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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of purine nucleotide metabolic process
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Accession:GO:1900542 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of purine nucleotide metabolic process.
Synonyms:exact_synonym: regulation of purine nucleotide metabolism
 narrow_synonym: regulation of purine metabolic process;   regulation of purine metabolism

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regulation of purine nucleotide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lacc1 laccase domain containing 1 involved_in ISO (MGI:6436442|PMID:31978345) UniProt PMID:31978345 MGI:6436442 NCBI chrNW_004955518:1,794,067...1,809,150
Ensembl chrNW_004955518:1,793,352...1,805,808 		JBrowse link
negative regulation of ATP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 ISO RGD PMID:21325440 RGD:9685453 NCBI chrNW_004955507:2,035,918...2,141,327
Ensembl chrNW_004955507:2,036,050...2,137,377 		JBrowse link
G Parp1 poly(ADP-ribose) polymerase 1 involved_in ISO (PMID:24289924) ParkinsonsUK-UCL PMID:24289924 NCBI chrNW_004955489:520,875...557,609
Ensembl chrNW_004955489:520,875...557,615 		JBrowse link
G Pid1 phosphotyrosine interaction domain containing 1 involved_in ISO (PMID:20165904) BHF-UCL PMID:20165904 NCBI chrNW_004955453:5,680,418...5,913,236
Ensembl chrNW_004955453:5,680,211...5,911,589 		JBrowse link
negative regulation of ATP metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fis1 fission, mitochondrial 1 involved_in ISO (PMID:32521232) ARUK-UCL PMID:32521232 NCBI chrNW_004955456:16,057,158...16,060,623
Ensembl chrNW_004955456:16,038,221...16,060,623 		JBrowse link
G Tspo translocator protein involved_in ISO (MGI:5689082|PMID:25470454) ParkinsonsUK-UCL PMID:25470454 MGI:5689082 NCBI chrNW_004955413:28,309,105...28,315,075
Ensembl chrNW_004955413:28,308,658...28,315,075 		JBrowse link
negative regulation of glycolytic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn3 actinin alpha 3 involved_in ISO (MGI:3759354|PMID:17828264) UniProt PMID:17828264 MGI:3759354 NCBI chrNW_004955422:18,799,372...18,812,458
Ensembl chrNW_004955422:18,799,372...18,812,711 		JBrowse link
G Cbfa2t3 CBFA2/RUNX1 partner transcriptional co-repressor 3 involved_in ISO (PMID:23840896) UniProt PMID:23840896 NCBI chrNW_004955541:2,724,369...2,777,540
Ensembl chrNW_004955541:2,724,312...2,777,592 		JBrowse link
G Ddit4 DNA damage inducible transcript 4 acts_upstream_of_or_within ISO (PMID:20176937) MGI PMID:20176937 NCBI chrNW_004955437:19,322,407...19,324,562
Ensembl chrNW_004955437:19,322,407...19,324,562 		JBrowse link
G Fbp1 fructose-bisphosphatase 1 involved_in ISO (PMID:19881551)
(PMID:25043030)		 UniProt
CAFA		 PMID:19881551 PMID:25043030 NCBI chrNW_004955422:21,537,337...21,569,174
Ensembl chrNW_004955422:21,536,667...21,569,433 		JBrowse link
G Flcn folliculin involved_in ISO (PMID:34381247) UniProt PMID:34381247 NCBI chrNW_004955577:672,774...694,140
Ensembl chrNW_004955577:672,410...694,140 		JBrowse link
G Git1 GIT ArfGAP 1 involved_in ISO (MGI:6478067|PMID:32460388) UniProt PMID:32460388 MGI:6478067 NCBI chrNW_004955481:3,671,728...3,681,279
Ensembl chrNW_004955481:3,670,111...3,685,051 		JBrowse link
G Hdac4 histone deacetylase 4 involved_in ISO (MGI:4365327|PMID:19109424) BHF-UCL PMID:19109424 MGI:4365327 NCBI chrNW_004955542:1,629,691...1,886,160
