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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of endoplasmic reticulum unfolded protein response
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Accession:GO:1900101 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of endoplasmic reticulum unfolded protein response.
Synonyms:exact_synonym: regulation of ER unfolded protein response;   regulation of erUPR
 related_synonym: regulation of SREBP-mediated signalling pathway


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regulation of endoplasmic reticulum unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pigbos1 Pigb opposite strand 1 involved_in ISO (PMID:31653868) UniProt PMID:31653868 NCBI chr 9:73,039,718...73,042,782
Ensembl chr 9:73,039,718...73,042,779
JBrowse link
negative regulation of ATF6-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf6b activating transcription factor 6 beta involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr17:34,647,146...34,655,074
Ensembl chr17:34,647,146...34,655,074
JBrowse link
G Wfs1 wolframin ER transmembrane glycoprotein involved_in ISO MGI GO_REF:0000096 MGI:4417868 MGI:4834177 NCBI chr 5:36,966,104...36,988,982
Ensembl chr 5:36,966,104...36,989,205
JBrowse link
negative regulation of endoplasmic reticulum unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crebrf CREB3 regulatory factor involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr17:26,715,594...26,776,637
Ensembl chr17:26,715,650...26,776,635
JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr11:5,520,641...5,525,993
Ensembl chr11:5,520,659...5,525,893
JBrowse link
negative regulation of IRE1-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bfar bifunctional apoptosis regulator involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr16:13,671,858...13,703,612
Ensembl chr16:13,671,858...13,703,612
Ensembl chr16:13,671,858...13,703,612
JBrowse link
G Ddrgk1 DDRGK domain containing 1 involved_in IMP
ISO
(MGI:5912977|PMID:28128204) UniProt
MGI
PMID:28128204 GO_REF:0000096 MGI:4834177 MGI:5912977 NCBI chr 2:130,654,033...130,664,654
Ensembl chr 2:130,653,960...130,664,659
JBrowse link
G Pdia6 protein disulfide isomerase associated 6 involved_in IMP (MGI:5571560|PMID:24508390) WB PMID:24508390 MGI:5571560 NCBI chr12:17,266,589...17,284,785
Ensembl chr12:17,266,545...17,284,770
JBrowse link
G Ufl1 UFM1 specific ligase 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 4:25,247,149...25,281,821
Ensembl chr 4:25,248,600...25,281,821
JBrowse link
negative regulation of PERK-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca7 ATP-binding cassette, sub-family A (ABC1), member 7 involved_in IMP (MGI:5774886|PMID:27030769) ARUK-UCL PMID:27030769 MGI:5774886 NCBI chr10:79,996,453...80,015,572
Ensembl chr10:79,996,494...80,015,572
JBrowse link
G Nck1 non-catalytic region of tyrosine kinase adaptor protein 1 involved_in ISO
IBA
IGI
(MGI:6201960|PMID:21873635)
(MGI:5613478|PMID:14676213)
MGI
GO_Central
ParkinsonsUK-UCL
PMID:14676213 PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:5613478 MGI:6201960 NCBI chr 9:100,494,302...100,546,134
Ensembl chr 9:100,492,293...100,546,134
JBrowse link
G Nck2 non-catalytic region of tyrosine kinase adaptor protein 2 involved_in IGI
IBA
(MGI:5613478|PMID:14676213)
(MGI:6201960|PMID:21873635)
ParkinsonsUK-UCL
GO_Central
PMID:14676213 PMID:21873635 MGI:5613478 MGI:6201960 NCBI chr 1:43,445,483...43,570,518
Ensembl chr 1:43,444,579...43,570,515
JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 involved_in IMP
ISO
(MGI:5619464|PMID:21216966) ParkinsonsUK-UCL
MGI
PMID:21216966 GO_REF:0000096 MGI:4834177 MGI:5619464 NCBI chr 2:167,930,750...167,979,385
Ensembl chr 2:167,932,057...167,979,385
JBrowse link
positive regulation of ATF6-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf6 activating transcription factor 6 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 1:170,704,457...170,868,585
Ensembl chr 1:170,704,674...170,867,771
JBrowse link
positive regulation of endoplasmic reticulum unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bak1 BCL2-antagonist/killer 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr17:27,019,812...27,028,627
Ensembl chr17:27,019,810...27,029,009
JBrowse link
G Bax BCL2-associated X protein involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 7:45,461,695...45,466,903
Ensembl chr 7:45,461,697...45,466,898
JBrowse link
G Ern1 endoplasmic reticulum (ER) to nucleus signalling 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr11:106,397,620...106,487,796
Ensembl chr11:106,394,650...106,487,852
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr13:101,680,761...101,768,217
Ensembl chr13:101,680,563...101,768,217
JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr11:5,520,641...5,525,993
Ensembl chr11:5,520,659...5,525,893
JBrowse link
positive regulation of IRE1-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agr2 anterior gradient 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr12:35,992,925...36,004,081
Ensembl chr12:35,992,907...36,004,087
JBrowse link
G Tmem33 transmembrane protein 33 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 5:67,260,565...67,291,461
Ensembl chr 5:67,260,565...67,291,461
JBrowse link
positive regulation of PERK-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agr2 anterior gradient 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr12:35,992,925...36,004,081
Ensembl chr12:35,992,907...36,004,087
JBrowse link
G Bok BCL2-related ovarian killer involved_in IMP (MGI:5648772|PMID:26015568) UniProt PMID:26015568 MGI:5648772 NCBI chr 1:93,685,575...93,695,770
Ensembl chr 1:93,685,660...93,695,764
JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in IMP (MGI:5619464|PMID:21216966) ParkinsonsUK-UCL PMID:21216966 MGI:5619464 NCBI chr18:67,665,501...67,724,632
Ensembl chr18:67,665,511...67,724,595
JBrowse link
G Tmem33 transmembrane protein 33 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 5:67,260,565...67,291,461
Ensembl chr 5:67,260,565...67,291,461
JBrowse link
regulation of IRE1-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cops5 COP9 signalosome subunit 5 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 1:10,024,600...10,038,159
Ensembl chr 1:10,024,601...10,038,168
JBrowse link
G Ficd FIC domain containing involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 5:113,735,758...113,740,607
Ensembl chr 5:113,735,803...113,740,600
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28607
    regulation of biological process 12586
      regulation of response to stimulus 4064
        regulation of signal transduction 2969
          regulation of endoplasmic reticulum unfolded protein response 24
            negative regulation of endoplasmic reticulum unfolded protein response + 12
            positive regulation of endoplasmic reticulum unfolded protein response + 10
            regulation of ATF6-mediated unfolded protein response + 3
            regulation of IRE1-mediated unfolded protein response + 8
            regulation of PERK-mediated unfolded protein response + 8
Path 2
Term Annotations click to browse term
  biological_process 28607
    response to stimulus 10431
      cellular response to stimulus 8540
        cellular response to chemical stimulus 3686
          cellular response to organic substance 3011
            cellular response to topologically incorrect protein 111
              cellular response to unfolded protein 91
                endoplasmic reticulum unfolded protein response 70
                  regulation of endoplasmic reticulum unfolded protein response 24
                    negative regulation of endoplasmic reticulum unfolded protein response + 12
                    positive regulation of endoplasmic reticulum unfolded protein response + 10
                    regulation of ATF6-mediated unfolded protein response + 3
                    regulation of IRE1-mediated unfolded protein response + 8
                    regulation of PERK-mediated unfolded protein response + 8
paths to the root