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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of ruffle assembly
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Accession:GO:1900029 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of ruffle assembly.
Synonyms:exact_synonym: positive regulation of membrane ruffle formation;   positive regulation of membrane ruffling;   up regulation of membrane ruffle formation;   up regulation of membrane ruffling
 related_synonym: up regulation of ruffle assembly


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positive regulation of ruffle assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Carmil2 capping protein regulator and myosin 1 linker 2 involved_in ISO
IEA		 (PMID:26466680), (PMID:26578515)
GO_REF:0000107		 RGD
Ensembl		 PMID:26466680 PMID:26578515 GO_REF:0000107 NCBI chr19:50,481,911...50,496,672
Ensembl chr19:33,574,257...33,586,965 		JBrowse link
G Cobl cordon-bleu WH2 repeat protein involved_in IEA
ISO		 GO_REF:0000107
(PMID:17956734)		 Ensembl
RGD		 PMID:17956734 GO_REF:0000107 NCBI chr14:86,828,137...87,060,682
Ensembl chr14:86,828,139...87,060,800 		JBrowse link
G Cyfip1 cytoplasmic FMR1 interacting protein 1 IMP RGD PMID:16260607 RGD:11557987 NCBI chr 1:115,842,754...115,935,163
Ensembl chr 1:106,711,016...106,799,386 		JBrowse link
G Def8 differentially expressed in FDCP 8 homolog involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:27777970)		 UniProt
Ensembl
RGD		 PMID:27777970 GO_REF:0000024 GO_REF:0000107 NCBI chr19:51,474,783...51,495,638
Ensembl chr19:51,474,878...51,495,638 		JBrowse link
G Eps8 EGFR pathway substrate 8, signaling adaptor involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:172,119,497...172,291,670
Ensembl chr 4:170,388,378...170,486,873 		JBrowse link
G Eps8l1 EPS8 signaling adaptor L1 involved_in ISO
IEA
IBA		 UniProtKB:Q08509|UniProtKB:Q8R5F8|UniProtKB:Q91WL0|UniProtKB:Q99K30 (PMID:14565974)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:14565974 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:78,386,916...78,409,972
Ensembl chr 1:69,344,243...69,363,524 		JBrowse link
G Eps8l2 EPS8 signaling adaptor L2 involved_in ISO
IEA
IBA		 UniProtKB:Q08509|UniProtKB:Q8R5F8|UniProtKB:Q91WL0|UniProtKB:Q99K30 (PMID:14565974)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:14565974 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:196,446,260...196,471,544
Ensembl chr 1:196,446,287...196,471,541 		JBrowse link
G Eps8l3 EPS8 signaling adaptor L3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:198,202,862...198,216,255
Ensembl chr 2:195,514,692...195,528,085 		JBrowse link
G Fam98a family with sequence similarity 98, member A involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:27777970)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:27777970 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:19,874,082...19,888,744
Ensembl chr 6:19,874,071...19,888,742 		JBrowse link
G Hras HRas proto-oncogene, GTPase involved_in ISO (PMID:23027131) RGD PMID:23027131 NCBI chr 1:205,712,625...205,729,406
Ensembl chr 1:196,296,263...196,300,615 		JBrowse link
G Ndel1 nudE neurodevelopment protein 1-like 1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:27777970)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:27777970 GO_REF:0000024 GO_REF:0000107 NCBI chr10:54,001,435...54,080,909
Ensembl chr10:53,516,491...53,570,907 		JBrowse link
G Nlgn1 neuroligin 1 involved_in IDA PMID:12930820 BHF-UCL PMID:12930820 RGD:8554754 NCBI chr 2:110,184,987...111,110,316
Ensembl chr 2:108,257,824...109,002,464 		JBrowse link
G P2ry12 purinergic receptor P2Y12 involved_in IMP PMID:17299767 ARUK-UCL PMID:17299767 RGD:13673751 NCBI chr 2:145,631,487...145,673,194
Ensembl chr 2:143,481,430...143,523,361 		JBrowse link
G Pfn1 profilin 1 involved_in ISO
IEA		 (PMID:23153535)
GO_REF:0000107		 RGD
Ensembl		 PMID:23153535 GO_REF:0000107 NCBI chr10:55,863,882...55,866,587
Ensembl chr10:55,365,262...55,527,631 		JBrowse link
G Plekhm1 pleckstrin homology and RUN domain containing M1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:27777970)		 UniProt
Ensembl
RGD		 PMID:27777970 GO_REF:0000024 GO_REF:0000107 NCBI chr10:88,814,699...88,876,570
Ensembl chr10:88,314,651...88,362,412 		JBrowse link
G Rac1 Rac family small GTPase 1 acts_upstream_of_or_within ISO (PMID:15467718) RGD PMID:15467718 NCBI chr12:16,150,411...16,170,864
Ensembl chr12:11,036,698...11,057,251 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    positive regulation of biological process 6766
      positive regulation of cellular process 6424
        positive regulation of cellular component biogenesis 565
          positive regulation of plasma membrane bounded cell projection assembly 121
            positive regulation of ruffle assembly 16
Path 2
Term Annotations click to browse term
  biological_process 20558
    cellular process 19550
      cellular component organization or biogenesis 7104
        cellular component organization 6817
          cellular component assembly 3214
            cell projection assembly 675
              regulation of cell projection assembly 248
                regulation of plasma membrane bounded cell projection assembly 245
                  positive regulation of plasma membrane bounded cell projection assembly 121
                    positive regulation of ruffle assembly 16
paths to the root