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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of purine nucleotide metabolic process
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Accession:GO:1900542 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of purine nucleotide metabolic process.
Synonyms:exact_synonym: regulation of purine nucleotide metabolism
 narrow_synonym: regulation of purine metabolic process;   regulation of purine metabolism


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regulation of purine nucleotide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LACC1 laccase domain containing 1 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr13:43,879,178...43,893,932
Ensembl chr13:43,879,284...43,893,932 		JBrowse link
negative regulation of ATP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 ISO RGD PMID:21325440 RGD:9685453 NCBI chr10:95,694,186...95,877,266
Ensembl chr10:95,711,779...95,877,266 		JBrowse link
G MIR675 microRNA 675 acts_upstream_of IMP (PMID:31574452) ARUK-UCL PMID:31574452 NCBI chr11:1,996,759...1,996,831
Ensembl chr11:1,996,759...1,996,831 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 involved_in IMP (PMID:24289924) ParkinsonsUK-UCL PMID:24289924 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154 		JBrowse link
G PID1 phosphotyrosine interaction domain containing 1 involved_in IMP (PMID:20165904) BHF-UCL PMID:20165904 NCBI chr 2:229,023,973...229,271,287
Ensembl chr 2:228,850,526...229,271,287 		JBrowse link
negative regulation of ATP metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FIS1 fission, mitochondrial 1 involved_in IMP (PMID:32521232) ARUK-UCL PMID:32521232 NCBI chr 7:101,239,472...101,245,081
Ensembl chr 7:101,239,458...101,252,316 		JBrowse link
G TSPO translocator protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:43,151,559...43,163,242
Ensembl chr22:43,151,547...43,163,242 		JBrowse link
negative regulation of glycolytic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTN3 actinin alpha 3 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr11:66,546,395...66,563,334
Ensembl chr11:66,546,395...66,563,334 		JBrowse link
G CBFA2T3 CBFA2/RUNX1 partner transcriptional co-repressor 3 involved_in IDA (PMID:23840896) UniProt PMID:23840896 NCBI chr16:88,874,858...88,977,207
Ensembl chr16:88,874,858...88,977,207 		JBrowse link
G DDIT4 DNA damage inducible transcript 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20176937) Ensembl
MGI		 PMID:20176937 GO_REF:0000107 NCBI chr10:72,273,924...72,276,036
Ensembl chr10:72,273,919...72,276,036 		JBrowse link
G FBP1 fructose-bisphosphatase 1 involved_in IMP
IDA		 (PMID:25043030)
(PMID:19881551)		 CAFA
UniProt		 PMID:19881551 PMID:25043030 NCBI chr 9:94,603,133...94,640,263
Ensembl chr 9:94,603,133...94,640,249 		JBrowse link
G FLCN folliculin involved_in IDA (PMID:34381247) UniProt PMID:34381247 NCBI chr17:17,212,212...17,237,330
Ensembl chr17:17,212,212...17,237,188 		JBrowse link
G GIT1 GIT ArfGAP 1 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:29,573,475...29,589,648
Ensembl chr17:29,573,475...29,594,054 		JBrowse link
G HDAC4 histone deacetylase 4 involved_in IEA
ISS		 Ensembl
BHF-UCL		 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:239,048,168...239,401,649
Ensembl chr 2:239,048,168...239,401,654 		JBrowse link
G IER3 immediate early response 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19096392) Ensembl
MGI		 PMID:19096392 GO_REF:0000107 NCBI chr 6:30,743,199...30,744,547
Ensembl chr 6:30,743,199...30,744,548 		JBrowse link
G MTCH2 mitochondrial carrier 2 acts_upstream_of_or_within ISO (PMID:26219591) MGI PMID:26219591 NCBI chr11:47,604,317...47,642,559
Ensembl chr11:47,617,315...47,642,607 		JBrowse link
G MYOG myogenin ISO RGD PMID:10225962 RGD:9686132 NCBI chr 1:203,083,129...203,086,012
Ensembl chr 1:203,083,129...203,086,012 		JBrowse link
G NCOR1 nuclear receptor corepressor 1 involved_in IMP (PMID:19955185) BHF-UCL PMID:19955185 NCBI chr17:16,029,157...16,215,534
