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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of RNA-directed 5'-3' RNA polymerase activity
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Accession:GO:1900260 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of RNA-directed 5'-3' RNA polymerase activity.
Synonyms:exact_synonym: down regulation of 3D polymerase activity;   down regulation of Q-beta replicase activity;   down regulation of RNA nucleotidyltransferase (RNA-directed) activity;   down regulation of RNA replicase activity;   down regulation of RNA-dependent RNA polymerase activity;   down regulation of RNA-dependent RNA replicase activity;   down regulation of RNA-dependent ribonucleate nucleotidyltransferase activity;   down regulation of RNA-directed RNA polymerase activity;   down regulation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed);   down regulation of ribonucleic acid replicase activity;   down regulation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity;   down regulation of ribonucleic acid-dependent ribonucleic acid polymerase activity;   down regulation of ribonucleic replicase activity;   downregulation of 3D polymerase activity;   downregulation of Q-beta replicase activity;   downregulation of RNA nucleotidyltransferase (RNA-directed) activity;   downregulation of RNA replicase activity;   downregulation of RNA-dependent RNA polymerase activity;   downregulation of RNA-dependent RNA replicase activity;   downregulation of RNA-dependent ribonucleate nucleotidyltransferase activity;   downregulation of RNA-directed RNA polymerase activity;   downregulation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed);   downregulation of ribonucleic acid replicase activity;   downregulation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity;   downregulation of ribonucleic acid-dependent ribonucleic acid polymerase activity;   downregulation of ribonucleic replicase activity;   inhibition of 3D polymerase activity;   inhibition of Q-beta replicase activity;   inhibition of RNA nucleotidyltransferase (RNA-directed) activity;   inhibition of RNA replicase activity;   inhibition of RNA-dependent RNA polymerase activity;   inhibition of RNA-dependent RNA replicase activity;   inhibition of RNA-dependent ribonucleate nucleotidyltransferase activity;   inhibition of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed);   inhibition of ribonucleic acid replicase activity;   inhibition of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity;   inhibition of ribonucleic acid-dependent ribonucleic acid polymerase activity;   inhibition of ribonucleic replicase activity;   negative regulation of 3D polymerase activity;   negative regulation of Q-beta replicase activity;   negative regulation of RNA nucleotidyltransferase (RNA-directed) activity;   negative regulation of RNA replicase activity;   negative regulation of RNA-dependent RNA polymerase activity;   negative regulation of RNA-dependent RNA replicase activity;   negative regulation of RNA-dependent ribonucleate nucleotidyltransferase activity;   negative regulation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed);   negative regulation of ribonucleic acid replicase activity;   negative regulation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity;   negative regulation of ribonucleic acid-dependent ribonucleic acid polymerase activity;   negative regulation of ribonucleic replicase activity
 narrow_synonym: down regulation of phage f2 replicase;   downregulation of phage f2 replicase;   inhibition of RNA-directed RNA polymerase activity;   inhibition of phage f2 replicase;   negative regulation of phage f2 replicase
 broad_synonym: down regulation of transcriptase;   downregulation of transcriptase;   inhibition of transcriptase;   negative regulation of RNA-directed RNA polymerase activity;   negative regulation of transcriptase
 related_synonym: down regulation of PB1 proteins;   down regulation of PB2 proteins;   down regulation of RDRP;   down regulation of RNA synthetase activity;   down regulation of polymerase L;   down regulation of ribonucleic synthetase activity;   downregulation of PB1 proteins;   downregulation of PB2 proteins;   downregulation of RDRP;   downregulation of RNA synthetase activity;   downregulation of polymerase L;   downregulation of ribonucleic synthetase activity;   inhibition of PB1 proteins;   inhibition of PB2 proteins;   inhibition of RDRP;   inhibition of RNA synthetase activity;   inhibition of polymerase L;   inhibition of ribonucleic synthetase activity;   negative regulation of PB1 proteins;   negative regulation of PB2 proteins;   negative regulation of RDRP;   negative regulation of RNA synthetase activity;   negative regulation of polymerase L;   negative regulation of ribonucleic synthetase activity


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negative regulation of RNA-directed 5'-3' RNA polymerase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif4a2 eukaryotic translation initiation factor 4A2 ISO (PMID:11922617) RGD PMID:11922617 NCBI chr11:81,373,047...81,379,680
Ensembl chr11:81,373,048...81,379,871
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  biological_process 20030
    biological regulation 13774
      regulation of molecular function 3073
        negative regulation of molecular function 1227
          negative regulation of catalytic activity 855
            negative regulation of transferase activity 291
              negative regulation of RNA-directed 5'-3' RNA polymerase activity 1
Path 2
Term Annotations click to browse term
  biological_process 20030
    metabolic process 12185
      cellular metabolic process 10964
        cellular aromatic compound metabolic process 5688
          nucleobase-containing compound metabolic process 5476
            nucleic acid metabolic process 4972
              RNA metabolic process 4456
                regulation of RNA metabolic process 3599
                  regulation of RNA biosynthetic process 3326
                    regulation of nucleic acid-templated transcription 3321
                      negative regulation of nucleic acid-templated transcription 1376
                        negative regulation of RNA-directed 5'-3' RNA polymerase activity 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.