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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of amyloid-beta clearance
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Accession:GO:1900221 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of amyloid-beta clearance.


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regulation of amyloid-beta clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in ISO
IEA
IBA
(PMID:24446231)
GO_REF:0000107
PMID:21873635
RGD
Ensembl
PMID:24446231 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G App amyloid beta precursor protein acts_upstream_of ISO (PMID:19057576) RGD PMID:19057576 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Clu clusterin involved_in ISO
ISS
IEA
(PMID:24446231)
GO_REF:0000024
GO_REF:0000107
RGD
Alzheimers_University_of_Toronto
Ensembl
PMID:24446231 GO_REF:0000024 GO_REF:0000107 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
JBrowse link
negative regulation of amyloid-beta clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp51 cytochrome P450, family 51 involved_in ISO (MGI:6270905|PMID:20876579) RGD PMID:20876579 MGI:6270905 NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase involved_in ISO (MGI:6270905|PMID:20876579) RGD PMID:20876579 MGI:6270905 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Ifng interferon gamma involved_in ISO UniProtKB:P06804|UniProtKB:P15261 (MGI:3697769|PMID:17255335), (MGI:6304699|PMID:29061364) RGD PMID:17255335 PMID:29061364 MGI:3697769 MGI:6304699 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Ifngr1 interferon gamma receptor 1 involved_in ISO UniProtKB:P01580|UniProtKB:P06804 (MGI:3697769|PMID:17255335) RGD PMID:17255335 MGI:3697769 NCBI chr 1:14,333,167...14,351,799
Ensembl chr 1:14,333,187...14,351,785
JBrowse link
G Lrpap1 LDL receptor related protein associated protein 1 involved_in ISO UniProtKB:Q07954 (PMID:19098903) RGD PMID:19098903 NCBI chr14:75,651,371...75,663,380
Ensembl chr14:75,651,376...75,665,414
JBrowse link
G Myocd myocardin involved_in IEA
ISO
GO_REF:0000107
(PMID:19098903)
Ensembl
RGD
PMID:19098903 GO_REF:0000107 NCBI chr10:49,833,219...49,928,806
Ensembl chr10:49,836,641...49,927,627
JBrowse link
G Pla2g3 phospholipase A2, group III acts_upstream_of_or_within ISO (MGI:5912601|PMID:26637123) RGD PMID:26637123 MGI:5912601 NCBI chr14:78,367,625...78,373,913
Ensembl chr14:78,368,105...78,373,913
JBrowse link
G Srf serum response factor involved_in ISO (PMID:19098903) RGD PMID:19098903 NCBI chr 9:14,426,453...14,435,734
Ensembl chr 9:14,426,472...14,435,733
JBrowse link
G Tnf tumor necrosis factor involved_in ISO UniProtKB:P01580|UniProtKB:P15261 (MGI:3697769|PMID:17255335) RGD PMID:17255335 MGI:3697769 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
positive regulation of amyloid-beta clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca7 ATP binding cassette subfamily A member 7 involved_in ISS
ISO
GO_REF:0000024
(MGI:5487687|PMID:23467355)
Alzheimers_University_of_Toronto
RGD
PMID:23467355 GO_REF:0000024 MGI:5487687 NCBI chr 7:9,691,452...9,711,466
Ensembl chr 7:9,691,449...9,711,425
JBrowse link
G Apoe apolipoprotein E involved_in ISS
ISO
GO_REF:0000024
(MGI:3621689|PMID:14741101)
UniProt
RGD
PMID:14741101 GO_REF:0000024 MGI:3621689 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Il4 interleukin 4 involved_in IDA
ISO
IBA
PMID:18941241
(MGI:6272248|PMID:18941241)
PMID:21873635
RGD PMID:18941241 PMID:18941241 PMID:21873635 MGI:6272248, RGD:13825436, RGD:13792537 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Lrp1 LDL receptor related protein 1 involved_in ISO (MGI:5754651|PMID:26619118) RGD PMID:26619118 MGI:5754651 NCBI chr 7:63,380,325...63,461,029
Ensembl chr 7:63,380,356...63,460,910
JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 involved_in ISO
IEA
UniProtKB:Q14457 (PMID:27853422)
GO_REF:0000107
RGD
Ensembl
PMID:27853422 GO_REF:0000107 NCBI chr18:1,114,532...1,236,345
Ensembl chr18:1,115,905...1,235,571
JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:31235932)
(MGI:5906931|PMID:28802038), (MGI:6254954|PMID:26949937), (MGI:6313424|PMID:30617257), (MGI:6378367|PMID:31235932)
RGD PMID:26949937 PMID:28802038 PMID:30617257 PMID:31235932 MGI:5906931 MGI:6254954 MGI:6313424 MGI:6378367 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170
JBrowse link
G Ttpa alpha tocopherol transfer protein acts_upstream_of_or_within ISO MGI:2386172 (MGI:5912601|PMID:26637123) RGD PMID:26637123 MGI:5912601 NCBI chr 5:33,497,537...33,518,936
Ensembl chr 5:33,497,137...33,518,073
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    multicellular organismal process 8823
      regulation of multicellular organismal process 2920
        regulation of amyloid-beta clearance 18
          negative regulation of amyloid-beta clearance 9
          positive regulation of amyloid-beta clearance 7
Path 2
Term Annotations click to browse term
  biological_process 19492
    biological regulation 13513
      regulation of biological process 12769
        regulation of multicellular organismal process 2920
          regulation of amyloid-beta clearance 18
            negative regulation of amyloid-beta clearance 9
            positive regulation of amyloid-beta clearance 7
paths to the root