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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of endoplasmic reticulum unfolded protein response
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Accession:GO:1900101 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of endoplasmic reticulum unfolded protein response.
Synonyms:exact_synonym: regulation of ER unfolded protein response;   regulation of erUPR
 related_synonym: regulation of SREBP-mediated signalling pathway


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regulation of endoplasmic reticulum unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PIGBOS1 PIGB opposite strand 1 involved_in ISO (PMID:31653868) UniProt PMID:31653868 NCBI chr15:34,286,568...34,325,835
Ensembl chr15:52,610,151...52,610,315
JBrowse link
negative regulation of ATF6-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATF6B activating transcription factor 6 beta involved_in ISO (PMID:9837962) UniProt PMID:9837962 NCBI chr 6:31,762,161...31,775,136
Ensembl chr 6:32,643,124...32,655,617
JBrowse link
G WFS1 wolframin ER transmembrane glycoprotein involved_in ISO PMID:20160352
(PMID:20160352)
ParkinsonsUK-UCL PMID:20160352 RGD:10047363 Ensembl chr 4:6,345,864...6,379,287 JBrowse link
negative regulation of endoplasmic reticulum unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CREBRF CREB3 regulatory factor involved_in ISO (PMID:18391022) UniProt PMID:18391022 NCBI chr 5:168,409,668...168,492,678
Ensembl chr 5:175,318,674...175,403,334
JBrowse link
G XBP1 X-box binding protein 1 involved_in ISO (PMID:25239945) UniProt PMID:25239945 NCBI chr22:9,863,479...9,869,491
Ensembl chr22:27,567,041...27,571,943
JBrowse link
negative regulation of IRE1-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BFAR bifunctional apoptosis regulator involved_in ISO (PMID:21068390) ParkinsonsUK-UCL PMID:21068390 NCBI chr16:13,558,912...13,597,023
Ensembl chr16:14,980,615...15,018,310
JBrowse link
G DDRGK1 DDRGK domain containing 1 involved_in ISO (PMID:28128204), (PMID:32160526)
(MGI:5912977|PMID:28128204)
UniProt PMID:28128204 PMID:32160526 MGI:5912977 NCBI chr20:3,276,292...3,290,433
Ensembl chr20:3,038,779...3,052,789
JBrowse link
G PDIA6 protein disulfide isomerase family A member 6 involved_in ISO (MGI:5571560|PMID:24508390) WB PMID:24508390 MGI:5571560 NCBI chr2A:10,781,671...10,809,235
Ensembl chr2A:10,934,756...10,986,200
JBrowse link
G UFL1 UFM1 specific ligase 1 involved_in ISO (PMID:32160526) UniProt PMID:32160526 NCBI chr 6:94,356,440...94,389,920
Ensembl chr 6:98,242,756...98,274,377
JBrowse link
negative regulation of PERK-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA7 ATP binding cassette subfamily A member 7 involved_in ISO (MGI:5774886|PMID:27030769) ARUK-UCL PMID:27030769 MGI:5774886 NCBI chr19:62,811...77,897
Ensembl chr19:1,018,095...1,042,104
JBrowse link
G NCK1 NCK adaptor protein 1 involved_in ISO (PMID:14676213)
(MGI:5613478|PMID:14676213)
ParkinsonsUK-UCL PMID:14676213 MGI:5613478 NCBI chr 3:133,902,463...133,990,414
Ensembl chr 3:141,427,870...141,451,444
JBrowse link
G NCK2 NCK adaptor protein 2 involved_in ISO (MGI:5613478|PMID:14676213) ParkinsonsUK-UCL PMID:14676213 MGI:5613478 NCBI chr2A:95,939,197...96,089,163
Ensembl chr2A:106,898,547...106,976,363
JBrowse link
G PTPN1 protein tyrosine phosphatase non-receptor type 1 involved_in ISO (PMID:21216966)
(MGI:5619464|PMID:21216966)
ParkinsonsUK-UCL PMID:21216966 MGI:5619464 NCBI chr20:46,854,918...46,929,509
Ensembl chr20:47,983,098...48,057,421
JBrowse link
positive regulation of ATF6-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATF6 activating transcription factor 6 involved_in ISO (PMID:9837962) UniProt PMID:9837962 NCBI chr 1:137,178,629...137,382,256
Ensembl chr 1:140,977,750...141,176,725
JBrowse link
positive regulation of endoplasmic reticulum unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAK1 BCL2 antagonist/killer 1 involved_in ISO (PMID:16645094) UniProt PMID:16645094 NCBI chr 6:33,146,998...33,154,755
Ensembl chr 6:34,255,769...34,263,211
JBrowse link
