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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of endoplasmic reticulum unfolded protein response
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Accession:GO:1900102 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of endoplasmic reticulum unfolded protein response.
Synonyms:exact_synonym: down regulation of ER unfolded protein response;   down regulation of endoplasmic reticulum unfolded protein response;   down regulation of erUPR;   downregulation of ER unfolded protein response;   downregulation of endoplasmic reticulum unfolded protein response;   downregulation of erUPR;   inhibition of ER unfolded protein response;   inhibition of erUPR;   negative regulation of ER unfolded protein response;   negative regulation of erUPR
 narrow_synonym: inhibition of endoplasmic reticulum unfolded protein response
 related_synonym: down regulation of SREBP-mediated signalling pathway;   downregulation of SREBP-mediated signalling pathway;   inhibition of SREBP-mediated signalling pathway;   negative regulation of SREBP-mediated signalling pathway

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negative regulation of endoplasmic reticulum unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crebrf CREB3 regulatory factor involved_in ISO (PMID:18391022) UniProt PMID:18391022 NCBI chrNW_004955408:25,718,523...25,769,551
Ensembl chrNW_004955408:25,719,187...25,774,555 		JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISO (PMID:25239945) UniProt PMID:25239945 NCBI chrNW_004955455:3,037,885...3,041,827 JBrowse link
negative regulation of ATF6-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf6b activating transcription factor 6 beta involved_in ISO (PMID:9837962) UniProt PMID:9837962 NCBI chrNW_004955437:582,083...592,026
Ensembl chrNW_004955437:582,431...591,810 		JBrowse link
G Wfs1 wolframin ER transmembrane glycoprotein involved_in ISO (PMID:20160352) ParkinsonsUK-UCL PMID:20160352 RGD:10047363 NCBI chrNW_004955514:3,902,508...3,924,281
Ensembl chrNW_004955514:3,902,454...3,924,610 		JBrowse link
negative regulation of IRE1-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bfar bifunctional apoptosis regulator involved_in ISO (PMID:21068390) ParkinsonsUK-UCL PMID:21068390 NCBI chrNW_004955442:4,229,236...4,255,623
Ensembl chrNW_004955442:4,226,756...4,255,623 		JBrowse link
G Ddrgk1 DDRGK domain containing 1 involved_in ISO (PMID:28128204), (PMID:32160526)
(MGI:5912977|PMID:28128204)		 UniProt PMID:28128204 PMID:32160526 MGI:5912977 NCBI chrNW_004955415:14,085,404...14,098,220
Ensembl chrNW_004955415:14,085,404...14,098,856 		JBrowse link
G Pdia6 protein disulfide isomerase family A member 6 involved_in ISO (PMID:24508390) WB PMID:24508390 NCBI chrNW_004955487:5,735,698...5,744,601
Ensembl chrNW_004955487:5,735,698...5,748,015 		JBrowse link
G Ufl1 UFM1 specific ligase 1 involved_in ISO (PMID:32160526) UniProt PMID:32160526 NCBI chrNW_004955411:22,548,139...22,577,287
Ensembl chrNW_004955411:22,548,219...22,580,903 		JBrowse link
negative regulation of PERK-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca7 ATP binding cassette subfamily A member 7 involved_in ISO (MGI:5774886|PMID:27030769) ARUK-UCL PMID:27030769 MGI:5774886 NCBI chrNW_004955495:6,818,002...6,838,177
Ensembl chrNW_004955495:6,815,562...6,836,772 		JBrowse link
G Nck1 NCK adaptor protein 1 involved_in ISO (PMID:14676213)
(MGI:5613478|PMID:14676213)		 ParkinsonsUK-UCL PMID:14676213 MGI:5613478 NCBI chrNW_004955501:1,867,956...1,963,091 JBrowse link
G Nck2 NCK adaptor protein 2 involved_in ISO (MGI:5613478|PMID:14676213) ParkinsonsUK-UCL PMID:14676213 MGI:5613478 NCBI chrNW_004955470:10,487,962...10,593,046
Ensembl chrNW_004955470:10,487,481...10,593,046 		JBrowse link
G Ptpn1 protein tyrosine phosphatase non-receptor type 1 involved_in ISO (PMID:21216966)
(MGI:5619464|PMID:21216966)		 ParkinsonsUK-UCL PMID:21216966 MGI:5619464 NCBI chrNW_004955445:7,754,313...7,819,229
Ensembl chrNW_004955445:7,754,319...7,819,275 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12346
    cellular process 11480
      signal transduction 3950
        negative regulation of signal transduction 1223
          negative regulation of endoplasmic reticulum unfolded protein response 12
            negative regulation of ATF6-mediated unfolded protein response 2
            negative regulation of IRE1-mediated unfolded protein response 4
            negative regulation of PERK-mediated unfolded protein response 4
Path 2
Term Annotations click to browse term
  biological_process 12346
    response to stimulus 6681
      cellular response to stimulus 5381
        cellular response to chemical stimulus 2540
          cellular response to organic substance 1942
            cellular response to topologically incorrect protein 84
              cellular response to unfolded protein 70
                endoplasmic reticulum unfolded protein response 59
                  regulation of endoplasmic reticulum unfolded protein response 23
                    negative regulation of endoplasmic reticulum unfolded protein response 12
                      negative regulation of ATF6-mediated unfolded protein response 2
                      negative regulation of IRE1-mediated unfolded protein response 4
                      negative regulation of PERK-mediated unfolded protein response 4
paths to the root