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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of endoplasmic reticulum unfolded protein response
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Accession:GO:1900101 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of endoplasmic reticulum unfolded protein response.
Synonyms:exact_synonym: regulation of ER unfolded protein response;   regulation of erUPR
 related_synonym: regulation of SREBP-mediated signalling pathway


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regulation of endoplasmic reticulum unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PIGBOS1 PIGB opposite strand 1 involved_in ISO (PMID:31653868) UniProt PMID:31653868 NCBI chr30:20,716,509...20,718,608 JBrowse link
negative regulation of ATF6-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATF6B activating transcription factor 6 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:1,515,186...1,525,165
Ensembl chr12:1,515,503...1,525,110
JBrowse link
G WFS1 wolframin ER transmembrane glycoprotein involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:38,451,722...38,466,481
Ensembl chr13:38,451,710...38,475,827
JBrowse link
negative regulation of endoplasmic reticulum unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CREBRF CREB3 regulatory factor involved_in ISO (PMID:18391022) UniProt PMID:18391022 NCBI chr 4:39,308,429...39,366,031
Ensembl chr 4:39,313,512...39,365,953
JBrowse link
G XBP1 X-box binding protein 1 involved_in ISO (PMID:25239945) UniProt PMID:25239945 NCBI chr26:22,162,675...22,168,149
Ensembl chr26:22,163,222...22,168,105
JBrowse link
negative regulation of IRE1-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BFAR bifunctional apoptosis regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:28,593,931...28,624,867
Ensembl chr 6:28,594,709...28,624,759
JBrowse link
G DDRGK1 DDRGK domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:18,085,865...18,098,868
Ensembl chr24:18,084,725...18,097,157
JBrowse link
G PDIA6 protein disulfide isomerase family A member 6 involved_in ISO (MGI:5571560|PMID:24508390) WB PMID:24508390 MGI:5571560 NCBI chr17:7,653,834...7,674,136
Ensembl chr17:7,654,175...7,685,999
JBrowse link
G UFL1 UFM1 specific ligase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:54,988,200...55,023,414
Ensembl chr12:54,988,264...55,021,626
JBrowse link
negative regulation of PERK-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA7 ATP binding cassette subfamily A member 7 involved_in ISO (MGI:5774886|PMID:27030769) ARUK-UCL PMID:27030769 MGI:5774886 NCBI chr20:57,668,371...57,684,111
Ensembl chr20:57,667,706...57,677,342
JBrowse link
G NCK1 NCK adaptor protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:33,297,660...33,374,025
Ensembl chr23:33,297,756...33,372,534
JBrowse link
G NCK2 NCK adaptor protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:37,584,351...37,734,388
Ensembl chr10:37,585,565...37,732,994
JBrowse link
G PTPN1 protein tyrosine phosphatase non-receptor type 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:36,936,469...37,010,929
Ensembl chr24:36,936,298...37,003,720
JBrowse link
positive regulation of ATF6-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATF6 activating transcription factor 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr38:20,705,167...20,903,852
Ensembl chr38:20,709,038...20,903,814
JBrowse link
positive regulation of endoplasmic reticulum unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAK1 BCL2 antagonist/killer 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:2,950,359...2,957,604
Ensembl chr12:2,948,364...2,957,018
JBrowse link
G BAX BCL2 associated X, apoptosis regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:107,423,388...107,426,464
Ensembl chr 1:107,422,424...107,426,464
JBrowse link
G ERN1 endoplasmic reticulum to nucleus signaling 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:11,930,614...12,006,724
Ensembl chr 9:11,934,965...12,006,814
JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:53,447,802...53,527,563
Ensembl chr 2:53,448,286...53,524,970
JBrowse link
G XBP1 X-box binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:22,162,675...22,168,149
Ensembl chr26:22,163,222...22,168,105
JBrowse link
positive regulation of IRE1-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGR2 anterior gradient 2, protein disulphide isomerase family member involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:31,303,784...31,316,752
Ensembl chr14:31,305,567...31,316,686
JBrowse link
G TMEM33 transmembrane protein 33 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:39,013,799...39,039,059
Ensembl chr13:39,013,855...39,052,547
JBrowse link
positive regulation of PERK-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGR2 anterior gradient 2, protein disulphide isomerase family member involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:31,303,784...31,316,752
Ensembl chr14:31,305,567...31,316,686
JBrowse link
G BOK BCL2 family apoptosis regulator BOK involved_in ISO (MGI:5648772|PMID:26015568) UniProt PMID:26015568 MGI:5648772 NCBI chr25:51,449,700...51,450,967 JBrowse link
G PTPN2 protein tyrosine phosphatase non-receptor type 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:78,160,564...78,252,382
Ensembl chr 7:78,160,589...78,252,719
JBrowse link
G TMEM33 transmembrane protein 33 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:39,013,799...39,039,059
Ensembl chr13:39,013,855...39,052,547
JBrowse link
regulation of IRE1-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COPS5 COP9 signalosome subunit 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr29:16,562,234...16,579,082
Ensembl chr29:16,562,234...16,578,847
JBrowse link
G FICD FIC domain protein adenylyltransferase involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:18,347,393...18,353,081
Ensembl chr26:18,348,526...18,353,665
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16215
    regulation of biological process 11036
      regulation of response to stimulus 3727
        regulation of signal transduction 2845
          regulation of endoplasmic reticulum unfolded protein response 24
            negative regulation of endoplasmic reticulum unfolded protein response + 12
            positive regulation of endoplasmic reticulum unfolded protein response + 10
            regulation of ATF6-mediated unfolded protein response + 3
            regulation of IRE1-mediated unfolded protein response + 8
            regulation of PERK-mediated unfolded protein response + 8
Path 2
Term Annotations click to browse term
  biological_process 16215
    response to stimulus 8654
      cellular response to stimulus 7302
        cellular response to chemical stimulus 3346
          cellular response to organic substance 2745
            cellular response to topologically incorrect protein 113
              cellular response to unfolded protein 93
                endoplasmic reticulum unfolded protein response 75
                  regulation of endoplasmic reticulum unfolded protein response 24
                    negative regulation of endoplasmic reticulum unfolded protein response + 12
                    positive regulation of endoplasmic reticulum unfolded protein response + 10
                    regulation of ATF6-mediated unfolded protein response + 3
                    regulation of IRE1-mediated unfolded protein response + 8
                    regulation of PERK-mediated unfolded protein response + 8
paths to the root