Ensembl chrNW_004955542:1,629,691...1,886,210 		JBrowse link
G Ier3 immediate early response 3 acts_upstream_of_or_within ISO (PMID:19096392) MGI PMID:19096392 NCBI chrNW_004955583:730,353...731,301
Ensembl chrNW_004955583:730,289...731,260 		JBrowse link
G Mtch2 mitochondrial carrier 2 acts_upstream_of_or_within ISO (PMID:26219591) MGI PMID:26219591 NCBI chrNW_004955422:672,301...690,989
Ensembl chrNW_004955422:672,301...690,989 		JBrowse link
G Myog myogenin ISO RGD PMID:10225962 RGD:9686132 NCBI chrNW_004955406:39,099,044...39,102,479
Ensembl chrNW_004955406:39,099,716...39,102,501 		JBrowse link
G Ncor1 nuclear receptor corepressor 1 involved_in ISO (PMID:19955185) BHF-UCL PMID:19955185 NCBI chrNW_004955467:1,408,292...1,568,539
Ensembl chrNW_004955467:1,409,281...1,546,842 		JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator involved_in ISO (PMID:30451898) UniProt PMID:30451898 NCBI chrNW_004955493:6,746,380...6,747,763
Ensembl chrNW_004955493:6,746,380...6,747,763 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha involved_in ISO (PMID:19955185) BHF-UCL PMID:19955185 NCBI chrNW_004955413:30,306,563...30,366,245
Ensembl chrNW_004955413:30,307,219...30,359,500 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha ISO RGD PMID:22343369 RGD:7242186 NCBI chrNW_004955480:543,397...1,188,376
Ensembl chrNW_004955480:1,078,322...1,188,435 		JBrowse link
G Sik2 salt inducible kinase 2 involved_in ISO (PMID:21084751) MGI PMID:21084751 NCBI chrNW_004955412:13,342,032...13,458,076
Ensembl chrNW_004955412:13,342,032...13,457,563 		JBrowse link
G Sirt6 sirtuin 6 involved_in ISO (MGI:4881401|PMID:20141841), (MGI:5619441|PMID:23217706)
(PMID:26456828)		 CACAO
UniProt		 PMID:20141841 PMID:23217706 PMID:26456828 MGI:4881401 MGI:5619441 NCBI chrNW_004955495:4,641,883...4,650,518
Ensembl chrNW_004955495:4,644,023...4,650,083 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 acts_upstream_of_or_within ISO (PMID:22891351) MGI PMID:22891351 NCBI chrNW_004955451:16,320,326...16,348,505
Ensembl chrNW_004955451:16,319,904...16,357,687 		JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase acts_upstream_of_or_within ISO (PMID:20935145) MGI PMID:20935145 NCBI chrNW_004955413:2,129,719...2,153,873
Ensembl chrNW_004955413:2,129,678...2,154,380 		JBrowse link
G Trim63 tripartite motif containing 63 involved_in ISO (PMID:34244144) FlyBase PMID:34244144 NCBI chrNW_004955452:5,517,969...5,531,490
Ensembl chrNW_004955452:5,520,269...5,531,975 		JBrowse link
negative regulation of glycolytic process through fructose-6-phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pfkfb1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 involved_in ISO (PMID:16155866)
(PMID:15331593)		 MGI PMID:15331593 PMID:16155866 NCBI chrNW_004955475:2,279,390...2,343,881
Ensembl chrNW_004955475:2,279,390...2,342,750 		JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha involved_in ISO (PMID:32192773) MGI PMID:32192773 NCBI chrNW_004955408:5,435,117...5,460,361
Ensembl chrNW_004955408:5,433,268...5,460,361 		JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha involved_in ISO (PMID:16155866)
(PMID:23292513)		 MGI PMID:16155866 PMID:23292513 NCBI chrNW_004955415:32,794,172...32,807,944
Ensembl chrNW_004955415:32,793,718...32,812,930 		JBrowse link
