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ONTOLOGY REPORT - ANNOTATIONS

Term:extracellular negative regulation of signal transduction
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Accession:GO:1900116 term browser browse the term
Definition:Any negative regulation of signal transduction that takes place in extracellular region.
Synonyms:exact_synonym: down regulation of signal transduction in extracellular region;   downregulation of signal transduction in extracellular region;   negative regulation of signaling pathway in extracellular region;   negative regulation of signalling pathway in extracellular region
 narrow_synonym: extracellular inhibition of signaling pathway;   inhibition of signal transduction in extracellular region


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extracellular negative regulation of signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ZNF653 zinc finger protein 653 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:49,867,522...49,883,889
Ensembl chr20:49,866,056...49,883,847 		JBrowse link
sequestering of BMP from receptor via BMP binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GREM1 gremlin 1, DAN family BMP antagonist involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr30:2,219,535...2,231,868
Ensembl chr30:2,222,898...2,225,418 		JBrowse link
G GREM2 gremlin 2, DAN family BMP antagonist involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:32,048,151...32,157,698
Ensembl chr 7:32,048,183...32,157,146 		JBrowse link
G NBL1 NBL1, DAN family BMP antagonist involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 2:79,040,206...79,102,792
Ensembl chr 2:79,041,105...79,102,820 		JBrowse link
sequestering of BMP in extracellular matrix term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CER1 cerberus 1, DAN family BMP antagonist involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:35,155,568...35,159,085
Ensembl chr11:35,156,430...35,158,942 		JBrowse link
G FBN1 fibrillin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:14,640,973...14,864,151
Ensembl chr30:14,640,973...14,864,151 		JBrowse link
G NBL1 NBL1, DAN family BMP antagonist involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:79,040,206...79,102,792
Ensembl chr 2:79,041,105...79,102,820 		JBrowse link
sequestering of extracellular ligand from receptor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC609365 CD46 molecule, complement regulatory protein-like involved_in ISO (PMID:23086448) UniProt PMID:23086448 NCBI chr 7:6,602,762...6,646,561 JBrowse link
sequestering of nodal from receptor via nodal binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DAND5 DAN domain BMP antagonist family member 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:49,225,351...49,228,940
Ensembl chr20:49,225,990...49,228,940 		JBrowse link
sequestering of TGFbeta in extracellular matrix term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FBN1 fibrillin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:14,640,973...14,864,151
Ensembl chr30:14,640,973...14,864,151 		JBrowse link
G FBN2 fibrillin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:17,311,238...17,551,536
Ensembl chr11:17,311,226...17,551,536 		JBrowse link
G LTBP1 latent transforming growth factor beta binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:26,129,528...26,521,782
Ensembl chr17:26,130,781...26,521,779 		JBrowse link
G NRROS negative regulator of reactive oxygen species involved_in IEA Ensembl GO_REF:0000107 NCBI chr33:29,682,182...29,699,469
Ensembl chr33:29,692,371...29,767,771 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17878
    cellular process 16920
      signal transduction 6300
        negative regulation of signal transduction 1443
          extracellular negative regulation of signal transduction 11
            sequestering of extracellular ligand from receptor + 10
Path 2
Term Annotations click to browse term
  biological_process 17878
    biological regulation 12365
      regulation of biological process 12008
        signaling 6853
          signal transduction 6300
            regulation of signal transduction 3157
              extracellular regulation of signal transduction 11
                extracellular negative regulation of signal transduction 11
                  sequestering of extracellular ligand from receptor + 10
paths to the root