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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of endoplasmic reticulum unfolded protein response
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Accession:GO:1900101 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of endoplasmic reticulum unfolded protein response.
Synonyms:exact_synonym: regulation of ER unfolded protein response;   regulation of erUPR
 related_synonym: regulation of SREBP-mediated signalling pathway


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regulation of endoplasmic reticulum unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pigbos1 PIGB opposite strand 1 involved_in ISO
ISS
(PMID:31653868)
GO_REF:0000024
RGD
UniProt
PMID:31653868 GO_REF:0000024 NCBI chr 8:79,715,337...79,719,706 JBrowse link
negative regulation of ATF6-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf6b activating transcription factor 6 beta involved_in ISO (PMID:9837962) RGD PMID:9837962 NCBI chr20:4,414,283...4,422,283
Ensembl chr20:4,414,276...4,422,283
JBrowse link
G Wfs1 wolframin ER transmembrane glycoprotein involved_in IGI
ISO
PMID:20160352
(PMID:20160352)
RGD PMID:20160352, PMID:20160352 RGD:10047363 NCBI chr14:78,640,707...78,665,224
Ensembl chr14:78,640,620...78,665,966
JBrowse link
negative regulation of endoplasmic reticulum unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crebrf CREB3 regulatory factor involved_in ISO (PMID:18391022) RGD PMID:18391022 NCBI chr10:16,693,846...16,753,162
Ensembl chr10:16,694,792...16,752,205
JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISO (PMID:25239945) RGD PMID:25239945 NCBI chr14:85,753,736...85,758,820
Ensembl chr14:85,753,760...85,758,145
JBrowse link
negative regulation of IRE1-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bfar bifunctional apoptosis regulator involved_in ISO (PMID:21068390) RGD PMID:21068390 NCBI chr10:1,464,783...1,497,653
Ensembl chr10:1,464,765...1,497,653
JBrowse link
G Ddrgk1 DDRGK domain containing 1 involved_in ISO (PMID:28128204), (PMID:32160526)
(MGI:5912977|PMID:28128204)
RGD PMID:28128204 PMID:32160526 MGI:5912977 NCBI chr 3:123,195,580...123,206,828
Ensembl chr 3:123,195,580...123,206,828
JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 6:64,165,913...64,170,122
Ensembl chr 6:64,165,913...64,170,151
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Pdia6 protein disulfide isomerase family A, member 6 involved_in ISO (MGI:5571560|PMID:24508390) RGD PMID:24508390 MGI:5571560 NCBI chr 6:42,568,269...42,585,654
Ensembl chr 6:42,568,220...42,585,652
JBrowse link
G Ufl1 Ufm1-specific ligase 1 involved_in ISO
ISS
(PMID:32160526)
GO_REF:0000024
RGD
UniProt
PMID:32160526 GO_REF:0000024 NCBI chr 5:39,616,479...39,650,894
Ensembl chr 5:39,615,956...39,650,895
JBrowse link
negative regulation of PERK-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca7 ATP binding cassette subfamily A member 7 involved_in ISO (MGI:5774886|PMID:27030769) RGD PMID:27030769 MGI:5774886 NCBI chr 7:12,742,433...12,762,423
Ensembl chr 7:12,742,433...12,762,341
JBrowse link
G Nck1 NCK adaptor protein 1 involved_in ISO (PMID:14676213)
UniProtKB:O55033 (MGI:5613478|PMID:14676213)
RGD PMID:14676213 MGI:5613478 NCBI chr 8:108,787,797...108,847,779
Ensembl chr 8:108,787,798...108,847,779
JBrowse link
G Nck2 NCK adaptor protein 2 involved_in ISO UniProtKB:Q99M51 (MGI:5613478|PMID:14676213) RGD PMID:14676213 MGI:5613478 NCBI chr 9:50,246,767...50,373,307
Ensembl chr 9:50,247,692...50,373,284
JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 involved_in ISO (PMID:21216966)
(MGI:5619464|PMID:21216966)
RGD PMID:21216966 MGI:5619464 NCBI chr 3:164,665,462...164,711,936
Ensembl chr 3:164,665,532...164,711,848
JBrowse link
positive regulation of ATF6-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf6 activating transcription factor 6 involved_in ISO (PMID:9837962) RGD PMID:9837962 NCBI chr13:89,053,457...89,242,531
Ensembl chr13:89,055,983...89,242,443
JBrowse link
positive regulation of endoplasmic reticulum unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bak1 BCL2-antagonist/killer 1 involved_in ISO (PMID:16645094) RGD PMID:16645094 NCBI chr20:5,609,620...5,618,899
Ensembl chr20:5,609,625...5,618,260
JBrowse link
G Bax BCL2 associated X, apoptosis regulator involved_in ISO
IEA
ISS
