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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of endoplasmic reticulum unfolded protein response
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Accession:GO:1900101 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of endoplasmic reticulum unfolded protein response.
Synonyms:exact_synonym: regulation of ER unfolded protein response;   regulation of erUPR
 related_synonym: regulation of SREBP-mediated signalling pathway


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regulation of endoplasmic reticulum unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PIGBOS1 PIGB opposite strand 1 involved_in IMP (PMID:31653868) UniProt PMID:31653868 NCBI chr15:55,317,184...55,348,725
Ensembl chr15:55,317,184...55,319,161
JBrowse link
negative regulation of ATF6-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATF6B activating transcription factor 6 beta involved_in IDA (PMID:9837962) UniProt PMID:9837962 NCBI chr 6:32,115,264...32,128,246
Ensembl chr 6:32,115,264...32,128,253
JBrowse link
G WFS1 wolframin ER transmembrane glycoprotein involved_in IDA (PMID:20160352) ParkinsonsUK-UCL PMID:20160352 NCBI chr 4:6,260,368...6,303,265
Ensembl chr 4:6,269,849...6,303,265
JBrowse link
negative regulation of endoplasmic reticulum unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CREBRF CREB3 regulatory factor involved_in IDA (PMID:18391022) UniProt PMID:18391022 NCBI chr 5:173,056,349...173,139,284
Ensembl chr 5:173,056,352...173,139,284
JBrowse link
G RACK1 receptor for activated C kinase 1 involved_in TAS (PMID:22013210) ParkinsonsUK-UCL PMID:22013210 NCBI chr 5:181,236,897...181,243,906
Ensembl chr 5:181,236,897...181,248,096
JBrowse link
G XBP1 X-box binding protein 1 involved_in IDA (PMID:25239945) UniProt PMID:25239945 NCBI chr22:28,794,560...28,800,569
Ensembl chr22:28,794,555...28,800,597
JBrowse link
negative regulation of IRE1-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BFAR bifunctional apoptosis regulator involved_in IMP (PMID:21068390) ParkinsonsUK-UCL PMID:21068390 NCBI chr16:14,632,831...14,669,236
Ensembl chr16:14,632,931...14,669,236
JBrowse link
G DDRGK1 DDRGK domain containing 1 involved_in IDA (PMID:28128204), (PMID:32160526) UniProt PMID:28128204 PMID:32160526 NCBI chr20:3,190,350...3,204,682
Ensembl chr20:3,190,350...3,204,685
JBrowse link
G DNAJB9 DnaJ heat shock protein family (Hsp40) member B9 involved_in ISS UniProt GO_REF:0000024 NCBI chr 7:108,569,874...108,574,850
Ensembl chr 7:108,569,867...108,574,850
JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 involved_in ISS UniProt GO_REF:0000024 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382
JBrowse link
G PDIA6 protein disulfide isomerase family A member 6 involved_in ISO (MGI:5571560|PMID:24508390) WB PMID:24508390 MGI:5571560 NCBI chr 2:10,783,391...10,837,712
Ensembl chr 2:10,783,391...10,837,977
JBrowse link
G UFL1 UFM1 specific ligase 1 involved_in IDA (PMID:32160526) UniProt PMID:32160526 NCBI chr 6:96,521,806...96,555,276
Ensembl chr 6:96,521,595...96,555,276
JBrowse link
negative regulation of PERK-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA7 ATP binding cassette subfamily A member 7 involved_in ISS ARUK-UCL GO_REF:0000024 NCBI chr19:1,040,107...1,065,572
Ensembl chr19:1,039,997...1,065,572
JBrowse link
G NCK1 NCK adaptor protein 1 involved_in IDA
IBA
(PMID:14676213)
(PMID:21873635)
ParkinsonsUK-UCL
GO_Central
PMID:14676213 PMID:21873635 NCBI chr 3:136,862,208...136,951,606
Ensembl chr 3:136,862,208...136,951,606
JBrowse link