Ensembl chr17:16,029,065...16,218,185 		JBrowse link
G NUPR1 nuclear protein 1, transcriptional regulator involved_in IMP (PMID:30451898) UniProt PMID:30451898 NCBI chr16:28,532,708...28,538,974
Ensembl chr16:28,532,708...28,539,008 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha involved_in IDA (PMID:19955185) BHF-UCL PMID:19955185 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755 		JBrowse link
G PPARGC1A PPARG coactivator 1 alpha ISO RGD PMID:22343369 RGD:7242186 NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089 		JBrowse link
G SIK2 salt inducible kinase 2 involved_in ISO (PMID:21084751) MGI PMID:21084751 NCBI chr11:111,602,449...111,730,855
Ensembl chr11:111,602,449...111,730,855 		JBrowse link
G SIRT6 sirtuin 6 involved_in IEA
IDA		 (PMID:26456828) Ensembl
UniProt		 PMID:26456828 GO_REF:0000107 NCBI chr19:4,174,109...4,182,563
Ensembl chr19:4,174,109...4,182,566 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22891351) Ensembl
MGI		 PMID:22891351 GO_REF:0000107 NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568 		JBrowse link
G TIGAR TP53 induced glycolysis regulatory phosphatase involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:20935145) Ensembl
MGI
GO_Central		 PMID:20935145 GO_REF:0000033 GO_REF:0000107 NCBI chr12:4,321,213...4,360,028
Ensembl chr12:4,307,763...4,360,028 		JBrowse link
G TRIM63 tripartite motif containing 63 involved_in IMP (PMID:34244144) FlyBase PMID:34244144 NCBI chr 1:26,051,301...26,067,630
Ensembl chr 1:26,051,301...26,068,436 		JBrowse link
negative regulation of glycolytic process through fructose-6-phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:54,932,961...54,998,789
Ensembl chr  X:54,932,961...54,998,534 		JBrowse link
G PPP2CA protein phosphatase 2 catalytic subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:134,194,332...134,226,073
Ensembl chr 5:134,194,035...134,226,073 		JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:14,091,688...14,117,762
Ensembl chr19:14,091,688...14,118,084 		JBrowse link
G SLC4A1 solute carrier family 4 member 1 (Diego blood group) involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18698006) Ensembl
MGI		 PMID:18698006 GO_REF:0000107 NCBI chr17:44,248,390...44,268,135
Ensembl chr17:44,248,390...44,268,141 		JBrowse link
negative regulation of guanylate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HPCA hippocalcin ISO RGD PMID:15336960 RGD:9686438 NCBI chr 1:32,885,996...32,894,646
Ensembl chr 1:32,885,994...32,898,441 		JBrowse link
G RD3 RD3 regulator of GUCY2D involved_in IEA
IMP		 (PMID:21928830), (PMID:30559291) Ensembl
UniProt		 PMID:21928830 PMID:30559291 GO_REF:0000107 NCBI chr 1:211,476,522...211,492,162
Ensembl chr 1:211,476,522...211,492,162 		JBrowse link
negative regulation of mitochondrial ATP synthesis coupled proton transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP5IF1 ATP synthase inhibitory factor subunit 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr 1:28,236,124...28,238,100
Ensembl chr 1:28,236,109...28,246,906 		JBrowse link
negative regulation of pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALDOB aldolase, fructose-bisphosphate B involved_in IMP (PMID:35122041) UniProt PMID:35122041 NCBI chr 9:101,420,560...101,435,774
Ensembl chr 9:101,420,560...101,449,664 		JBrowse link
G TP53 tumor protein p53 involved_in IMP (PMID:21336310) CACAO PMID:21336310 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
positive regulation of ATP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCY10 adenylate cyclase 10 involved_in ISO
IEA		 RGD
Ensembl		 PMID:31172217 GO_REF:0000107 RGD:329403053 NCBI chr 1:167,809,386...167,914,134
Ensembl chr 1:167,809,386...167,914,215 		JBrowse link
G BCL2L1 BCL2 like 1 involved_in ISO PMID:23792689 CAFA PMID:23792689 RGD:12793033 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989 		JBrowse link
G ENO1 enolase 1 involved_in IDA
IGI		 (PMID:15459207) CAFA PMID:15459207 NCBI chr 1:8,861,000...8,878,686
