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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
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Accession:GO:1900153 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay.
Synonyms:exact_synonym: positive regulation of deadenylation-dependent mRNA decay;   positive regulation of mRNA breakdown, deadenylation-dependent decay;   positive regulation of mRNA catabolic process, deadenylation-dependent;   positive regulation of mRNA catabolic process, deadenylylation-dependent;   positive regulation of mRNA catabolism, deadenylation-dependent;   positive regulation of mRNA catabolism, deadenylylation-dependent;   positive regulation of mRNA degradation, deadenylation-dependent decay;   positive regulation of nuclear mRNA catabolic process, deadenylation-dependent decay;   up regulation of deadenylation-dependent mRNA decay;   up regulation of mRNA breakdown, deadenylation-dependent decay;   up regulation of mRNA catabolic process, deadenylation-dependent;   up regulation of mRNA catabolic process, deadenylylation-dependent;   up regulation of mRNA catabolism, deadenylation-dependent;   up regulation of mRNA catabolism, deadenylylation-dependent;   up regulation of mRNA degradation, deadenylation-dependent decay;   up regulation of nuclear mRNA catabolic process, deadenylation-dependent decay;   up regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;   upregulation of deadenylation-dependent mRNA decay;   upregulation of mRNA breakdown, deadenylation-dependent decay;   upregulation of mRNA catabolic process, deadenylation-dependent;   upregulation of mRNA catabolic process, deadenylylation-dependent;   upregulation of mRNA catabolism, deadenylation-dependent;   upregulation of mRNA catabolism, deadenylylation-dependent;   upregulation of mRNA degradation, deadenylation-dependent decay;   upregulation of nuclear mRNA catabolic process, deadenylation-dependent decay;   upregulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
 narrow_synonym: activation of deadenylation-dependent mRNA decay;   activation of mRNA breakdown, deadenylation-dependent decay;   activation of mRNA catabolic process, deadenylation-dependent;   activation of mRNA catabolic process, deadenylylation-dependent;   activation of mRNA catabolism, deadenylation-dependent;   activation of mRNA catabolism, deadenylylation-dependent;   activation of mRNA degradation, deadenylation-dependent decay;   activation of nuclear mRNA catabolic process, deadenylation-dependent decay;   activation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay


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positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGO2 argonaute RISC catalytic component 2 ISO (MGI:MGI:5486537|PMID:19716330) UniProtKB PMID:19716330 MGI:MGI:5486537 NCBI chr13:35,169,243...35,230,252
Ensembl chr13:35,180,912...35,268,577
JBrowse link
G CNOT1 CCR4-NOT transcription complex subunit 1 ISO (PMID:21278420) UniProtKB PMID:21278420 NCBI chr 2:58,038,456...58,138,364
Ensembl chr 2:58,038,483...58,137,622
JBrowse link
G CNOT7 CCR4-NOT transcription complex subunit 7 ISO (MGI:MGI:5486537|PMID:19716330)
(PMID:21278420)
UniProtKB PMID:19716330, PMID:21278420 MGI:MGI:5486537 NCBI chr16:40,554,214...40,571,841
Ensembl chr16:40,555,565...40,571,720
JBrowse link
G CPEB3 cytoplasmic polyadenylation element binding protein 3 ISO (PMID:21336257) UniProtKB PMID:21336257 NCBI chr28:6,523,894...6,724,010
Ensembl chr28:6,529,212...6,723,454
JBrowse link
G DHX36 DEAH-box helicase 36 IEA Ensembl GO_REF:0000107 NCBI chr23:48,404,351...48,456,360
Ensembl chr23:48,407,316...48,456,654
JBrowse link
G NANOS1 nanos C2HC-type zinc finger 1 ISO (PMID:24736845) BHF-UCL PMID:24736845 NCBI chr28:29,285,422...29,287,236 JBrowse link
G NANOS2 nanos C2HC-type zinc finger 2 IEA Ensembl GO_REF:0000107 NCBI chr 1:109,716,634...109,717,701
Ensembl chr 1:109,716,699...109,717,115
JBrowse link
G NANOS3 nanos C2HC-type zinc finger 3 IEA Ensembl GO_REF:0000107 Ensembl chr20:48,591,081...48,591,755 JBrowse link
G PABPC1 poly(A) binding protein cytoplasmic 1 ISO (MGI:MGI:5486537|PMID:19716330) UniProtKB PMID:19716330 MGI:MGI:5486537 NCBI chr13:2,563,698...2,580,610
Ensembl chr13:2,564,065...2,580,368
JBrowse link
G TNRC6B trinucleotide repeat containing adaptor 6B ISO (PMID:19716330) UniProtKB PMID:19716330 NCBI chr10:24,852,168...25,094,400
Ensembl chr10:24,813,854...25,094,393
JBrowse link
G TNRC6C trinucleotide repeat containing adaptor 6C ISO (PMID:21984185) UniProtKB PMID:21984185 NCBI chr 9:3,018,599...3,122,664
Ensembl chr 9:3,020,533...3,171,471