G Slc4a1 solute carrier family 4 member 1 (Diego blood group) acts_upstream_of_or_within ISO (PMID:18698006) MGI PMID:18698006 NCBI chrNW_004955451:17,318,600...17,330,943
Ensembl chrNW_004955451:17,315,024...17,328,103 		JBrowse link
negative regulation of guanylate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hpca hippocalcin ISO RGD PMID:15336960 RGD:9686438 NCBI chrNW_004955452:11,142,282...11,150,798
Ensembl chrNW_004955452:11,140,373...11,154,261 		JBrowse link
G Rd3 RD3 regulator of GUCY2D involved_in ISO (MGI:5810226|PMID:27471269)
(PMID:21928830), (PMID:30559291)		 UniProt PMID:21928830 PMID:27471269 PMID:30559291 MGI:5810226 NCBI chrNW_004955489:896,964...903,855 JBrowse link
negative regulation of pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldob aldolase, fructose-bisphosphate B involved_in ISO (PMID:35122041) UniProt PMID:35122041 NCBI chrNW_004955419:24,377,427...24,389,909
Ensembl chrNW_004955419:24,377,427...24,389,909 		JBrowse link
G Tp53 tumor protein p53 involved_in ISO (PMID:21336310) CACAO PMID:21336310 NCBI chrNW_004955467:9,241,391...9,256,716
Ensembl chrNW_004955467:9,252,130...9,255,928 		JBrowse link
positive regulation of ATP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy10 adenylate cyclase 10 ISO RGD PMID:31172217 RGD:329403053 NCBI chrNW_004955462:9,196,984...9,278,850
Ensembl chrNW_004955462:9,207,314...9,278,621 		JBrowse link
G Bcl2l1 BCL2 like 1 involved_in ISO PMID:23792689 CAFA PMID:23792689 RGD:12793033 NCBI chrNW_004955422:29,254,440...29,307,104
Ensembl chrNW_004955422:29,254,216...29,308,174 		JBrowse link
G Eno1 enolase 1 involved_in ISO (PMID:15459207) CAFA PMID:15459207 NCBI chrNW_004955486:4,275,371...4,287,152
Ensembl chrNW_004955486:4,274,238...4,289,809 		JBrowse link
G Hnf1a HNF1 homeobox A ISO RGD PMID:20841353 RGD:150540305 NCBI chrNW_004955455:10,694,102...10,717,613
Ensembl chrNW_004955455:10,694,102...10,717,613 		JBrowse link
G Il4 interleukin 4 involved_in ISO (MGI:6304699|PMID:29061364) ARUK-UCL PMID:29061364 MGI:6304699 NCBI chrNW_004955408:4,058,052...4,065,999 JBrowse link
G Map2k1 mitogen-activated protein kinase kinase 1 involved_in ISO PMID:15459207 CAFA PMID:15459207 RGD:12793039 NCBI chrNW_004955450:9,181,851...9,205,277
Ensembl chrNW_004955450:9,181,851...9,239,648 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor ISO RGD PMID:22629444 RGD:7240532 NCBI chrNW_004955461:2,714,022...2,718,872
Ensembl chrNW_004955461:2,714,022...2,718,982 		JBrowse link
G Ndufc2 NADH:ubiquinone oxidoreductase subunit C2 ISO RGD PMID:26888427 RGD:11040458 NCBI chrNW_004955414:13,867,880...13,878,040
Ensembl chrNW_004955414:13,867,880...13,878,040 		JBrowse link
G Pid1 phosphotyrosine interaction domain containing 1 involved_in ISO (MGI:5306739|PMID:21080215) BHF-UCL PMID:21080215 MGI:5306739 NCBI chrNW_004955453:5,680,418...5,913,236
Ensembl chrNW_004955453:5,680,211...5,911,589 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha acts_upstream_of ISO (PMID:31574452) ARUK-UCL PMID:31574452 NCBI chrNW_004955413:30,306,563...30,366,245
Ensembl chrNW_004955413:30,307,219...30,359,500 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase ISO RGD PMID:24096089 RGD:10413842 NCBI chrNW_004955439:18,664,230...19,953,358
Ensembl chrNW_004955439:18,664,379...19,951,152 		JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (PMID:24747689) AgBase PMID:24747689 NCBI chrNW_004955425:20,280,725...20,307,663