Ensembl chr 1:8,861,000...8,879,190 		JBrowse link
G HNF1A HNF1 homeobox A ISO RGD PMID:20841353 RGD:150540305 NCBI chr12:120,978,543...121,002,512
Ensembl chr12:120,978,543...121,002,512 		JBrowse link
G IL4 interleukin 4 involved_in ISS ARUK-UCL GO_REF:0000024 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 involved_in ISO PMID:15459207 CAFA PMID:15459207 RGD:12793039 NCBI chr15:66,386,912...66,491,544
Ensembl chr15:66,386,837...66,491,656 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor ISO RGD PMID:22629444 RGD:7240532 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951 		JBrowse link
G NDUFC2 NADH:ubiquinone oxidoreductase subunit C2 ISO RGD PMID:26888427 RGD:11040458 NCBI chr11:78,068,297...78,079,862
Ensembl chr11:78,068,297...78,079,862 		JBrowse link
G PID1 phosphotyrosine interaction domain containing 1 involved_in ISS
IEA		 BHF-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:229,023,973...229,271,287
Ensembl chr 2:228,850,526...229,271,287 		JBrowse link
G PINK1 PTEN induced kinase 1 involved_in TAS (PMID:20871098) ParkinsonsUK-UCL PMID:20871098 NCBI chr 1:20,633,458...20,651,511
Ensembl chr 1:20,633,458...20,651,511 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha acts_upstream_of IMP (PMID:31574452) ARUK-UCL PMID:31574452 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase ISO RGD PMID:24096089 RGD:10413842 NCBI chr 6:161,347,417...162,727,766
Ensembl chr 6:161,347,417...162,727,775 		JBrowse link
G SIRT1 sirtuin 1 involved_in ISO (PMID:24747689) AgBase PMID:24747689 NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390 		JBrowse link
G SLC25A12 solute carrier family 25 member 12 ISO RGD PMID:19764902 RGD:13628741 NCBI chr 2:171,783,405...171,894,244
Ensembl chr 2:171,783,405...171,999,859 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 ISO RGD PMID:23590160 RGD:8694322 NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568 		JBrowse link
G TAFAZZIN tafazzin, phospholipid-lysophospholipid transacylase involved_in ISO
IEA		 RGD
Ensembl		 PMID:20348225 GO_REF:0000107 RGD:13432160 NCBI chr  X:154,411,539...154,421,726
Ensembl chr  X:154,411,524...154,421,726 		JBrowse link
G TMSB4X thymosin beta 4 X-linked involved_in IDA (PMID:21106936) CAFA PMID:21106936 NCBI chr  X:12,975,110...12,977,223
Ensembl chr  X:12,975,110...12,977,227 		JBrowse link
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in ISS
IEA		 ARUK-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:41,158,508...41,163,116
Ensembl chr 6:41,158,506...41,163,186 		JBrowse link
G VCP valosin containing protein involved_in IMP (PMID:23498975) ParkinsonsUK-UCL PMID:23498975 NCBI chr 9:35,056,064...35,072,625
Ensembl chr 9:35,053,928...35,072,668 		JBrowse link
positive regulation of ATP metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BEND3 BEN domain containing 3 involved_in IDA (PMID:28977671) UniProt PMID:28977671 NCBI chr 6:107,065,182...107,115,515
Ensembl chr 6:107,065,182...107,115,515 		JBrowse link
positive regulation of glycolytic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APP amyloid beta precursor protein involved_in IGI (PMID:29061364) ARUK-UCL PMID:29061364 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,535...26,171,128 		JBrowse link
G ARNT aryl hydrocarbon receptor nuclear translocator acts_upstream_of IDA (PMID:8089148) BHF-UCL PMID:8089148 NCBI chr 1:150,809,713...150,876,599
Ensembl chr 1:150,809,713...150,876,708 		JBrowse link
G ESRRB estrogen related receptor beta involved_in ISO PMID:24481529 BHF-UCL PMID:24481529 RGD:12910990 NCBI chr14:76,310,777...76,501,837
Ensembl chr14:76,310,712...76,501,837 		JBrowse link
G GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic involved_in TAS (PMID:10714828) UniProt PMID:10714828 NCBI chr19:35,533,456...35,545,319
Ensembl chr19:35,533,455...35,545,319 		JBrowse link
G GCK glucokinase ISO RGD PMID:17553851 RGD:2301905 NCBI chr 7:44,143,213...44,189,439
