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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of ruffle assembly
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Accession:GO:1900027 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of ruffle assembly.
Synonyms:exact_synonym: regulation of membrane ruffle formation;   regulation of membrane ruffling



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regulation of ruffle assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav1 caveolin 1 involved_in ISO (PMID:24625804) RGD PMID:24625804 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Coro1c coronin 1C involved_in ISO UniProtKB:Q8BK67 (MGI:5621257|PMID:25074804) RGD PMID:25074804 MGI:5621257 NCBI chr12:42,712,960...42,785,179
Ensembl chr12:42,712,991...42,785,179
JBrowse link
G Icam1 intercellular adhesion molecule 1 acts_upstream_of_or_within ISO (MGI:5486234|PMID:23372835) RGD PMID:23372835 MGI:5486234 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G LOC100910107 ubiquitin carboxyl-terminal hydrolase DUB-1-like involved_in ISO (PMID:21448158) RGD PMID:21448158 NCBI chr 1:159,151,417...159,155,192
Ensembl chr 1:159,151,432...159,155,192
JBrowse link
G P2rx4 purinergic receptor P2X 4 NOT|involved_in IMP PMID:17299767 ARUK-UCL PMID:17299767 RGD:13673751 NCBI chr12:33,844,609...33,862,265
Ensembl chr12:33,844,396...33,862,253
JBrowse link
G Rcc2 regulator of chromosome condensation 2 involved_in ISO UniProtKB:Q9WUM4 (MGI:5621257|PMID:25074804) RGD PMID:25074804 MGI:5621257 NCBI chr 5:152,994,406...153,017,223
Ensembl chr 5:152,993,665...153,017,205
JBrowse link
G Rdx radixin involved_in ISO (PMID:22467863) RGD PMID:22467863 NCBI chr 8:52,379,494...52,437,673
Ensembl chr 8:52,379,494...52,437,678
JBrowse link
G Rhog ras homolog family member G acts_upstream_of_or_within ISO (MGI:5486234|PMID:23372835) RGD PMID:23372835 MGI:5486234 NCBI chr 1:156,618,713...156,630,710
Ensembl chr 1:156,615,349...156,631,257
JBrowse link
G Sh3yl1 SH3 and SYLF domain containing 1 acts_upstream_of_or_within ISO (MGI:5008671|PMID:21624956) RGD PMID:21624956 MGI:5008671 NCBI chr 6:47,522,098...47,565,858
Ensembl chr 6:47,522,091...47,565,858
JBrowse link
G Wdpcp WD repeat containing planar cell polarity effector acts_upstream_of_or_within ISO MGI:5558098 (MGI:5544506|PMID:24302887) RGD PMID:24302887 MGI:5544506 NCBI chr14:95,645,955...95,977,120
Ensembl chr14:95,646,038...95,977,113
JBrowse link
negative regulation of ruffle assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgap24 Rho GTPase activating protein 24 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:5297730|PMID:21911940)
RGD PMID:21911940 PMID:21873635 MGI:5297730, RGD:13792537 NCBI chr14:6,800,631...7,184,001
Ensembl chr14:6,800,631...7,183,823
JBrowse link
G Evl Enah/Vasp-like involved_in ISO (PMID:23153535) RGD PMID:23153535 NCBI chr 6:127,473,119...127,594,342
Ensembl chr 6:127,474,543...127,594,344
JBrowse link
G Kank1 KN motif and ankyrin repeat domains 1 involved_in ISO (PMID:19171758) RGD PMID:19171758 NCBI chr 1:222,877,962...223,074,514
Ensembl chr 1:222,877,622...223,074,514
JBrowse link
G Pfn2 profilin 2 involved_in ISO
IEA
(PMID:23153535)
GO_REF:0000107
(MGI:5545940|PMID:23153535)
RGD
Ensembl
PMID:23153535 GO_REF:0000107 MGI:5545940 NCBI chr 2:142,067,102...142,072,938
Ensembl chr 2:142,067,104...142,072,938
JBrowse link
G Stap1 signal transducing adaptor family member 1 involved_in ISO (MGI:3831067|PMID:19100238) RGD PMID:19100238 MGI:3831067 NCBI chr14:21,950,466...21,981,395
Ensembl chr14:21,952,496...21,981,245
JBrowse link
G Tacstd2 tumor-associated calcium signal transducer 2 involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:5315060|PMID:22194864)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:22194864 GO_REF:0000024 GO_REF:0000107 MGI:5315060 NCBI chr 4:96,707,950...96,709,650
Ensembl chr 4:96,707,951...96,709,650
JBrowse link
positive regulation of ruffle assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Carmil2 capping protein regulator and myosin 1 linker 2 involved_in ISO (PMID:26466680), (PMID:26578515) RGD PMID:26466680 PMID:26578515 NCBI chr19:33,571,255...33,586,783
