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ONTOLOGY REPORT - ANNOTATIONS


Term:extracellular negative regulation of signal transduction
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Accession:GO:1900116 term browser browse the term
Definition:Any negative regulation of signal transduction that takes place in extracellular region.
Synonyms:exact_synonym: down regulation of signal transduction in extracellular region;   downregulation of signal transduction in extracellular region;   negative regulation of signaling pathway in extracellular region;   negative regulation of signalling pathway in extracellular region
 narrow_synonym: extracellular inhibition of signaling pathway;   inhibition of signal transduction in extracellular region



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extracellular negative regulation of signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zfp653 zinc finger protein 653 involved_in ISO (PMID:12920234) RGD PMID:12920234 NCBI chr 8:20,586,563...20,605,439
Ensembl chr 8:20,586,563...20,604,864
JBrowse link
sequestering of BMP from receptor via BMP binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grem1 gremlin 1, DAN family BMP antagonist involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:100,512,317...100,524,001
Ensembl chr 3:100,512,313...100,524,082
JBrowse link
G Grem2 gremlin 2, DAN family BMP antagonist involved_in IBA
ISO
PMID:21873635
(MGI:5507937|PMID:23063586)
RGD PMID:23063586 PMID:21873635 MGI:5507937, RGD:13792537 NCBI chr13:86,778,543...86,871,509
Ensembl chr13:86,778,500...86,871,615
JBrowse link
G Nbl1 NBL1, DAN family BMP antagonist involved_in ISO
IBA
(PMID:23063586)
PMID:21873635
RGD PMID:23063586 PMID:21873635 RGD:13792537 NCBI chr 5:151,318,752...151,329,948
Ensembl chr 5:151,318,754...151,338,719
JBrowse link
sequestering of BMP in extracellular matrix term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cer1 cerberus 1, DAN family BMP antagonist involved_in ISO
IBA
(PMID:9660951)
(MGI:1858315|PMID:10748465)
PMID:21873635
RGD PMID:9660951 PMID:10748465 PMID:21873635 MGI:1858315, RGD:13792537 NCBI chr 5:97,306,427...97,309,783
Ensembl chr 5:97,306,431...97,309,783
JBrowse link
G Dand5 DAN domain BMP antagonist family member 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr19:23,330,917...23,340,486
Ensembl chr19:23,334,164...23,339,589
JBrowse link
G Fbn1 fibrillin 1 involved_in ISO (MGI:4836762|PMID:20855508) RGD PMID:20855508 MGI:4836762 NCBI chr 3:112,554,257...112,750,835
Ensembl chr 3:112,554,925...112,750,889
JBrowse link
G Nbl1 NBL1, DAN family BMP antagonist involved_in ISO (MGI:1203284|PMID:9660951) RGD PMID:9660951 MGI:1203284 NCBI chr 5:151,318,752...151,329,948
Ensembl chr 5:151,318,754...151,338,719
JBrowse link
sequestering of extracellular ligand from receptor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd46 CD46 molecule involved_in ISO (PMID:23086448) RGD PMID:23086448 NCBI chr13:106,575,586...106,606,325
Ensembl chr13:106,574,858...106,660,445
JBrowse link
sequestering of nodal from receptor via nodal binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dand5 DAN domain BMP antagonist family member 5 involved_in ISO (MGI:3055649|PMID:15466485) RGD PMID:15466485 MGI:3055649 NCBI chr19:23,330,917...23,340,486
Ensembl chr19:23,334,164...23,339,589
JBrowse link
sequestering of TGFbeta in extracellular matrix term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbn1 fibrillin 1 involved_in ISO (MGI:4836762|PMID:20855508) RGD PMID:20855508 MGI:4836762 NCBI chr 3:112,554,257...112,750,835
Ensembl chr 3:112,554,925...112,750,889
JBrowse link
G Fbn2 fibrillin 2 involved_in ISO (MGI:4836762|PMID:20855508) RGD PMID:20855508 MGI:4836762 NCBI chr18:51,499,737...51,703,976
Ensembl chr18:51,499,737...51,703,976
JBrowse link
G Ltbp1 latent transforming growth factor beta binding protein 1 involved_in ISO
ISS
(PMID:2022183), (PMID:8617200)
GO_REF:0000024
RGD
UniProt
PMID:2022183 PMID:8617200 GO_REF:0000024 NCBI chr 6:20,029,629...20,425,339
Ensembl chr 6:20,029,629...20,425,349
JBrowse link
G Nrros negative regulator of reactive oxygen species involved_in ISS
ISO
GO_REF:0000024
(MGI:6192878|PMID:29909984)
UniProt
RGD
PMID:29909984 GO_REF:0000024 MGI:6192878 NCBI chr11:68,628,641...68,646,152
Ensembl chr11:68,628,712...68,646,142
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20050
    cellular process 18632
      signal transduction 7126
        negative regulation of signal transduction 1363
          extracellular negative regulation of signal transduction 11
            sequestering of extracellular ligand from receptor + 10
Path 2
Term Annotations click to browse term
  biological_process 20050
    biological regulation 13942
      regulation of biological process 13176
        regulation of cellular process 12448
          signal transduction 7126
            regulation of signal transduction 3126
              extracellular regulation of signal transduction 11
                extracellular negative regulation of signal transduction 11
                  sequestering of extracellular ligand from receptor + 10
paths to the root