Ensembl chrNW_004955425:20,279,963...20,307,663 		JBrowse link
G Slc25a12 solute carrier family 25 member 12 ISO RGD PMID:19764902 RGD:13628741 NCBI chrNW_004955449:3,093,603...3,182,513
Ensembl chrNW_004955449:3,093,603...3,186,737 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO RGD PMID:23590160 RGD:8694322 NCBI chrNW_004955451:16,320,326...16,348,505
Ensembl chrNW_004955451:16,319,904...16,357,687 		JBrowse link
G Tafazzin tafazzin, phospholipid-lysophospholipid transacylase ISO RGD PMID:20348225 RGD:13432160 NCBI chrNW_004955580:915,668...921,703
Ensembl chrNW_004955580:915,188...922,791 		JBrowse link
G Tmsb4x thymosin beta 4 X-linked involved_in ISO (PMID:21106936) CAFA PMID:21106936 NCBI chrNW_004955544:266,397...268,447
Ensembl chrNW_004955544:266,397...268,447 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (MGI:5906931|PMID:28802038) ARUK-UCL PMID:28802038 MGI:5906931 NCBI chrNW_004955437:7,780,886...7,785,597
Ensembl chrNW_004955437:7,780,679...7,785,697 		JBrowse link
G Vcp valosin containing protein involved_in ISO (PMID:23498975) ParkinsonsUK-UCL PMID:23498975 NCBI chrNW_004955472:1,111,649...1,124,076
Ensembl chrNW_004955472:1,107,164...1,124,076 		JBrowse link
positive regulation of ATP metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bend3 BEN domain containing 3 involved_in ISO (PMID:28977671) UniProt PMID:28977671 NCBI chrNW_004955411:32,346,573...32,384,796
Ensembl chrNW_004955411:32,345,577...32,384,796 		JBrowse link
positive regulation of glycolytic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein involved_in ISO (PMID:29061364) ARUK-UCL PMID:29061364 NCBI chrNW_004955407:25,725,259...25,973,582
Ensembl chrNW_004955407:25,722,849...25,974,268 		JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator acts_upstream_of ISO (PMID:8089148) BHF-UCL PMID:8089148 NCBI chrNW_004955588:159,462...233,047
Ensembl chrNW_004955588:159,462...233,047 		JBrowse link
G Esrrb estrogen related receptor beta involved_in ISO PMID:24481529 BHF-UCL PMID:24481529 RGD:12910990 NCBI chrNW_004955438:365,375...534,086
Ensembl chrNW_004955438:365,137...534,666 		JBrowse link
G Gck glucokinase ISO RGD PMID:17553851 RGD:2301905 NCBI chrNW_004955456:7,784,269...7,838,260
Ensembl chrNW_004955456:7,783,760...7,842,129 		JBrowse link
G Gpd1 glycerol-3-phosphate dehydrogenase 1 acts_upstream_of_or_within ISO (PMID:11147825) MGI PMID:11147825 NCBI chrNW_004955547:676,661...683,906
Ensembl chrNW_004955547:676,342...690,777 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha acts_upstream_of ISO (PMID:8089148) BHF-UCL PMID:8089148 NCBI chrNW_004955466:8,000,311...8,022,497
Ensembl chrNW_004955466:8,000,044...8,022,497 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A acts_upstream_of_or_within ISO (PMID:17408640) MGI PMID:17408640 NCBI chrNW_004955431:583,165...646,991
Ensembl chrNW_004955431:580,713...647,345 		JBrowse link
G Ifng interferon gamma involved_in ISO (MGI:6304699|PMID:29061364) ARUK-UCL PMID:29061364 MGI:6304699 NCBI chrNW_004955458:14,643,333...14,648,020
Ensembl chrNW_004955458:14,643,313...14,648,045 		JBrowse link
G Igf1 insulin like growth factor 1 involved_in ISO (PMID:7688386) BHF-UCL PMID:7688386 NCBI chrNW_004955405:37,505,830...37,582,152
Ensembl chrNW_004955405:37,512,201...37,582,152 		JBrowse link
G Ins insulin involved_in ISO (PMID:381941)
(PMID:7688386)		 BHF-UCL PMID:381941 PMID:7688386 NCBI chrNW_004955422:13,909,408...13,910,419