G NCK2 NCK adaptor protein 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:105,744,649...105,894,274
Ensembl chr 2:105,744,912...105,894,274
JBrowse link
G PPP1R15A protein phosphatase 1 regulatory subunit 15A involved_in TAS (PMID:22013210) ParkinsonsUK-UCL PMID:22013210 NCBI chr19:48,872,421...48,876,058
Ensembl chr19:48,872,421...48,876,058
JBrowse link
G PPP1R15B protein phosphatase 1 regulatory subunit 15B involved_in TAS (PMID:22013210) ParkinsonsUK-UCL PMID:22013210 NCBI chr 1:204,398,684...204,412,454
Ensembl chr 1:204,403,381...204,411,817
JBrowse link
G PTPN1 protein tyrosine phosphatase non-receptor type 1 involved_in IDA (PMID:21216966) ParkinsonsUK-UCL PMID:21216966 NCBI chr20:50,510,383...50,585,241
Ensembl chr20:50,510,321...50,585,241
JBrowse link
positive regulation of ATF6-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATF6 activating transcription factor 6 involved_in IDA (PMID:9837962) UniProt PMID:9837962 NCBI chr 1:161,766,320...161,964,070
Ensembl chr 1:161,766,298...161,977,574
JBrowse link
positive regulation of endoplasmic reticulum unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAK1 BCL2 antagonist/killer 1 involved_in IMP (PMID:16645094) UniProt PMID:16645094 NCBI chr 6:33,572,552...33,580,296
Ensembl chr 6:33,572,547...33,580,293
JBrowse link
G BAX BCL2 associated X, apoptosis regulator involved_in IMP (PMID:16645094) UniProt PMID:16645094 NCBI chr19:48,954,825...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G ERN1 endoplasmic reticulum to nucleus signaling 1 involved_in IMP (PMID:16645094), (PMID:28128204) UniProt PMID:16645094 PMID:28128204 NCBI chr17:64,039,142...64,132,469
Ensembl chr17:64,039,080...64,130,819
JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 involved_in IMP (PMID:20348923) UniProt PMID:20348923 NCBI chr 5:68,215,737...68,301,821
Ensembl chr 5:68,215,756...68,301,821
JBrowse link
G XBP1 X-box binding protein 1 involved_in IMP (PMID:16645094) UniProt PMID:16645094 NCBI chr22:28,794,560...28,800,569
Ensembl chr22:28,794,555...28,800,597
JBrowse link
positive regulation of IRE1-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGR2 anterior gradient 2, protein disulphide isomerase family member involved_in IDA (PMID:23220234) UniProt PMID:23220234 NCBI chr 7:16,791,811...16,804,999
Ensembl chr 7:16,791,811...16,833,433
JBrowse link
G BAK1 BCL2 antagonist/killer 1 involved_in TAS (PMID:22013210) ParkinsonsUK-UCL PMID:22013210 NCBI chr 6:33,572,552...33,580,296
Ensembl chr 6:33,572,547...33,580,293
JBrowse link
G BAX BCL2 associated X, apoptosis regulator involved_in TAS (PMID:22013210) ParkinsonsUK-UCL PMID:22013210 NCBI chr19:48,954,825...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BBC3 BCL2 binding component 3 involved_in TAS (PMID:22013210) ParkinsonsUK-UCL PMID:22013210 NCBI chr19:47,220,822...47,232,998
Ensembl chr19:47,220,822...47,232,766
JBrowse link
G BCL2L11 BCL2 like 11 involved_in TAS (PMID:22013210) ParkinsonsUK-UCL PMID:22013210 NCBI chr 2:111,120,914...111,168,445
Ensembl chr 2:111,119,378...111,168,445
JBrowse link
G DAB2IP DAB2 interacting protein involved_in TAS (PMID:22013210) ParkinsonsUK-UCL PMID:22013210 NCBI chr 9:121,566,883...121,785,530
Ensembl chr 9:121,567,057...121,785,530
JBrowse link
G PTPN1 protein tyrosine phosphatase non-receptor type 1 involved_in TAS (PMID:22013210) ParkinsonsUK-UCL PMID:22013210 NCBI chr20:50,510,383...50,585,241
Ensembl chr20:50,510,321...50,585,241
JBrowse link
G TMEM33 transmembrane protein 33 involved_in IDA (PMID:26268696) UniProt PMID:26268696 NCBI chr 4:41,935,120...41,960,803