Ensembl chr19:33,574,257...33,586,965
JBrowse link
G Cobl cordon-bleu WH2 repeat protein involved_in ISO (MGI:3765263|PMID:17956734) RGD PMID:17956734 MGI:3765263 NCBI chr14:86,828,137...87,060,682
Ensembl chr14:86,828,139...87,060,800
JBrowse link
G Cyfip1 cytoplasmic FMR1 interacting protein 1 IMP RGD PMID:16260607 RGD:11557987 NCBI chr 1:106,710,924...106,799,393
Ensembl chr 1:106,711,016...106,799,386
JBrowse link
G Def8 differentially expressed in FDCP 8 homolog involved_in ISS
ISO
GO_REF:0000024
(MGI:5806241|PMID:27777970)
UniProt
RGD
PMID:27777970 GO_REF:0000024 MGI:5806241 NCBI chr19:51,474,783...51,495,638
Ensembl chr19:51,474,878...51,495,638
JBrowse link
G Eps8 epidermal growth factor receptor pathway substrate 8 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:170,388,378...170,486,873
Ensembl chr 4:170,388,378...170,486,873
JBrowse link
G Eps8l1 EPS8-like 1 involved_in ISO
IBA
UniProtKB:Q08509|UniProtKB:Q8R5F8|UniProtKB:Q91WL0|UniProtKB:Q99K30 (PMID:14565974)
PMID:21873635
RGD PMID:14565974 PMID:21873635 RGD:13792537 NCBI chr 1:69,343,202...69,359,778
Ensembl chr 1:69,344,243...69,363,524
JBrowse link
G Eps8l2 EPS8-like 2 involved_in IBA
ISO
PMID:21873635
UniProtKB:Q08509|UniProtKB:Q8R5F8|UniProtKB:Q91WL0|UniProtKB:Q99K30 (PMID:14565974)
RGD PMID:14565974 PMID:21873635 RGD:13792537 NCBI chr 1:196,446,067...196,471,542
Ensembl chr 1:196,446,287...196,471,541
JBrowse link
G Eps8l3 EPS8 like 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 2:195,514,692...195,528,085 JBrowse link
G Fam98a family with sequence similarity 98, member A involved_in ISS
ISO
GO_REF:0000024
(MGI:5806241|PMID:27777970)
UniProt
RGD
PMID:27777970 GO_REF:0000024 MGI:5806241 NCBI chr 6:19,874,082...19,888,744
Ensembl chr 6:19,874,071...19,888,742
JBrowse link
G Hras HRas proto-oncogene, GTPase involved_in ISO (PMID:23027131) RGD PMID:23027131 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
JBrowse link
G Ndel1 nudE neurodevelopment protein 1-like 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:5806241|PMID:27777970)
UniProt
RGD
PMID:27777970 GO_REF:0000024 MGI:5806241 NCBI chr10:53,505,628...53,582,025
Ensembl chr10:53,516,491...53,570,907
JBrowse link
G Nlgn1 neuroligin 1 involved_in IDA PMID:12930820 BHF-UCL PMID:12930820 RGD:8554754 NCBI chr 2:108,256,236...109,181,530
Ensembl chr 2:108,257,824...109,002,464
JBrowse link
G P2ry12 purinergic receptor P2Y12 involved_in IMP PMID:17299767 ARUK-UCL PMID:17299767 RGD:13673751 NCBI chr 2:143,481,468...143,523,340
Ensembl chr 2:143,481,430...143,523,361
JBrowse link
G Pfn1 profilin 1 involved_in ISO (PMID:23153535) RGD PMID:23153535 NCBI chr10:55,365,263...55,367,968
Ensembl chr10:55,365,262...55,527,631
JBrowse link
G Plekhm1 pleckstrin homology and RUN domain containing M1 involved_in ISS
ISO
GO_REF:0000024
(MGI:5806241|PMID:27777970)
UniProt
RGD
PMID:27777970 GO_REF:0000024 MGI:5806241 NCBI chr10:88,313,837...88,366,182
Ensembl chr10:88,314,651...88,362,412
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19512
    regulation of biological process 12887
      regulation of cellular process 12364
        regulation of cellular component biogenesis 1065
          regulation of cell projection assembly 238
            regulation of plasma membrane bounded cell projection assembly 235
              regulation of ruffle assembly 31
                negative regulation of ruffle assembly 6
                positive regulation of ruffle assembly 15
Path 2
Term Annotations click to browse term
  biological_process 19512
    cellular process 18319
      cellular component organization or biogenesis 6656
        cellular component organization 6418
          cell projection organization 1767
            plasma membrane bounded cell projection organization 1727
              ruffle organization 59
                ruffle assembly 47
                  regulation of ruffle assembly 31
                    negative regulation of ruffle assembly 6
                    positive regulation of ruffle assembly 15
paths to the root