Ensembl chrNW_004955422:13,909,407...13,910,419 		JBrowse link
G Insr insulin receptor involved_in ISO (PMID:7693131) BHF-UCL PMID:7693131 NCBI chrNW_004955563:1,867,400...2,011,845
Ensembl chrNW_004955563:1,867,400...2,009,149 		JBrowse link
G Kat2b lysine acetyltransferase 2B involved_in ISO (PMID:21084751) MGI PMID:21084751 NCBI chrNW_004955430:12,109,493...12,196,102
Ensembl chrNW_004955430:12,128,069...12,198,117 		JBrowse link
G Mif macrophage migration inhibitory factor ISO RGD PMID:11086030 RGD:1642010 NCBI chrNW_004955455:8,367,566...8,368,460
Ensembl chrNW_004955455:8,367,566...8,368,460 		JBrowse link
G Mlx MAX dimerization protein MLX involved_in ISO (PMID:14742444) MGI PMID:14742444 NCBI chrNW_004955451:16,460,737...16,464,529
Ensembl chrNW_004955451:16,459,879...16,464,529 		JBrowse link
G Mlxipl MLX interacting protein like involved_in ISO (PMID:19995986)
(PMID:14742444)
(MGI:3041761|PMID:15118080)		 BHF-UCL
MGI		 PMID:14742444 PMID:15118080 PMID:19995986 MGI:3041761 NCBI chrNW_004955456:14,096,530...14,116,687
Ensembl chrNW_004955456:14,096,531...14,117,269 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor ISO RGD PMID:22842522 RGD:7207891 NCBI chrNW_004955461:2,714,022...2,718,872
Ensembl chrNW_004955461:2,714,022...2,718,982 		JBrowse link
G P2rx7 purinergic receptor P2X 7 involved_in ISO (PMID:22898868) CACAO PMID:22898868 NCBI chrNW_004955482:7,048,674...7,087,525
Ensembl chrNW_004955482:7,048,776...7,086,926 		JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 involved_in ISO PMID:11069105 UniProt PMID:11069105 RGD:8554193 NCBI chrNW_004955426:25,079,718...25,102,090
Ensembl chrNW_004955426:25,079,718...25,102,090 		JBrowse link
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 involved_in ISO PMID:11069105 UniProt PMID:11069105 RGD:8554193 NCBI chrNW_004955464:2,996,608...3,062,197
Ensembl chrNW_004955464:3,003,837...3,062,197 		JBrowse link
G Psen1 presenilin 1 involved_in ISO (PMID:29061364) ARUK-UCL PMID:29061364 NCBI chrNW_004955523:2,128,529...2,210,737
Ensembl chrNW_004955523:2,128,529...2,210,737 		JBrowse link
G Slc4a4 solute carrier family 4 member 4 acts_upstream_of ISO (PMID:21976511)
(MGI:5295108|PMID:21976511)		 ARUK-UCL PMID:21976511 MGI:5295108 NCBI chrNW_004955447:1,599,986...1,900,791
Ensembl chrNW_004955447:1,599,929...1,900,791 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in ISO (PMID:35263589) UniProt PMID:35263589 NCBI chrNW_004955445:19,213,210...19,227,670
Ensembl chrNW_004955445:19,215,161...19,228,695 		JBrowse link
G Uchl1 ubiquitin C-terminal hydrolase L1 involved_in ISO (PMID:34244144) FlyBase PMID:34244144 NCBI chrNW_004955443:6,367,519...6,379,638
Ensembl chrNW_004955443:6,367,460...6,380,462 		JBrowse link
G Zbtb20 zinc finger and BTB domain containing 20 involved_in ISO (MGI:5913553|PMID:28327662) UniProt PMID:28327662 MGI:5913553 NCBI chrNW_004955427:14,409,700...15,231,495
Ensembl chrNW_004955427:14,409,700...14,453,926 		JBrowse link
positive regulation of glycolytic process through fructose-6-phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pfkfb1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 involved_in ISO PMID:12230553 FlyBase PMID:12230553 RGD:405650381 NCBI chrNW_004955475:2,279,390...2,343,881
Ensembl chrNW_004955475:2,279,390...2,342,750 		JBrowse link