Ensembl chr 7:44,143,213...44,198,170 		JBrowse link
G GPD1 glycerol-3-phosphate dehydrogenase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11147825) Ensembl
MGI		 PMID:11147825 GO_REF:0000107 NCBI chr12:50,104,008...50,111,313
Ensembl chr12:50,103,982...50,111,313 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha acts_upstream_of IDA (PMID:8089148) BHF-UCL PMID:8089148 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259 		JBrowse link
G HTR2A 5-hydroxytryptamine receptor 2A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17408640) Ensembl
MGI		 PMID:17408640 GO_REF:0000107 NCBI chr13:46,831,546...46,898,082
Ensembl chr13:46,831,546...46,897,076 		JBrowse link
G IFNG interferon gamma involved_in ISS ARUK-UCL GO_REF:0000024 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IGF1 insulin like growth factor 1 involved_in IDA (PMID:7688386) BHF-UCL PMID:7688386 NCBI chr12:102,395,874...102,481,839
Ensembl chr12:102,395,874...102,481,744 		JBrowse link
G INS insulin involved_in IMP
IDA		 (PMID:381941)
(PMID:7688386)		 BHF-UCL PMID:381941 PMID:7688386 NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,221 		JBrowse link
G INSR insulin receptor involved_in IMP (PMID:7693131) BHF-UCL PMID:7693131 NCBI chr19:7,112,265...7,294,414
Ensembl chr19:7,112,255...7,294,414 		JBrowse link
G KAT2B lysine acetyltransferase 2B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:20,040,446...20,154,404
Ensembl chr 3:20,040,446...20,154,404 		JBrowse link
G MIF macrophage migration inhibitory factor ISO RGD PMID:11086030 RGD:1642010 NCBI chr22:23,894,383...23,895,223
Ensembl chr22:23,894,383...23,895,227 		JBrowse link
G MLST8 MTOR associated protein, LST8 homolog involved_in NAS (PMID:20670887) ComplexPortal PMID:20670887 NCBI chr16:2,205,454...2,209,453
Ensembl chr16:2,204,248...2,209,453 		JBrowse link
G MLX MAX dimerization protein MLX involved_in ISO (PMID:14742444) MGI PMID:14742444 NCBI chr17:42,567,100...42,573,203
Ensembl chr17:42,567,072...42,573,239 		JBrowse link
G MLXIPL MLX interacting protein like involved_in IEA
IMP		 (PMID:19995986) Ensembl
BHF-UCL		 PMID:19995986 GO_REF:0000107 NCBI chr 7:73,593,202...73,647,907
Ensembl chr 7:73,593,194...73,624,543 		JBrowse link
G MTOR mechanistic target of rapamycin kinase involved_in NAS (PMID:20670887) ComplexPortal PMID:20670887 NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor ISO RGD PMID:22842522 RGD:7207891 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951 		JBrowse link
G P2RX7 purinergic receptor P2X 7 involved_in IMP (PMID:22898868) CACAO PMID:22898868 NCBI chr12:121,132,876...121,188,032
Ensembl chr12:121,132,819...121,188,032 		JBrowse link
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:40,759,389...40,798,374
Ensembl chr 5:40,759,389...40,798,374 		JBrowse link
G PRKAA2 protein kinase AMP-activated catalytic subunit alpha 2 involved_in ISS UniProt GO_REF:0000024 NCBI chr 1:56,645,314...56,715,335
Ensembl chr 1:56,645,314...56,715,335 		JBrowse link
G PRXL2C peroxiredoxin like 2C involved_in IMP (PMID:29901208) UniProt PMID:29901208 NCBI chr 9:96,639,577...96,655,317
Ensembl chr 9:96,639,577...96,655,317 		JBrowse link
G PSEN1 presenilin 1 involved_in IGI (PMID:29061364) ARUK-UCL PMID:29061364 NCBI chr14:73,136,417...73,223,691
Ensembl chr14:73,136,418...73,223,691 		JBrowse link
G RPTOR regulatory associated protein of MTOR complex 1 involved_in NAS (PMID:20670887) ComplexPortal PMID:20670887 NCBI chr17:80,544,838...80,966,368
Ensembl chr17:80,544,819...80,966,371 		JBrowse link
G SLC4A4 solute carrier family 4 member 4 acts_upstream_of IGI
ISS		 (PMID:21976511) ARUK-UCL PMID:21976511 NCBI chr 4:71,062,660...71,572,083
Ensembl chr 4:71,062,667...71,572,087 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:37,344,699...37,406,050
Ensembl chr20:37,344,685...37,406,050 		JBrowse link
G UCHL1 ubiquitin C-terminal hydrolase L1 involved_in IMP (PMID:34244144) FlyBase PMID:34244144 NCBI chr 4:41,256,928...41,268,455
Ensembl chr 4:41,256,413...41,268,455 		JBrowse link