(PMID:16645094)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:16645094 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 involved_in ISO (PMID:16645094), (PMID:28128204) RGD PMID:16645094 PMID:28128204 NCBI chr10:94,588,555...94,682,072
Ensembl chr10:94,588,555...94,681,914
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 involved_in ISO
IEA
ISS
(PMID:20348923)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:20348923 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:31,742,326...31,826,882
Ensembl chr 2:31,745,088...31,826,867
JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISO
IEA
(PMID:16645094)
GO_REF:0000107
RGD
Ensembl
PMID:16645094 GO_REF:0000107 NCBI chr14:85,753,736...85,758,820
Ensembl chr14:85,753,760...85,758,145
JBrowse link
positive regulation of IRE1-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agr2 anterior gradient 2, protein disulphide isomerase family member involved_in ISO (PMID:23220234) RGD PMID:23220234 NCBI chr 6:55,465,782...55,487,087
Ensembl chr 6:55,465,782...55,487,714
JBrowse link
G Tmem33 transmembrane protein 33 involved_in ISO
IEA
ISS
(PMID:26268696)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:26268696 GO_REF:0000024 GO_REF:0000107 NCBI chr14:42,537,352...42,559,580
Ensembl chr14:42,535,701...42,560,174
JBrowse link
positive regulation of PERK-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agr2 anterior gradient 2, protein disulphide isomerase family member involved_in ISO (PMID:23220234) RGD PMID:23220234 NCBI chr 6:55,465,782...55,487,087
Ensembl chr 6:55,465,782...55,487,714
JBrowse link
G Bok BCL2 family apoptosis regulator BOK involved_in ISS
ISO
GO_REF:0000024
(MGI:5648772|PMID:26015568)
UniProt
RGD
PMID:26015568 GO_REF:0000024 MGI:5648772 NCBI chr 9:100,829,593...100,840,498
Ensembl chr 9:100,829,552...100,840,504
JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in ISO (MGI:5619464|PMID:21216966) RGD PMID:21216966 MGI:5619464 NCBI chr18:63,415,298...63,489,240
Ensembl chr18:63,415,306...63,488,027
JBrowse link
G Tmem33 transmembrane protein 33 involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:26268696)
Ensembl
UniProt
RGD
PMID:26268696 GO_REF:0000024 GO_REF:0000107 NCBI chr14:42,537,352...42,559,580
Ensembl chr14:42,535,701...42,560,174
JBrowse link
regulation of IRE1-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cops5 COP9 signalosome subunit 5 involved_in ISO (PMID:15234121) RGD PMID:15234121 NCBI chr 5:8,876,090...8,894,345
Ensembl chr 5:8,876,044...8,894,339
JBrowse link
G Ficd FIC domain protein adenylyltransferase involved_in ISO
ISS
(PMID:25601083)
GO_REF:0000024
RGD
UniProt
PMID:25601083 GO_REF:0000024 NCBI chr12:48,658,283...48,663,175
Ensembl chr12:48,658,283...48,663,143
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19612
    regulation of biological process 12857
      regulation of response to stimulus 3982
        regulation of signal transduction 2964
          regulation of endoplasmic reticulum unfolded protein response 26
            negative regulation of endoplasmic reticulum unfolded protein response + 14
            positive regulation of endoplasmic reticulum unfolded protein response + 10
            regulation of ATF6-mediated unfolded protein response + 3
            regulation of IRE1-mediated unfolded protein response + 10
            regulation of PERK-mediated unfolded protein response + 8
Path 2
Term Annotations click to browse term
  biological_process 19612
    response to stimulus 10435
      cellular response to stimulus 8799
        cellular response to chemical stimulus 3521
          cellular response to organic substance 2861
            cellular response to topologically incorrect protein 125
              cellular response to unfolded protein 103
                endoplasmic reticulum unfolded protein response 75
                  regulation of endoplasmic reticulum unfolded protein response 26
                    negative regulation of endoplasmic reticulum unfolded protein response + 14
                    positive regulation of endoplasmic reticulum unfolded protein response + 10
                    regulation of ATF6-mediated unfolded protein response + 3
                    regulation of IRE1-mediated unfolded protein response + 10
                    regulation of PERK-mediated unfolded protein response + 8
paths to the root