257,870...132,262,746
Ensembl chr 4:132,257,866...132,260,970 		JBrowse link
G Dnm1l dynamin 1-like involved_in IMP (PMID:20585624) ParkinsonsUK-UCL PMID:20585624 NCBI chr16:16,130,092...16,176,863
Ensembl chr16:16,130,094...16,176,823 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 involved_in IEA UniProt GO_REF:0000117 NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366 		JBrowse link
regulation of glycolytic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arl2 ADP-ribosylation factor-like 2 involved_in ISO
IEA
ISS 		GO_Central
Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 GO_REF:0000119 NCBI chr19:6,184,419...6,191,167
Ensembl chr19:6,184,404...6,191,578 		JBrowse link
G Eif6 eukaryotic translation initiation factor 6 involved_in IMP (PMID:26383020) UniProt PMID:26383020 NCBI chr 2:155,661,757...155,668,845
Ensembl chr 2:155,661,752...155,668,845 		JBrowse link
G Ep300 E1A binding protein p300 involved_in ISO
IEA
ISS 		GO_Central
Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 GO_REF:0000119 NCBI chr15:81,470,329...81,536,273
Ensembl chr15:81,469,552...81,536,278 		JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit acts_upstream_of_or_within
involved_in 		IGI
IEA
ISS
ISO 		(PMID:17437992) MGI
Ensembl
UniProt
GO_Central		 PMID:17437992 GO_REF:0000024 GO_REF:0000107 GO_REF:0000119 NCBI chr12:73,948,186...73,994,304
Ensembl chr12:73,948,149...73,994,304 		JBrowse link
G Il3 interleukin 3 acts_upstream_of_or_within IGI (PMID:17437992) MGI PMID:17437992 NCBI chr11:54,155,911...54,158,105
Ensembl chr11:54,156,129...54,158,103 		JBrowse link
G Jmjd8 jumonji domain containing 8 involved_in ISO
ISS 		GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 NCBI chr17:26,048,017...26,050,817
Ensembl chr17:26,047,841...26,050,817 		JBrowse link
G Mlxipl MLX interacting protein-like involved_in ISO RGD
GO_Central		 PMID:11724780 GO_REF:0000096 RGD:634534 NCBI chr 5:135,118,744...135,168,622
Ensembl chr 5:135,118,744...135,167,236 		JBrowse link
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) involved_in ISO
IEA
ISS 		GO_Central
Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 GO_REF:0000119 NCBI chr  X:100,683,617...100,727,957
Ensembl chr  X:100,683,666...100,727,957 		JBrowse link
G Prkag1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit involved_in IBA GO_Central GO_REF:0000033 NCBI chr15:98,710,678...98,729,354
Ensembl chr15:98,710,678...98,729,402 		JBrowse link
G Prkag2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit involved_in IEA
IBA
ISO 		Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000119 NCBI chr 5:25,067,733...25,311,576
Ensembl chr 5:25,067,742...25,305,640 		JBrowse link
G Prkag3 protein kinase, AMP-activated, gamma 3 non-catalytic subunit acts_upstream_of_or_within
involved_in 		IMP
IBA 		(PMID:15857891) MGI
GO_Central		 PMID:15857891 GO_REF:0000033 NCBI chr 1:74,778,062...74,788,623
Ensembl chr 1:74,778,081...74,788,380 		JBrowse link
G Slc2a6 solute carrier family 2 (facilitated glucose transporter), member 6 involved_in IMP
IEA
ISO 		(PMID:30431159) UniProt
Ensembl
GO_Central		 PMID:30431159 GO_REF:0000107 GO_REF:0000117 GO_REF:0000119 NCBI chr 2:26,911,375...26,918,011
Ensembl chr 2:26,911,375...26,918,010 		JBrowse link
G Trex1 three prime repair exonuclease 1 acts_upstream_of_or_within IMP (PMID:28069950) MGI PMID:28069950 NCBI chr 9:108,887,000...108,888,791
Ensembl chr 9:108,887,001...108,888,802 		JBrowse link
G Zbtb7a zinc finger and BTB domain containing 7a involved_in ISS
IEA
ISO 		UniProt
Ensembl
GO_Central		 GO_REF:0000024 GO_REF:0000107 GO_REF:0000119 NCBI chr10:80,971,113...80,988,056
Ensembl chr10:80,971,054...80,988,829 		JBrowse link
regulation of guanylate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Guca1a guanylate cyclase activator 1a (retina) acts_upstream_of_or_within IGI (PMID:15336959) MGI PMID:15336959 NCBI chr17:47,705,482...47,724,439
Ensembl chr17:47,705,483...47,711,509 		JBrowse link
G Guca1b guanylate cyclase activator 1B acts_upstream_of_or_within IGI (PMID:15336959) MGI PMID:15336959 NCBI chr17:47,692,526...47,703,892
Ensembl chr17:47,696,318...47,703,892 		JBrowse link
