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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of NLRP3 inflammasome complex assembly
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Accession:GO:1900225 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of NLRP3 inflammasome complex assembly.
Synonyms:exact_synonym: regulation of NALP3 inflammasome complex assembly
 related_synonym: regulation of NLRP3 inflammasome activation



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regulation of NLRP3 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:5432942|PMID:22801494)
UniProt
RGD
PMID:22801494 GO_REF:0000024 MGI:5432942 NCBI chr 6:16,189,000...16,224,972
Ensembl chr 6:16,188,979...16,224,971
JBrowse link
negative regulation of NLRP3 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cptp ceramide-1-phosphate transfer protein involved_in ISO
ISS
(PMID:29164996)
GO_REF:0000024
RGD
UniProt
PMID:29164996 GO_REF:0000024 NCBI chr 5:166,474,947...166,479,103
Ensembl chr 5:166,474,966...166,479,017
JBrowse link
G Mefv MEFV innate immuity regulator, pyrin involved_in ISS
ISO
GO_REF:0000024
(PMID:26347139)
UniProt
RGD
PMID:26347139 GO_REF:0000024 NCBI chr10:11,786,948...11,796,977
Ensembl chr10:11,787,422...11,796,973
JBrowse link
G Nlrc3 NLR family, CARD domain containing 3 involved_in ISO (PMID:25277106) RGD PMID:25277106 NCBI chr10:11,551,378...11,585,027
Ensembl chr10:11,551,356...11,584,398
JBrowse link
G Nlrp1b NLR family, pyrin domain containing 1B involved_in ISO (PMID:24517500) RGD PMID:24517500 NCBI chr10:55,838,381...55,904,374 JBrowse link
G Sirt2 sirtuin 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:5488534|PMID:23502856)
Ensembl
RGD
PMID:23502856 GO_REF:0000107 MGI:5488534 NCBI chr 1:84,053,883...84,076,975
Ensembl chr 1:84,052,903...84,076,975
JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 acts_upstream_of_or_within ISO (MGI:6391726|PMID:29887864)
(PMID:32514138)
RGD PMID:29887864 PMID:32514138 MGI:6391726 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170
JBrowse link
positive regulation of NLRP3 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atat1 alpha tubulin acetyltransferase 1 acts_upstream_of_or_within ISO (MGI:5488534|PMID:23502856) RGD PMID:23502856 MGI:5488534 NCBI chr20:2,844,595...2,857,809
Ensembl chr20:2,844,616...2,861,964
JBrowse link
G Cd36 CD36 molecule involved_in ISS
ISO
GO_REF:0000024
(MGI:5546292|PMID:23812099)
UniProt
RGD
PMID:23812099 GO_REF:0000024 MGI:5546292 NCBI chr 4:17,317,343...17,410,084 JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked involved_in ISO (MGI:6368386|PMID:31511697) RGD PMID:31511697 MGI:6368386 NCBI chr  X:9,479,532...9,493,455
Ensembl chr  X:9,479,532...9,493,168
JBrowse link
G Dhx33 DEAH-box helicase 33 involved_in ISO (PMID:23871209) RGD PMID:23871209 NCBI chr10:55,708,102...55,724,618
Ensembl chr10:55,705,756...55,724,567
JBrowse link
G Gbp5 guanylate binding protein 5 involved_in ISO (PMID:22461501) RGD PMID:22461501 NCBI chr 2:231,237,748...231,257,071
Ensembl chr 2:231,237,748...231,257,061
JBrowse link
G Mir21 microRNA 21 IDA RGD PMID:29084974 RGD:41404715 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor involved_in ISS
ISO
GO_REF:0000024
(PMID:33718825)
UniProt
RGD
PMID:33718825 GO_REF:0000024 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415
JBrowse link
G Plcg2 phospholipase C, gamma 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:32514138)
GO_REF:0000107
RGD
Ensembl
PMID:32514138 GO_REF:0000107 NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930
JBrowse link
G Stmp1 short transmembrane mitochondrial protein 1 involved_in ISO (MGI:6384515|PMID:31836654) RGD PMID:31836654 MGI:6384515 NCBI chr 4:63,927,523...63,937,355 JBrowse link
G Tlr4 toll-like receptor 4 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:5546292|PMID:23812099)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:23812099 GO_REF:0000024 GO_REF:0000107 MGI:5546292 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tlr6 toll-like receptor 6 involved_in ISO (MGI:5546292|PMID:23812099) RGD PMID:23812099 MGI:5546292 NCBI chr14:43,362,164...43,374,500
Ensembl chr14:43,362,164...43,375,685
JBrowse link
G Usp50 ubiquitin specific peptidase 50 acts_upstream_of_or_within ISO (MGI:5888801|PMID:28094437)
(PMID:28094437)
RGD PMID:28094437 MGI:5888801 NCBI chr 3:114,012,104...114,035,468
Ensembl chr 3:114,011,702...114,035,476
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19390
    regulation of biological process 12735
      regulation of cellular process 12196
        regulation of cellular component organization 2451
          regulation of protein-containing complex assembly 432
            regulation of NLRP3 inflammasome complex assembly 19
              negative regulation of NLRP3 inflammasome complex assembly 6
              positive regulation of NLRP3 inflammasome complex assembly 12
Path 2
Term Annotations click to browse term
  biological_process 19390
    cellular process 18252
      cellular component organization or biogenesis 6492
        cellular component organization 6250
          protein-containing complex subunit organization 1756
            protein-containing complex assembly 1550
              cellular protein-containing complex assembly 1066
                inflammasome complex assembly 22
                  NLRP3 inflammasome complex assembly 21
                    regulation of NLRP3 inflammasome complex assembly 19
                      negative regulation of NLRP3 inflammasome complex assembly 6
                      positive regulation of NLRP3 inflammasome complex assembly 12
paths to the root