Ensembl chr 4:41,935,129...41,960,803
JBrowse link
positive regulation of PERK-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGR2 anterior gradient 2, protein disulphide isomerase family member involved_in IDA (PMID:23220234) UniProt PMID:23220234 NCBI chr 7:16,791,811...16,804,999
Ensembl chr 7:16,791,811...16,833,433
JBrowse link
G BOK BCL2 family apoptosis regulator BOK involved_in ISS UniProt GO_REF:0000024 NCBI chr 2:241,558,745...241,574,131
Ensembl chr 2:241,551,424...241,574,131
JBrowse link
G PTPN2 protein tyrosine phosphatase non-receptor type 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:12,785,478...12,884,351
Ensembl chr18:12,785,478...12,929,643
JBrowse link
G TMEM33 transmembrane protein 33 involved_in IDA (PMID:26268696) UniProt PMID:26268696 NCBI chr 4:41,935,120...41,960,803
Ensembl chr 4:41,935,129...41,960,803
JBrowse link
regulation of ATF6-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSPA5 heat shock protein family A (Hsp70) member 5 involved_in TAS (PMID:22934019) ParkinsonsUK-UCL PMID:22934019 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382
JBrowse link
regulation of IRE1-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COPS5 COP9 signalosome subunit 5 involved_in IMP (PMID:15234121) ParkinsonsUK-UCL PMID:15234121 NCBI chr 8:67,043,079...67,062,133
Ensembl chr 8:67,043,079...67,083,783
JBrowse link
G FICD FIC domain protein adenylyltransferase involved_in IDA (PMID:25601083) UniProt PMID:25601083 NCBI chr12:108,515,277...108,521,210
Ensembl chr12:108,515,277...108,525,837
JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 involved_in TAS (PMID:22934019) ParkinsonsUK-UCL PMID:22934019 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382
JBrowse link
regulation of PERK-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSPA5 heat shock protein family A (Hsp70) member 5 involved_in TAS (PMID:22934019) ParkinsonsUK-UCL PMID:22934019 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18526
    regulation of biological process 12358
      regulation of response to stimulus 4175
        regulation of signal transduction 3159
          regulation of endoplasmic reticulum unfolded protein response 32
            negative regulation of endoplasmic reticulum unfolded protein response + 17
            positive regulation of endoplasmic reticulum unfolded protein response + 14
            regulation of ATF6-mediated unfolded protein response + 4
            regulation of IRE1-mediated unfolded protein response + 16
            regulation of PERK-mediated unfolded protein response + 11
Path 2
Term Annotations click to browse term
  biological_process 18526
    response to stimulus 9783
      cellular response to stimulus 8102
        cellular response to chemical stimulus 3662
          cellular response to organic substance 2993
            cellular response to topologically incorrect protein 125
              cellular response to unfolded protein 105
                endoplasmic reticulum unfolded protein response 81
                  regulation of endoplasmic reticulum unfolded protein response 32
                    negative regulation of endoplasmic reticulum unfolded protein response + 17
                    positive regulation of endoplasmic reticulum unfolded protein response + 14
                    regulation of ATF6-mediated unfolded protein response + 4
                    regulation of IRE1-mediated unfolded protein response + 16
                    regulation of PERK-mediated unfolded protein response + 11
paths to the root