regulation of mitochondrial ATP synthesis coupled proton transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Antkmt adenine nucleotide translocase lysine methyltransferase involved_in IBA GO_Central GO_REF:0000033 NCBI chr17:26,009,474...26,011,761
Ensembl chr17:26,009,054...26,011,875 		JBrowse link
G Atpsckmt ATP synthase C subunit lysine N-methyltransferase involved_in ISO
IBA
IEA
IMP 		(PMID:30530489) GO_Central
Ensembl
UniProt		 PMID:30530489 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117 GO_REF:0000119 NCBI chr15:31,602,262...31,624,652
Ensembl chr15:31,601,998...31,621,373 		JBrowse link
G Dnajc30 DnaJ heat shock protein family (Hsp40) member C30 involved_in IMP (PMID:30318146) UniProt PMID:30318146 NCBI chr 5:135,093,060...135,094,219
Ensembl chr 5:135,093,056...135,094,716 		JBrowse link
regulation of NAD metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Macroh2a1 macroH2A.1 histone involved_in IDA (PMID:28991266) UniProt PMID:28991266 NCBI chr13:56,221,435...56,283,439
Ensembl chr13:56,221,432...56,284,174 		JBrowse link
regulation of NADP metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fdx1 ferredoxin 1 involved_in ISO RGD
GO_Central		 PMID:10525147 GO_REF:0000096 RGD:727285 NCBI chr 9:51,854,323...51,874,902
Ensembl chr 9:51,854,606...51,874,856 		JBrowse link
G Hnf1a HNF1 homeobox A involved_in ISO
IEA 		RGD
Ensembl
GO_Central		 PMID:20841353 GO_REF:0000096 GO_REF:0000107 RGD:150540305 NCBI chr 5:115,087,039...115,109,121
Ensembl chr 5:115,087,039...115,109,153 		JBrowse link
G Me1 malic enzyme 1, NADP(+)-dependent, cytosolic involved_in ISO
IEA 		GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr 9:86,463,416...86,577,967
Ensembl chr 9:86,463,424...86,578,006 		JBrowse link
G Me2 malic enzyme 2, NAD(+)-dependent, mitochondrial involved_in IEA
ISO 		Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr18:73,898,025...73,949,326
Ensembl chr18:73,902,974...73,948,520 		JBrowse link
regulation of pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 involved_in ISO RGD
GO_Central		 PMID:16234247 GO_REF:0000096 RGD:1625062 NCBI chr 1:192,903,917...192,946,345
Ensembl chr 1:192,903,942...192,946,383 		JBrowse link
G Tigar Trp53 induced glycolysis regulatory phosphatase involved_in ISO
IBA
IEA
ISS 		GO_Central
Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117 GO_REF:0000119 NCBI chr 6:127,062,079...127,086,564
Ensembl chr 6:127,062,079...127,086,520 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28656
    cellular process 18377
      metabolic process 11621
        purine-containing compound metabolic process 638
          purine nucleotide metabolic process 485
            regulation of purine nucleotide metabolic process 108
              negative regulation of purine nucleotide metabolic process + 35
              positive regulation of purine nucleotide metabolic process + 57
              regulation of ATP metabolic process + 94
              regulation of NAD metabolic process + 2
              regulation of NADP metabolic process + 11
              regulation of purine nucleotide biosynthetic process + 32
              regulation of purine nucleotide catabolic process + 66
Path 2
Term Annotations click to browse term
  biological_process 28656
    cellular process 18377
      metabolic process 11621
        primary metabolic process 10168
          nucleobase-containing compound metabolic process 5703
            nucleobase-containing small molecule metabolic process 736
              nucleoside phosphate metabolic process 706
                nucleotide metabolic process 541
                  purine nucleotide metabolic process 485
                    regulation of purine nucleotide metabolic process 108
                      negative regulation of purine nucleotide metabolic process + 35
                      positive regulation of purine nucleotide metabolic process + 57
                      regulation of ATP metabolic process + 94
                      regulation of NAD metabolic process + 2
                      regulation of NADP metabolic process + 11
                      regulation of purine nucleotide biosynthetic process + 32
                      regulation of purine nucleotide catabolic process + 66
paths to the root