G ZBTB20 zinc finger and BTB domain containing 20 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:114,314,500...115,147,288
Ensembl chr 3:114,314,500...115,147,292 		JBrowse link
positive regulation of glycolytic process through fructose-6-phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:54,932,961...54,998,789
Ensembl chr  X:54,932,961...54,998,534 		JBrowse link
positive regulation of guanylate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA2B adenosine A2b receptor acts_upstream_of_or_within ISO (PMID:18340377) MGI PMID:18340377 NCBI chr17:15,850,362...15,975,746
Ensembl chr17:15,945,130...15,975,746 		JBrowse link
G GUCA1A guanylate cyclase activator 1A involved_in ISO
ISS		 RGD
UniProt		 PMID:12545196 GO_REF:0000024 RGD:1599357 NCBI chr 6:42,173,364...42,180,056
Ensembl chr 6:42,173,364...42,181,338 		JBrowse link
G GUCA1ANB-GUCA1A GUCA1ANB-GUCA1A readthrough involved_in ISS UniProt GO_REF:0000024 NCBI chr 6:42,155,406...42,180,056
Ensembl chr 6:42,155,406...42,180,056 		JBrowse link
G NOS3 nitric oxide synthase 3 involved_in IMP
ISS		 (PMID:17502619) BHF-UCL PMID:17502619 GO_REF:0000024 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588 		JBrowse link
positive regulation of pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MLST8 MTOR associated protein, LST8 homolog involved_in NAS (PMID:20670887) ComplexPortal PMID:20670887 NCBI chr16:2,205,454...2,209,453
Ensembl chr16:2,204,248...2,209,453 		JBrowse link
G MTOR mechanistic target of rapamycin kinase involved_in NAS (PMID:20670887) ComplexPortal PMID:20670887 NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556 		JBrowse link
G RPTOR regulatory associated protein of MTOR complex 1 involved_in NAS (PMID:20670887) ComplexPortal PMID:20670887 NCBI chr17:80,544,838...80,966,368
Ensembl chr17:80,544,819...80,966,371 		JBrowse link
G TIGAR TP53 induced glycolysis regulatory phosphatase involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:4,321,213...4,360,028
Ensembl chr12:4,307,763...4,360,028 		JBrowse link
regulation of 'de novo' NAD biosynthetic process from tryptophan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACMSD aminocarboxymuconate semialdehyde decarboxylase involved_in TAS (PMID:12140278), (PMID:19843166) ParkinsonsUK-UCL PMID:12140278 PMID:19843166 NCBI chr 2:134,838,616...134,902,034
Ensembl chr 2:134,838,616...134,902,034 		JBrowse link
regulation of acetyl-CoA biosynthetic process from pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDK1 pyruvate dehydrogenase kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:172,555,373...172,724,312
Ensembl chr 2:172,555,373...172,608,669 		JBrowse link
G PDK2 pyruvate dehydrogenase kinase 2 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:50,094,737...50,112,152
Ensembl chr17:50,094,737...50,112,152 		JBrowse link
G PDK3 pyruvate dehydrogenase kinase 3 involved_in IMP (PMID:22865452) UniProt PMID:22865452 NCBI chr  X:24,465,286...24,550,466
Ensembl chr  X:24,465,244...24,550,466 		JBrowse link
G PDK4 pyruvate dehydrogenase kinase 4 involved_in IEA
IMP		 (PMID:21852536) Ensembl
UniProt		 PMID:21852536 GO_REF:0000107 NCBI chr 7:95,583,499...95,596,516
Ensembl chr 7:95,583,499...95,596,516 		JBrowse link
G TPK1 thiamin pyrophosphokinase 1 involved_in IMP (PMID:38547260) UniProt PMID:38547260 NCBI chr 7:144,451,941...144,836,437
Ensembl chr 7:144,451,941...144,836,395 		JBrowse link
regulation of acyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SNCA synuclein alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16636270)
(PMID:16734431)		 Ensembl
MGI		 PMID:16636270 PMID:16734431 GO_REF:0000107 NCBI chr 4:89,724,099...89,838,304
Ensembl chr 4:89,700,345...89,838,315 		JBrowse link
regulation of ATP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SPHK2 sphingosine kinase 2 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr19:48,619,506...48,630,405
Ensembl chr19:48,619,291...48,630,717 		JBrowse link