G BAX BCL2 associated X, apoptosis regulator involved_in ISO (PMID:16645094) UniProt PMID:16645094 NCBI chr19:45,955,926...45,962,870
Ensembl chr19:54,793,594...54,800,468
JBrowse link
G ERN1 endoplasmic reticulum to nucleus signaling 1 involved_in ISO (PMID:16645094), (PMID:28128204) UniProt PMID:16645094 PMID:28128204 NCBI chr17:58,132,889...58,224,012
Ensembl chr17:63,226,949...63,317,825
JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 involved_in ISO (PMID:20348923) UniProt PMID:20348923 NCBI chr 5:45,701,219...45,786,652
Ensembl chr 5:47,267,286...47,350,960
JBrowse link
G XBP1 X-box binding protein 1 involved_in ISO (PMID:16645094) UniProt PMID:16645094 NCBI chr22:9,863,479...9,869,491
Ensembl chr22:27,567,041...27,571,943
JBrowse link
positive regulation of IRE1-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGR2 anterior gradient 2, protein disulphide isomerase family member involved_in ISO (PMID:23220234) UniProt PMID:23220234 NCBI chr 7:17,446,275...17,489,802
Ensembl chr 7:16,773,281...16,785,879
JBrowse link
G TMEM33 transmembrane protein 33 involved_in ISO (PMID:26268696) UniProt PMID:26268696 NCBI chr 4:36,260,669...36,281,546
Ensembl chr 4:42,108,335...42,127,575
JBrowse link
positive regulation of PERK-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGR2 anterior gradient 2, protein disulphide isomerase family member involved_in ISO (PMID:23220234) UniProt PMID:23220234 NCBI chr 7:17,446,275...17,489,802
Ensembl chr 7:16,773,281...16,785,879
JBrowse link
G BOK BCL2 family apoptosis regulator BOK involved_in ISO (MGI:5648772|PMID:26015568) UniProt PMID:26015568 MGI:5648772 NCBI chr2B:128,832,458...128,847,918
Ensembl chr2B:247,626,494...247,640,238
JBrowse link
G PTPN2 protein tyrosine phosphatase non-receptor type 2 involved_in ISO (MGI:5619464|PMID:21216966) ParkinsonsUK-UCL PMID:21216966 MGI:5619464 NCBI chr18:1,440,837...1,538,501
Ensembl chr18:16,562,052...16,659,570
JBrowse link
G TMEM33 transmembrane protein 33 involved_in ISO (PMID:26268696) UniProt PMID:26268696 NCBI chr 4:36,260,669...36,281,546
Ensembl chr 4:42,108,335...42,127,575
JBrowse link
regulation of IRE1-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COPS5 COP9 signalosome subunit 5 involved_in ISO (PMID:15234121) ParkinsonsUK-UCL PMID:15234121 NCBI chr 8:63,586,062...63,605,213
Ensembl chr 8:65,247,950...65,266,511
JBrowse link
G FICD FIC domain protein adenylyltransferase involved_in ISO (PMID:25601083) UniProt PMID:25601083 NCBI chr12:106,086,792...106,092,765
Ensembl chr12:109,482,945...109,488,958
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12616
    regulation of biological process 8690
      regulation of response to stimulus 3401
        regulation of signal transduction 2592
          regulation of endoplasmic reticulum unfolded protein response 24
            negative regulation of endoplasmic reticulum unfolded protein response + 12
            positive regulation of endoplasmic reticulum unfolded protein response + 10
            regulation of ATF6-mediated unfolded protein response + 3
            regulation of IRE1-mediated unfolded protein response + 8
            regulation of PERK-mediated unfolded protein response + 8
Path 2
Term Annotations click to browse term
  biological_process 12616
    response to stimulus 6804
      cellular response to stimulus 5389
        cellular response to chemical stimulus 2855
          cellular response to organic substance 2335
            cellular response to topologically incorrect protein 86
              cellular response to unfolded protein 73
                endoplasmic reticulum unfolded protein response 61
                  regulation of endoplasmic reticulum unfolded protein response 24
                    negative regulation of endoplasmic reticulum unfolded protein response + 12
                    positive regulation of endoplasmic reticulum unfolded protein response + 10
                    regulation of ATF6-mediated unfolded protein response + 3
                    regulation of IRE1-mediated unfolded protein response + 8
                    regulation of PERK-mediated unfolded protein response + 8
paths to the root