positive regulation of guanylate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2b adenosine A2b receptor acts_upstream_of_or_within ISO (PMID:18340377) MGI PMID:18340377 NCBI chrNW_004955467:1,342,271...1,363,149
Ensembl chrNW_004955467:1,342,271...1,363,138 		JBrowse link
G Guca1a guanylate cyclase activator 1A ISO RGD PMID:12545196 RGD:1599357 NCBI chrNW_004955437:8,370,553...8,382,640
Ensembl chrNW_004955437:8,376,091...8,382,640 		JBrowse link
G Nos3 nitric oxide synthase 3 involved_in ISO (PMID:17502619) BHF-UCL PMID:17502619 NCBI chrNW_004955491:5,438,228...5,457,308
Ensembl chrNW_004955491:5,438,010...5,460,814 		JBrowse link
positive regulation of pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tigar TP53 induced glycolysis regulatory phosphatase involved_in ISO (MGI:5574521|PMID:24872551) UniProt PMID:24872551 MGI:5574521 NCBI chrNW_004955413:2,129,719...2,153,873
Ensembl chrNW_004955413:2,129,678...2,154,380 		JBrowse link
regulation of acetyl-CoA biosynthetic process from pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdk1 pyruvate dehydrogenase kinase 1 involved_in ISO (MGI:5487511|PMID:22195962) UniProt PMID:22195962 MGI:5487511 NCBI chrNW_004955449:2,546,790...2,582,402
Ensembl chrNW_004955449:2,549,139...2,582,243 		JBrowse link
G Pdk2 pyruvate dehydrogenase kinase 2 involved_in ISO (MGI:5428826|PMID:22360721) UniProt PMID:22360721 MGI:5428826 NCBI chrNW_004955451:11,547,660...11,559,266
Ensembl chrNW_004955451:11,547,660...11,559,403 		JBrowse link
G Pdk3 pyruvate dehydrogenase kinase 3 involved_in ISO (PMID:22865452) UniProt PMID:22865452 NCBI chrNW_004955509:4,809,422...4,888,802
Ensembl chrNW_004955509:4,809,399...4,878,976 		JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 involved_in ISO (PMID:21852536)
(MGI:3692363|PMID:16606348)		 UniProt PMID:16606348 PMID:21852536 MGI:3692363 NCBI chrNW_004955432:12,169,548...12,182,064
Ensembl chrNW_004955432:12,169,435...12,182,409 		JBrowse link
G Tpk1 thiamin pyrophosphokinase 1 involved_in ISO (PMID:38547260) UniProt PMID:38547260 NCBI chrNW_004955491:621,941...968,570
Ensembl chrNW_004955491:623,530...968,253 		JBrowse link
regulation of acyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Snca synuclein alpha acts_upstream_of_or_within ISO (PMID:16636270)
(PMID:16734431)		 MGI PMID:16636270 PMID:16734431 NCBI chrNW_004955405:854,011...962,741
Ensembl chrNW_004955405:853,946...965,403 		JBrowse link
regulation of ATP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sphk2 sphingosine kinase 2 involved_in ISO (MGI:5641585|PMID:25637806) UniProt PMID:25637806 MGI:5641585 NCBI chrNW_004955559:1,921,479...1,929,450
Ensembl chrNW_004955559:1,917,301...1,928,493 		JBrowse link
regulation of ATP metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp5if1 ATP synthase inhibitory factor subunit 1 involved_in ISO (PMID:24005319) ParkinsonsUK-UCL PMID:24005319 NCBI chrNW_004955452:7,372,917...7,375,072
Ensembl chrNW_004955452:7,373,001...7,375,856 		JBrowse link
G Dnm1l dynamin 1 like involved_in ISO (MGI:4459561|PMID:20585624) ParkinsonsUK-UCL PMID:20585624 MGI:4459561 NCBI chrNW_004955505:3,025,742...3,081,491
Ensembl chrNW_004955505:3,023,018...3,081,680 		JBrowse link
regulation of glycolytic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arl2 ADP ribosylation factor like GTPase 2 involved_in ISO (PMID:30945270) UniProt PMID:30945270 NCBI chrNW_004955422:20,166,956...20,172,954