regulation of ATP metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP5IF1 ATP synthase inhibitory factor subunit 1 involved_in IMP (PMID:24005319) ParkinsonsUK-UCL PMID:24005319 NCBI chr 1:28,236,124...28,238,100
Ensembl chr 1:28,236,109...28,246,906 		JBrowse link
G DNM1L dynamin 1 like involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:32,679,301...32,745,650
Ensembl chr12:32,679,200...32,745,650 		JBrowse link
regulation of glycolytic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARL2 ADP ribosylation factor like GTPase 2 involved_in IMP (PMID:30945270) UniProt PMID:30945270 NCBI chr11:65,014,160...65,022,184
Ensembl chr11:65,014,160...65,022,184 		JBrowse link
G EIF6 eukaryotic translation initiation factor 6 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr20:35,278,906...35,284,772
Ensembl chr20:35,278,907...35,284,985 		JBrowse link
G EP300 E1A binding protein p300 involved_in IDA (PMID:29775581) UniProt PMID:29775581 NCBI chr22:41,092,592...41,180,077
Ensembl chr22:41,092,510...41,180,077 		JBrowse link
G GCK glucokinase involved_in NAS (PMID:9570959) BHF-UCL PMID:9570959 NCBI chr 7:44,143,213...44,189,439
Ensembl chr 7:44,143,213...44,198,170 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha involved_in
acts_upstream_of_or_within		 IDA
ISO
IEA		 (PMID:32697943)
(PMID:17437992)		 UniProt
MGI
Ensembl		 PMID:17437992 PMID:32697943 GO_REF:0000107 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259 		JBrowse link
G IL3 interleukin 3 acts_upstream_of_or_within ISO (PMID:17437992) MGI PMID:17437992 NCBI chr 5:132,060,655...132,063,204
Ensembl chr 5:132,060,655...132,063,204 		JBrowse link
G JMJD8 jumonji domain containing 8 involved_in IMP (PMID:27199445) UniProt PMID:27199445 NCBI chr16:681,670...684,334
Ensembl chr16:681,670...684,528 		JBrowse link
G MLXIPL MLX interacting protein like ISO RGD PMID:11724780 RGD:634534 NCBI chr 7:73,593,202...73,647,907
Ensembl chr 7:73,593,194...73,624,543 		JBrowse link
G OGT O-linked N-acetylglucosamine (GlcNAc) transferase involved_in IDA (PMID:22923583) UniProt PMID:22923583 NCBI chr  X:71,533,104...71,575,892
Ensembl chr  X:71,533,087...71,575,892 		JBrowse link
G PRKAG1 protein kinase AMP-activated non-catalytic subunit gamma 1 involved_in TAS (PMID:8663446) BHF-UCL PMID:8663446 NCBI chr12:49,002,274...49,018,776
Ensembl chr12:49,002,274...49,018,807 		JBrowse link
G PRKAG2 protein kinase AMP-activated non-catalytic subunit gamma 2 involved_in IMP (PMID:15877279) BHF-UCL PMID:15877279 NCBI chr 7:151,556,127...151,877,115
Ensembl chr 7:151,556,124...151,877,214 		JBrowse link
G PRKAG3 protein kinase AMP-activated non-catalytic subunit gamma 3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:15857891) MGI
Ensembl		 PMID:15857891 GO_REF:0000107 NCBI chr 2:218,822,308...218,831,803
Ensembl chr 2:218,822,308...218,832,086 		JBrowse link
G SLC2A6 solute carrier family 2 member 6 involved_in IEA
IMP		 (PMID:30431159) Ensembl
UniProt		 PMID:30431159 GO_REF:0000107 NCBI chr 9:133,471,094...133,479,099
Ensembl chr 9:133,471,094...133,479,127 		JBrowse link
G TREX1 three prime repair exonuclease 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:28069950) Ensembl
MGI		 PMID:28069950 GO_REF:0000107 NCBI chr 3:48,465,830...48,467,645
Ensembl chr 3:48,465,811...48,467,645 		JBrowse link
G ZBTB7A zinc finger and BTB domain containing 7A involved_in IMP (PMID:26455326) UniProt PMID:26455326 NCBI chr19:4,043,303...4,066,899
Ensembl chr19:4,043,303...4,066,899 		JBrowse link
regulation of guanylate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GUCA1A guanylate cyclase activator 1A acts_upstream_of_or_within ISO (PMID:15336959) MGI PMID:15336959 NCBI chr 6:42,173,364...42,180,056
Ensembl chr 6:42,173,364...42,181,338 		JBrowse link
G GUCA1B guanylate cyclase activator 1B acts_upstream_of_or_within ISO (PMID:15336959) MGI PMID:15336959 NCBI chr 6:42,183,284...42,194,956
Ensembl chr 6:42,183,284...42,194,956 		JBrowse link
