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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of purine nucleotide metabolic process
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Accession:GO:1900542 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of purine nucleotide metabolic process.
Synonyms:exact_synonym: regulation of purine nucleotide metabolism
 narrow_synonym: regulation of purine metabolic process;   regulation of purine metabolism


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regulation of purine nucleotide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LACC1 laccase domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:6,824,942...7,002,888 JBrowse link
negative regulation of ATP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 ISO RGD PMID:21325440 RGD:9685453 NCBI chr28:9,181,851...9,311,835
Ensembl chr28:9,211,050...9,323,939 		JBrowse link
G FLCN folliculin involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:42,176,093...42,195,718
Ensembl chr 5:42,176,291...42,195,711 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:38,503,072...38,542,556
Ensembl chr 7:38,503,067...38,542,127 		JBrowse link
G PID1 phosphotyrosine interaction domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:41,424,307...41,649,736
Ensembl chr25:41,425,811...41,652,672 		JBrowse link
negative regulation of ATP metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FIS1 fission, mitochondrial 1 involved_in ISO (PMID:32521232) ARUK-UCL PMID:32521232 NCBI chr 6:8,642,014...8,645,812
Ensembl chr 6:8,642,039...8,648,851 		JBrowse link
G TSPO translocator protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:22,388,498...22,399,329
Ensembl chr10:22,274,405...22,399,297 		JBrowse link
negative regulation of guanylate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HPCA hippocalcin ISO RGD PMID:15336960 RGD:9686438 NCBI chr 2:68,464,631...68,473,661
Ensembl chr 2:68,465,280...68,473,310 		JBrowse link
G RD3 RD3 regulator of GUCY2D involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:9,876,003...9,887,267 JBrowse link
negative regulation of pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TP53 tumor protein p53 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:32,561,406...32,565,149
Ensembl chr 5:32,560,598...32,574,109 		JBrowse link
positive regulation of ATP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCY10 adenylate cyclase 10 ISO RGD PMID:31172217 RGD:329403053 NCBI chr 7:30,576,445...30,660,926
Ensembl chr 7:30,577,591...30,660,926 		JBrowse link
G BCL2L1 BCL2 like 1 involved_in ISO PMID:23792689 CAFA PMID:23792689 RGD:12793033 NCBI chr24:21,145,214...21,209,425
Ensembl chr24:21,145,215...21,196,355 		JBrowse link
G ENO1 enolase 1 involved_in ISO (PMID:15459207) CAFA PMID:15459207 NCBI chr 5:62,300,805...62,314,508
Ensembl chr 5:62,300,808...62,304,093 		JBrowse link
G HNF1A HNF1 homeobox A ISO RGD PMID:20841353 RGD:150540305 NCBI chr26:16,805,690...16,826,065
Ensembl chr26:16,805,690...16,824,790 		JBrowse link
G IL4 interleukin 4 involved_in ISO (MGI:6304699|PMID:29061364) ARUK-UCL PMID:29061364 MGI:6304699 NCBI chr11:20,972,693...20,981,539
Ensembl chr11:20,972,690...20,981,534 		JBrowse link
G LOC100683370 thymosin beta-4 involved_in ISO (PMID:21106936) CAFA PMID:21106936 NCBI chr 1:21,127,694...21,128,346 JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 involved_in ISO PMID:15459207 CAFA PMID:15459207 RGD:12793039 NCBI chr30:30,683,192...30,760,479
Ensembl chr30:30,683,107...30,760,479 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor ISO RGD PMID:22629444 RGD:7240532 NCBI chr13:25,200,772...25,205,309
Ensembl chr13:25,200,577...25,205,309 		JBrowse link
G NDUFC2 NADH:ubiquinone oxidoreductase subunit C2 ISO RGD PMID:26888427 RGD:11040458 NCBI chr21:20,748,452...20,758,236 JBrowse link
G PID1 phosphotyrosine interaction domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:41,424,307...41,649,736
Ensembl chr25:41,425,811...41,652,672 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha acts_upstream_of ISO (PMID:31574452) ARUK-UCL PMID:31574452 NCBI chr10:19,934,020...20,006,096
Ensembl chr10:19,934,165...20,006,146 		JBrowse link