Ensembl chrNW_004955422:20,166,956...20,172,950 		JBrowse link
G Eif6 eukaryotic translation initiation factor 6 involved_in ISO (MGI:5699484|PMID:26383020) UniProt PMID:26383020 MGI:5699484 NCBI chrNW_004956210:226...6,819
Ensembl chrNW_004956210:21...9,816 		JBrowse link
G Ep300 E1A binding protein p300 involved_in ISO (PMID:29775581) UniProt PMID:29775581 NCBI chrNW_004955413:26,647,553...26,727,875
Ensembl chrNW_004955413:26,648,339...26,727,933 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha involved_in
acts_upstream_of_or_within		 ISO (PMID:32697943)
(PMID:17437992)		 UniProt
MGI		 PMID:17437992 PMID:32697943 NCBI chrNW_004955466:8,000,311...8,022,497
Ensembl chrNW_004955466:8,000,044...8,022,497 		JBrowse link
G Jmjd8 jumonji domain containing 8 involved_in ISO (PMID:27199445) UniProt PMID:27199445 NCBI chrNW_004955442:16,519,394...16,521,106
Ensembl chrNW_004955442:16,519,397...16,521,106 		JBrowse link
G Mlxipl MLX interacting protein like ISO RGD PMID:11724780 RGD:634534 NCBI chrNW_004955456:14,096,530...14,116,687
Ensembl chrNW_004955456:14,096,531...14,117,269 		JBrowse link
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase involved_in ISO (PMID:22923583) UniProt PMID:22923583 NCBI chrNW_004955475:11,062,258...11,112,252
Ensembl chrNW_004955475:11,062,076...11,114,169 		JBrowse link
G Prkag2 protein kinase AMP-activated non-catalytic subunit gamma 2 involved_in ISO (PMID:15877279) BHF-UCL PMID:15877279 NCBI chrNW_004955491:5,852,534...6,048,820
Ensembl chrNW_004955491:5,852,082...6,019,318 		JBrowse link
G Prkag3 protein kinase AMP-activated non-catalytic subunit gamma 3 acts_upstream_of_or_within ISO (PMID:15857891) MGI PMID:15857891 NCBI chrNW_004955453:14,584,405...14,594,112
Ensembl chrNW_004955453:14,584,412...14,595,369 		JBrowse link
G Slc2a6 solute carrier family 2 member 6 involved_in ISO (PMID:30431159)
(MGI:6276413|PMID:30431159)		 UniProt PMID:30431159 MGI:6276413 NCBI chrNW_004955513:2,796,086...2,802,051
Ensembl chrNW_004955513:2,796,531...2,802,054 		JBrowse link
G Trex1 three prime repair exonuclease 1 acts_upstream_of_or_within ISO (PMID:28069950) MGI PMID:28069950 NCBI chrNW_004955532:533,877...535,767
Ensembl chrNW_004955532:533,877...535,767 		JBrowse link
G Zbtb7a zinc finger and BTB domain containing 7A involved_in ISO (PMID:26455326) UniProt PMID:26455326 NCBI chrNW_004955495:4,747,905...4,754,066
Ensembl chrNW_004955495:4,740,901...4,753,992 		JBrowse link
regulation of guanylate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Guca1a guanylate cyclase activator 1A acts_upstream_of_or_within ISO (PMID:15336959) MGI PMID:15336959 NCBI chrNW_004955437:8,370,553...8,382,640
Ensembl chrNW_004955437:8,376,091...8,382,640 		JBrowse link
G Guca1b guanylate cyclase activator 1B acts_upstream_of_or_within ISO (PMID:15336959) MGI PMID:15336959 NCBI chrNW_004955437:8,384,692...8,390,946
Ensembl chrNW_004955437:8,382,299...8,390,946 		JBrowse link
regulation of mitochondrial ATP synthesis coupled proton transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atpsckmt ATP synthase c subunit lysine N-methyltransferase involved_in ISO (PMID:30530489)
(MGI:6277238|PMID:30530489)		 UniProt PMID:30530489 MGI:6277238 NCBI chrNW_004955426:116,223...131,798
Ensembl chrNW_004955426:116,514...126,244 		JBrowse link
G Dnajc30 DnaJ heat shock protein family (Hsp40) member C30 involved_in ISO (MGI:6245118|PMID:30318146) UniProt PMID:30318146 MGI:6245118 NCBI chrNW_004955456:14,057,517...14,058,729