regulation of mitochondrial ATP synthesis coupled proton transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANTKMT adenine nucleotide translocase lysine methyltransferase involved_in IBA GO_Central GO_REF:0000033 NCBI chr16:721,146...722,590
Ensembl chr16:720,581...722,590 		JBrowse link
G ATPSCKMT ATP synthase c subunit lysine N-methyltransferase involved_in IMP
IBA
IEA		 (PMID:30530489) UniProt
GO_Central
Ensembl		 PMID:30530489 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:10,225,507...10,249,888
Ensembl chr 5:10,225,507...10,249,897 		JBrowse link
G DNAJC30 DnaJ heat shock protein family (Hsp40) member C30 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:73,680,918...73,683,453
Ensembl chr 7:73,680,918...73,683,453 		JBrowse link
regulation of NAD metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MACROH2A1 macroH2A.1 histone involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:135,334,381...135,399,887
Ensembl chr 5:135,334,381...135,399,914 		JBrowse link
regulation of NADP metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HNF1A HNF1 homeobox A ISO RGD PMID:20841353 RGD:150540305 NCBI chr12:120,978,543...121,002,512
Ensembl chr12:120,978,543...121,002,512 		JBrowse link
G ME1 malic enzyme 1 involved_in IMP (PMID:23334421) CACAO PMID:23334421 NCBI chr 6:83,210,402...83,431,051
Ensembl chr 6:83,210,402...83,431,051 		JBrowse link
G ME2 malic enzyme 2 involved_in IMP (PMID:23334421) CACAO PMID:23334421 NCBI chr18:50,879,118...50,954,257
Ensembl chr18:50,879,080...50,954,257 		JBrowse link
regulation of pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSD11B1 hydroxysteroid 11-beta dehydrogenase 1 ISO RGD PMID:16234247 RGD:1625062 NCBI chr 1:209,686,179...209,734,929
Ensembl chr 1:209,686,178...209,734,949 		JBrowse link
G TIGAR TP53 induced glycolysis regulatory phosphatase involved_in IMP
IBA		 (PMID:25928429) UniProt
GO_Central		 PMID:25928429 GO_REF:0000033 NCBI chr12:4,321,213...4,360,028
Ensembl chr12:4,307,763...4,360,028 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19777
    metabolic process 13069
      purine-containing compound metabolic process 640
        purine nucleotide metabolic process 606
          regulation of purine nucleotide metabolic process 113
            negative regulation of purine nucleotide metabolic process + 34
            positive regulation of purine nucleotide metabolic process + 54
            regulation of ATP metabolic process + 92
            regulation of NAD metabolic process + 2
            regulation of NADP metabolic process + 10
            regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway + 0
            regulation of purine nucleotide biosynthetic process + 41
            regulation of purine nucleotide catabolic process + 64
            regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA + 0
Path 2
Term Annotations click to browse term
  biological_process 19777
    biological regulation 13517
      regulation of biological process 13119
        regulation of cellular process 12478
          regulation of cellular metabolic process 6924
            regulation of phosphorus metabolic process 1252
              regulation of phosphate metabolic process 1249
                regulation of nucleotide metabolic process 114
                  regulation of purine nucleotide metabolic process 113
                    negative regulation of purine nucleotide metabolic process + 34
                    positive regulation of purine nucleotide metabolic process + 54
                    regulation of ATP metabolic process + 92
                    regulation of NAD metabolic process + 2
                    regulation of NADP metabolic process + 10
                    regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway + 0
                    regulation of purine nucleotide biosynthetic process + 41
                    regulation of purine nucleotide catabolic process + 64
                    regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA + 0
paths to the root