JBrowse link
G TOB1 transducer of ERBB2, 1 ISO (PMID:21336257) UniProtKB PMID:21336257 NCBI chr 9:26,736,805...26,741,119
Ensembl chr 9:26,736,675...26,740,177
JBrowse link
G ZFP36 ZFP36 ring finger protein ISO (PMID:12748283)
(MGI:MGI:5487524|PMID:21278420)
UniProtKB PMID:12748283, PMID:21278420 MGI:MGI:5487524 NCBI chr 1:113,815,972...113,818,093
Ensembl chr 1:113,816,273...113,818,065
JBrowse link
G ZFP36L1 ZFP36 ring finger protein like 1 ISO PMID:12748283 UniProt PMID:12748283 RGD:11344945 NCBI chr 8:42,663,287...42,668,665
Ensembl chr 8:42,664,223...42,668,514
JBrowse link
G ZFP36L2 ZFP36 ring finger protein like 2 IEA Ensembl GO_REF:0000107 NCBI chr10:45,746,952...45,751,268
Ensembl chr10:45,748,936...45,751,250
JBrowse link
positive regulation of nuclear-transcribed mRNA poly(A) tail shortening term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGO2 argonaute RISC catalytic component 2 IEA Ensembl GO_REF:0000107 NCBI chr13:35,169,243...35,230,252
Ensembl chr13:35,180,912...35,268,577
JBrowse link
G BTG2 BTG anti-proliferation factor 2 ISO (PMID:18337750) MGI PMID:18337750 NCBI chr38:70,921...75,149
Ensembl chr38:70,452...72,976
JBrowse link
G CNOT1 CCR4-NOT transcription complex subunit 1 IEA Ensembl GO_REF:0000107 NCBI chr 2:58,038,456...58,138,364
Ensembl chr 2:58,038,483...58,137,622
JBrowse link
G CNOT7 CCR4-NOT transcription complex subunit 7 IEA Ensembl GO_REF:0000107 NCBI chr16:40,554,214...40,571,841
Ensembl chr16:40,555,565...40,571,720
JBrowse link
G CPEB3 cytoplasmic polyadenylation element binding protein 3 IEA Ensembl GO_REF:0000107 NCBI chr28:6,523,894...6,724,010
Ensembl chr28:6,529,212...6,723,454
JBrowse link
G EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1 ISO (PMID:32354837) UniProt PMID:32354837 NCBI chr26:24,355,326...24,403,306
Ensembl chr26:24,355,826...24,402,827
JBrowse link
G PABPC1 poly(A) binding protein cytoplasmic 1 IEA Ensembl GO_REF:0000107 NCBI chr13:2,563,698...2,580,610
Ensembl chr13:2,564,065...2,580,368
JBrowse link
G POLR2G RNA polymerase II subunit G IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr18:53,916,431...53,919,724
Ensembl chr18:53,916,435...53,919,549
JBrowse link
G TNRC6A trinucleotide repeat containing adaptor 6A IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:21,247,492...21,454,424
Ensembl chr 6:21,248,948...21,420,719
JBrowse link
G TNRC6B trinucleotide repeat containing adaptor 6B IBA
IEA
(PMID:21873635) GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr10:24,852,168...25,094,400
Ensembl chr10:24,813,854...25,094,393
JBrowse link
G TNRC6C trinucleotide repeat containing adaptor 6C IBA
IEA
(PMID:21873635) GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr 9:3,018,599...3,122,664
Ensembl chr 9:3,020,533...3,171,471
JBrowse link
G TOB1 transducer of ERBB2, 1 IEA Ensembl GO_REF:0000107 NCBI chr 9:26,736,805...26,741,119
Ensembl chr 9:26,736,675...26,740,177
JBrowse link
G ZFP36 ZFP36 ring finger protein IEA Ensembl GO_REF:0000107 NCBI chr 1:113,815,972...113,818,093
Ensembl chr 1:113,816,273...113,818,065
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16162
    metabolic process 10637
      catabolic process 2240
        positive regulation of catabolic process 460
          positive regulation of cellular catabolic process 390
            positive regulation of mRNA catabolic process 52
              positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 19
                positive regulation of exonucleolytic catabolism of deadenylated mRNA 0
                positive regulation of nuclear-transcribed mRNA poly(A) tail shortening 13
Path 2
Term Annotations click to browse term
  biological_process 16162
    metabolic process 10637
      cellular metabolic process 9630
        cellular aromatic compound metabolic process 5109
          nucleobase-containing compound metabolic process 4907
            nucleic acid metabolic process 4459
              RNA metabolic process 4001
                RNA catabolic process 256
                  mRNA catabolic process 223
                    nuclear-transcribed mRNA catabolic process 113
                      nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 52
                        regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 21
                          positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 19
                            positive regulation of exonucleolytic catabolism of deadenylated mRNA 0
                            positive regulation of nuclear-transcribed mRNA poly(A) tail shortening 13
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.