G PPARGC1A PPARG coactivator 1 alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:85,645,942...86,284,570
Ensembl chr 3:86,016,140...86,281,269 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase ISO RGD PMID:24096089 RGD:10413842 NCBI chr 1:49,886,887...51,201,930
Ensembl chr 1:49,889,005...51,201,764 		JBrowse link
G SIRT1 sirtuin 1 involved_in ISO (PMID:24747689) AgBase PMID:24747689 NCBI chr 4:19,188,616...19,220,031
Ensembl chr 4:19,188,675...19,218,279 		JBrowse link
G SLC25A12 solute carrier family 25 member 12 ISO RGD PMID:19764902 RGD:13628741 NCBI chr36:16,185,011...16,391,080
Ensembl chr36:16,185,649...16,483,016 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 ISO RGD PMID:23590160 RGD:8694322 NCBI chr 9:20,539,660...20,614,631
Ensembl chr 9:20,539,697...20,612,672 		JBrowse link
G TAFAZZIN tafazzin, phospholipid-lysophospholipid transacylase ISO RGD PMID:20348225 RGD:13432160 NCBI chr  X:122,111,608...122,125,714
Ensembl chr  X:122,111,434...122,125,506 		JBrowse link
G VCP valosin containing protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:51,636,986...51,651,749
Ensembl chr11:51,637,411...51,651,714 		JBrowse link
positive regulation of ATP metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BEND3 BEN domain containing 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:64,302,403...64,324,396
Ensembl chr12:64,306,140...64,322,725 		JBrowse link
positive regulation of guanylate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA2B adenosine A2b receptor acts_upstream_of_or_within ISO (MGI:3794903|PMID:18340377) MGI PMID:18340377 MGI:3794903 NCBI chr 5:39,884,375...39,908,214 JBrowse link
G NOS2 nitric oxide synthase 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 9:42,171,821...42,210,217
Ensembl chr 9:42,171,821...42,208,588 		JBrowse link
G NOS3 nitric oxide synthase 3 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr16:15,054,196...15,072,454
Ensembl chr16:15,011,344...15,072,277 		JBrowse link
positive regulation of pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TIGAR TP53 induced glycolysis regulatory phosphatase involved_in ISO (MGI:5574521|PMID:24872551) UniProt PMID:24872551 MGI:5574521 NCBI chr27:40,521,751...40,549,304
Ensembl chr27:40,523,314...40,549,332 		JBrowse link
regulation of acetyl-CoA biosynthetic process from pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDK1 pyruvate dehydrogenase kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr36:16,918,329...16,944,532
Ensembl chr36:16,918,058...16,944,620 		JBrowse link
G PDK2 pyruvate dehydrogenase kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:26,099,457...26,116,094
Ensembl chr 9:26,100,343...26,115,423 		JBrowse link
G PDK3 pyruvate dehydrogenase kinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:19,994,383...20,058,979
Ensembl chr  X:19,994,393...20,058,485 		JBrowse link
G PDK4 pyruvate dehydrogenase kinase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:20,825,861...20,839,290
Ensembl chr14:20,827,831...20,839,256 		JBrowse link
regulation of acyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SNCA synuclein alpha acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3628986|PMID:16636270)
(MGI:3629421|PMID:16734431)		 MGI
Ensembl		 PMID:16636270 PMID:16734431 GO_REF:0000107 MGI:3628986 MGI:3629421 NCBI chr32:12,915,871...13,079,338
Ensembl chr32:12,916,215...13,060,383 		JBrowse link
regulation of ATP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SPHK2 sphingosine kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:107,681,425...107,689,790
Ensembl chr 1:107,680,599...107,689,707 		JBrowse link
regulation of ATP metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP5IF1 ATP synthase inhibitory factor subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:72,188,562...72,191,344
Ensembl chr 2:72,188,266...72,191,326 		JBrowse link
G DNM1L dynamin 1 like involved_in ISO (MGI:4459561|PMID:20585624) ParkinsonsUK-UCL PMID:20585624 MGI:4459561 NCBI chr27:16,161,855...16,211,983
Ensembl chr27:16,163,357...16,211,957 		JBrowse link
regulation of guanylate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GUCA1A guanylate cyclase activator 1A involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:10,786,284...10,795,974