Ensembl chrNW_004955456:14,057,620...14,058,303 		JBrowse link
regulation of NAD metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC102008188 core histone macro-H2A.1 involved_in ISO (PMID:28991266) UniProt PMID:28991266 NCBI chrNW_004955408:30,497,531...30,550,095
Ensembl chrNW_004955408:30,497,531...30,550,118 		JBrowse link
regulation of NADP metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hnf1a HNF1 homeobox A ISO RGD PMID:20841353 RGD:150540305 NCBI chrNW_004955455:10,694,102...10,717,613
Ensembl chrNW_004955455:10,694,102...10,717,613 		JBrowse link
G Me1 malic enzyme 1 involved_in ISO (PMID:23334421) CACAO PMID:23334421 NCBI chrNW_004955411:10,938,580...11,084,171
Ensembl chrNW_004955411:10,938,944...11,065,085 		JBrowse link
G Me2 malic enzyme 2 involved_in ISO (PMID:23334421) CACAO PMID:23334421 NCBI chrNW_004955402:35,816,474...35,894,051 JBrowse link
regulation of pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 ISO RGD PMID:16234247 RGD:1625062 NCBI chrNW_004955489:2,500,928...2,524,715
Ensembl chrNW_004955489:2,497,680...2,524,805 		JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase involved_in ISO (PMID:25928429) UniProt PMID:25928429 NCBI chrNW_004955413:2,129,719...2,153,873
Ensembl chrNW_004955413:2,129,678...2,154,380 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12483
    metabolic process 7922
      purine-containing compound metabolic process 403
        purine nucleotide metabolic process 374
          regulation of purine nucleotide metabolic process 101
            negative regulation of purine nucleotide metabolic process + 32
            positive regulation of purine nucleotide metabolic process + 47
            regulation of ATP metabolic process + 82
            regulation of NAD metabolic process + 1
            regulation of NADP metabolic process + 7
            regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway + 0
            regulation of purine nucleotide biosynthetic process + 35
            regulation of purine nucleotide catabolic process + 57
            regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA + 0
Path 2
Term Annotations click to browse term
  biological_process 12483
    biological regulation 9026
      regulation of biological process 8728
        regulation of cellular process 8268
          regulation of cellular metabolic process 4489
            regulation of phosphorus metabolic process 1094
              regulation of phosphate metabolic process 1090
                regulation of nucleotide metabolic process 102
                  regulation of purine nucleotide metabolic process 101
                    negative regulation of purine nucleotide metabolic process + 32
                    positive regulation of purine nucleotide metabolic process + 47
                    regulation of ATP metabolic process + 82
                    regulation of NAD metabolic process + 1
                    regulation of NADP metabolic process + 7
                    regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway + 0
                    regulation of purine nucleotide biosynthetic process + 35
                    regulation of purine nucleotide catabolic process + 57
                    regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA + 0
paths to the root