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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of endoplasmic reticulum unfolded protein response
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Accession:GO:1900101 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of endoplasmic reticulum unfolded protein response.
Synonyms:exact_synonym: regulation of ER unfolded protein response;   regulation of erUPR
 related_synonym: regulation of SREBP-mediated signalling pathway


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regulation of endoplasmic reticulum unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PIGBOS1 PIGB opposite strand 1 involved_in ISO (PMID:31653868) UniProt PMID:31653868 NCBI chr 1:116,519,834...116,522,515 JBrowse link
negative regulation of ATF6-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATF6B activating transcription factor 6 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:24,153,551...24,171,743
Ensembl chr 7:24,153,572...24,171,840
JBrowse link
G WFS1 wolframin ER transmembrane glycoprotein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:4,362,678...4,405,185
Ensembl chr 8:4,362,678...4,385,272
JBrowse link
negative regulation of endoplasmic reticulum unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CREBRF CREB3 regulatory factor involved_in ISO (PMID:18391022) UniProt PMID:18391022 NCBI chr16:51,146,015...51,210,806
Ensembl chr16:51,150,560...51,260,685
JBrowse link
G XBP1 X-box binding protein 1 involved_in ISO (PMID:25239945) UniProt PMID:25239945 NCBI chr14:46,011,239...46,016,526
Ensembl chr14:46,008,377...46,017,036
JBrowse link
negative regulation of IRE1-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BFAR bifunctional apoptosis regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:28,572,789...28,612,659
Ensembl chr 3:28,573,393...28,612,218
JBrowse link
G DDRGK1 DDRGK domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:32,479,981...32,491,401
Ensembl chr17:32,479,976...32,491,400
JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 involved_in ISS UniProt GO_REF:0000024 NCBI chr 1:265,930,044...265,934,959
Ensembl chr 1:265,930,045...265,934,904
JBrowse link
G PDIA6 protein disulfide isomerase family A member 6 involved_in ISO (MGI:5571560|PMID:24508390) WB PMID:24508390 MGI:5571560 NCBI chr 3:125,752,079...125,774,225
Ensembl chr 3:125,751,970...125,776,955
JBrowse link
G UFL1 UFM1 specific ligase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:63,638,589...63,698,931
Ensembl chr 1:63,638,592...63,700,481
JBrowse link
negative regulation of PERK-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA7 ATP binding cassette subfamily A member 7 involved_in ISO (MGI:5774886|PMID:27030769) ARUK-UCL PMID:27030769 MGI:5774886 NCBI chr 2:77,357,161...77,375,349
Ensembl chr 2:77,357,211...77,375,180
JBrowse link
G NCK1 NCK adaptor protein 1 involved_in IEA
IBA
(PMID:21873635) Ensembl
GO_Central
PMID:21873635 GO_REF:0000107 NCBI chr13:77,863,655...77,940,944
Ensembl chr13:77,863,701...77,986,156
JBrowse link
G NCK2 NCK adaptor protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:49,063,813...49,222,274
Ensembl chr 3:49,063,988...49,198,664
JBrowse link
G PTPN1 protein tyrosine phosphatase non-receptor type 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:52,017,100...52,086,747
Ensembl chr17:52,017,104...52,086,736
JBrowse link
positive regulation of ATF6-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATF6 activating transcription factor 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:88,591,279...88,806,156
Ensembl chr 4:88,591,280...88,818,372
JBrowse link
positive regulation of endoplasmic reticulum unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAK1 BCL2 antagonist/killer 1 involved_in ISO (PMID:16645094) UniProt PMID:16645094 NCBI chr 7:29,808,849...29,815,345 JBrowse link
G BAX BCL2 associated X, apoptosis regulator involved_in ISO (PMID:16645094) UniProt PMID:16645094 NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,187,260...54,228,144
JBrowse link
G ERN1 endoplasmic reticulum to nucleus signaling 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:14,881,913...14,963,290
Ensembl chr12:14,881,923...14,997,426
JBrowse link
G ICAM2 intercellular adhesion molecule 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:14,986,636...14,991,639
Ensembl chr12:14,881,923...14,997,426
JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:46,434,757...46,523,626
Ensembl chr16:46,434,873...46,523,609
JBrowse link
G XBP1 X-box binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:46,011,239...46,016,526
Ensembl chr14:46,008,377...46,017,036
JBrowse link
positive regulation of IRE1-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGR2 anterior gradient 2, protein disulphide isomerase family member involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:86,042,070...86,053,893
Ensembl chr 9:86,039,015...86,053,857
JBrowse link
G TMEM33 transmembrane protein 33 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:33,012,540...33,036,448
Ensembl chr 8:33,012,333...33,036,438
JBrowse link
positive regulation of PERK-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGR2 anterior gradient 2, protein disulphide isomerase family member involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:86,042,070...86,053,893
Ensembl chr 9:86,039,015...86,053,857
JBrowse link
G BOK BCL2 family apoptosis regulator BOK involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:140,171,134...140,184,126
Ensembl chr15:140,171,143...140,184,124
JBrowse link
G PTPN2 protein tyrosine phosphatase non-receptor type 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:96,769,862...96,847,136
Ensembl chr 6:96,770,251...96,847,133
JBrowse link
G TMEM33 transmembrane protein 33 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:33,012,540...33,036,448
Ensembl chr 8:33,012,333...33,036,438
JBrowse link
regulation of IRE1-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COPS5 COP9 signalosome subunit 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:67,740,528...67,758,153
Ensembl chr 4:67,738,939...67,758,150
JBrowse link
G FICD FIC domain protein adenylyltransferase involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:42,261,505...42,269,184
Ensembl chr14:42,260,069...42,266,858
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16567
    regulation of biological process 11452
      regulation of response to stimulus 3701
        regulation of signal transduction 2839
          regulation of endoplasmic reticulum unfolded protein response 26
            negative regulation of endoplasmic reticulum unfolded protein response + 13
            positive regulation of endoplasmic reticulum unfolded protein response + 11
            regulation of ATF6-mediated unfolded protein response + 3
            regulation of IRE1-mediated unfolded protein response + 9
            regulation of PERK-mediated unfolded protein response + 8
Path 2
Term Annotations click to browse term
  biological_process 16567
    response to stimulus 9043
      cellular response to stimulus 7690
        cellular response to chemical stimulus 3285
          cellular response to organic substance 2691
            cellular response to topologically incorrect protein 108
              cellular response to unfolded protein 89
                endoplasmic reticulum unfolded protein response 71
                  regulation of endoplasmic reticulum unfolded protein response 26
                    negative regulation of endoplasmic reticulum unfolded protein response + 13
                    positive regulation of endoplasmic reticulum unfolded protein response + 11
                    regulation of ATF6-mediated unfolded protein response + 3
                    regulation of IRE1-mediated unfolded protein response + 9
                    regulation of PERK-mediated unfolded protein response + 8
paths to the root