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ONTOLOGY REPORT - ANNOTATIONS


Term:extracellular negative regulation of signal transduction
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Accession:GO:1900116 term browser browse the term
Definition:Any negative regulation of signal transduction that takes place in extracellular region.
Synonyms:exact_synonym: down regulation of signal transduction in extracellular region;   downregulation of signal transduction in extracellular region;   negative regulation of signaling pathway in extracellular region;   negative regulation of signalling pathway in extracellular region
 narrow_synonym: extracellular inhibition of signaling pathway;   inhibition of signal transduction in extracellular region


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extracellular negative regulation of signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zfp653 zinc finger protein 653 involved_in ISS
ISO
(MGI:2679396|PMID:12920234) UniProt
MGI
PMID:12920234 GO_REF:0000096 MGI:2679396 MGI:4834177 NCBI chr 9:22,055,411...22,071,395
Ensembl chr 9:22,055,411...22,071,376
JBrowse link
sequestering of BMP from receptor via BMP binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grem1 gremlin 1, DAN family BMP antagonist involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 2:113,748,675...113,758,648
Ensembl chr 2:113,746,164...113,758,646
JBrowse link
G Grem2 gremlin 2, DAN family BMP antagonist involved_in IBA
IMP
(MGI:6201960|PMID:21873635)
(MGI:5507937|PMID:23063586)
GO_Central
UniProt
PMID:21873635 PMID:23063586 MGI:5507937 MGI:6201960 NCBI chr 1:174,833,785...174,921,911
Ensembl chr 1:174,833,785...174,921,819
JBrowse link
G Nbl1 NBL1, DAN family BMP antagonist involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 4:139,082,291...139,093,126
Ensembl chr 4:139,082,284...139,092,993
JBrowse link
sequestering of BMP in extracellular matrix term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cer1 cerberus 1, DAN family BMP antagonist involved_in IDA
ISO
IBA
(MGI:1858315|PMID:10748465)
(MGI:6201960|PMID:21873635)
BHF-UCL
MGI
GO_Central
PMID:10748465 PMID:21873635 GO_REF:0000096 MGI:1858315 MGI:4834177 MGI:6201960 NCBI chr 4:82,881,751...82,885,151
Ensembl chr 4:82,881,751...82,885,148
JBrowse link
G Dand5 DAN domain family member 5, BMP antagonist involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 8:84,815,405...84,832,265
Ensembl chr 8:84,815,404...84,832,409
JBrowse link
G Fbn1 fibrillin 1 involved_in IMP (MGI:4836762|PMID:20855508) BHF-UCL PMID:20855508 MGI:4836762 NCBI chr 2:125,300,594...125,506,485
Ensembl chr 2:125,300,594...125,507,993
JBrowse link
G Nbl1 NBL1, DAN family BMP antagonist involved_in IDA (MGI:1203284|PMID:9660951) BHF-UCL PMID:9660951 MGI:1203284 NCBI chr 4:139,082,291...139,093,126
Ensembl chr 4:139,082,284...139,092,993
JBrowse link
sequestering of extracellular ligand from receptor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd46 CD46 antigen, complement regulatory protein involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 1:195,038,971...195,098,784
Ensembl chr 1:195,036,826...195,092,249
JBrowse link
sequestering of nodal from receptor via nodal binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dand5 DAN domain family member 5, BMP antagonist involved_in IDA (MGI:3055649|PMID:15466485) BHF-UCL PMID:15466485 MGI:3055649 NCBI chr 8:84,815,405...84,832,265
Ensembl chr 8:84,815,404...84,832,409
JBrowse link
sequestering of TGFbeta in extracellular matrix term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbn1 fibrillin 1 involved_in IMP (MGI:4836762|PMID:20855508) BHF-UCL PMID:20855508 MGI:4836762 NCBI chr 2:125,300,594...125,506,485
Ensembl chr 2:125,300,594...125,507,993
JBrowse link
G Fbn2 fibrillin 2 involved_in IMP (MGI:4836762|PMID:20855508) BHF-UCL PMID:20855508 MGI:4836762 NCBI chr18:58,008,623...58,210,572
Ensembl chr18:58,008,623...58,210,487
JBrowse link
G Ltbp1 latent transforming growth factor beta binding protein 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr17:75,005,480...75,392,512
Ensembl chr17:75,005,568...75,392,512
JBrowse link
G Nrros negative regulator of reactive oxygen species involved_in IDA (MGI:6192878|PMID:29909984) UniProt PMID:29909984 MGI:6192878 NCBI chr16:32,142,785...32,165,594
Ensembl chr16:32,142,785...32,165,594
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28616
    cellular process 17619
      signal transduction 6515
        negative regulation of signal transduction 1288
          extracellular negative regulation of signal transduction 11
            sequestering of extracellular ligand from receptor + 10
Path 2
Term Annotations click to browse term
  biological_process 28616
    biological regulation 13270
      regulation of biological process 12618
        regulation of cellular process 12052
          signal transduction 6515
            regulation of signal transduction 2996
              extracellular regulation of signal transduction 11
                extracellular negative regulation of signal transduction 11
                  sequestering of extracellular ligand from receptor + 10
paths to the root