Ensembl chr12:10,788,424...10,795,442 		JBrowse link
G GUCA1B guanylate cyclase activator 1B acts_upstream_of_or_within ISO (MGI:3052899|PMID:15336959) MGI PMID:15336959 MGI:3052899 NCBI chr12:10,796,961...10,806,796
Ensembl chr12:10,797,921...10,834,237 		JBrowse link
regulation of mitochondrial ATP synthesis coupled proton transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATPSCKMT ATP synthase c subunit lysine N-methyltransferase involved_in IEA Ensembl GO_REF:0000107 NCBI chr34:4,049,015...4,242,294
Ensembl chr34:4,049,126...4,067,333 		JBrowse link
G DNAJC30 DnaJ heat shock protein family (Hsp40) member C30 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:6,595,233...6,596,440
Ensembl chr 6:6,595,294...6,595,974 		JBrowse link
regulation of NAD metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MACROH2A1 macroH2A.1 histone involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:23,369,957...23,448,235
Ensembl chr11:23,370,300...23,438,219 		JBrowse link
regulation of NADP metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HNF1A HNF1 homeobox A ISO RGD PMID:20841353 RGD:150540305 NCBI chr26:16,805,690...16,826,065
Ensembl chr26:16,805,690...16,824,790 		JBrowse link
G ME1 malic enzyme 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:43,623,413...43,793,590
Ensembl chr12:43,624,945...43,828,775 		JBrowse link
G ME2 malic enzyme 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:23,985,482...24,032,642
Ensembl chr 1:23,985,994...24,025,747 		JBrowse link
regulation of pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSD11B1 hydroxysteroid 11-beta dehydrogenase 1 ISO RGD PMID:16234247 RGD:1625062 NCBI chr 7:8,344,380...8,409,901
Ensembl chr 7:8,344,447...8,409,897 		JBrowse link
G PGAM1 phosphoglycerate mutase 1 involved_in ISO (PMID:12189148) UniProt PMID:12189148 NCBI chr28:10,720,235...10,727,709
Ensembl chr28:10,720,094...10,930,286 		JBrowse link
G TIGAR TP53 induced glycolysis regulatory phosphatase involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:40,521,751...40,549,304
Ensembl chr27:40,523,314...40,549,332 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16545
    metabolic process 10572
      small molecule metabolic process 1672
        regulation of small molecule metabolic process 374
          regulation of nucleotide metabolic process 50
            regulation of purine nucleotide metabolic process 49
              negative regulation of purine nucleotide metabolic process + 9
              positive regulation of purine nucleotide metabolic process + 23
              regulation of ATP metabolic process + 29
              regulation of NAD metabolic process + 1
              regulation of NADP metabolic process + 7
              regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway + 0
              regulation of purine nucleotide biosynthetic process + 36
              regulation of purine nucleotide catabolic process + 0
              regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA + 0
Path 2
Term Annotations click to browse term
  biological_process 16545
    cellular process 14656
      cellular metabolic process 6551
        heterocycle metabolic process 2684
          nucleobase-containing compound metabolic process 2528
            nucleobase-containing small molecule metabolic process 518
              nucleoside phosphate metabolic process 461
                nucleotide metabolic process 455
                  purine nucleotide metabolic process 398
                    regulation of purine nucleotide metabolic process 49
                      negative regulation of purine nucleotide metabolic process + 9
                      positive regulation of purine nucleotide metabolic process + 23
                      regulation of ATP metabolic process + 29
                      regulation of NAD metabolic process + 1
                      regulation of NADP metabolic process + 7
                      regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway + 0
                      regulation of purine nucleotide biosynthetic process + 36
                      regulation of purine nucleotide catabolic process + 0
                      regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA + 0
paths to the root