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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of ruffle assembly
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Accession:GO:1900027 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of ruffle assembly.
Synonyms:exact_synonym: regulation of membrane ruffle formation;   regulation of membrane ruffling
 never_in_taxon: NCBITaxon:2 ! Bacteria;   NCBITaxon:33090 ! Viridiplantae;   NCBITaxon:4751 ! Fungi


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regulation of ruffle assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav1 caveolin 1 involved_in ISO
IEA		 (PMID:24625804)
GO_REF:0000107		 RGD
Ensembl		 PMID:24625804 GO_REF:0000107 NCBI chr 4:46,606,538...46,639,616
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Coro1c coronin 1C involved_in ISO
IEA		 UniProtKB:Q8BK67 (PMID:25074804)
GO_REF:0000107		 RGD
Ensembl		 PMID:25074804 GO_REF:0000107 NCBI chr12:48,373,573...48,445,718
Ensembl chr12:42,712,991...42,785,179 		JBrowse link
G Icam1 intercellular adhesion molecule 1 acts_upstream_of_or_within ISO (PMID:23372835) RGD PMID:23372835 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G P2rx4 purinergic receptor P2X 4 NOT|involved_in IMP PMID:17299767 ARUK-UCL PMID:17299767 RGD:13673751 NCBI chr12:39,505,438...39,523,349
Ensembl chr12:33,844,396...33,862,253 		JBrowse link
G Rcc2 regulator of chromosome condensation 2 involved_in ISO
IEA		 UniProtKB:Q9WUM4 (PMID:25074804)
GO_REF:0000107		 RGD
Ensembl		 PMID:25074804 GO_REF:0000107 NCBI chr 5:158,277,476...158,300,294
Ensembl chr 5:152,993,665...153,017,205 		JBrowse link
G Rdx radixin involved_in ISO
IEA		 (PMID:22467863)
GO_REF:0000107		 RGD
Ensembl		 PMID:22467863 GO_REF:0000107 NCBI chr 8:61,275,792...61,348,260
Ensembl chr 8:52,379,494...52,437,678 		JBrowse link
G Rhog ras homolog family member G acts_upstream_of_or_within ISO (PMID:23372835) RGD PMID:23372835 NCBI chr 1:166,030,685...166,046,254
Ensembl chr 1:156,615,349...156,631,257 		JBrowse link
G Sh3yl1 SH3 and SYLF domain containing 1 acts_upstream_of_or_within
involved_in		 ISO
IEA
IBA		 (PMID:21624956)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:21624956 GO_REF:0000033 GO_REF:0000107 NCBI chr 6:53,250,036...53,293,406
Ensembl chr 6:47,522,091...47,565,858 		JBrowse link
G Usp17la2 ubiquitin specific peptidase 17-like a2 involved_in ISO (PMID:21448158) RGD PMID:21448158 NCBI chr 1:168,563,281...168,567,056
Ensembl chr 1:159,151,432...159,155,192 		JBrowse link
G Wdpcp WD repeat containing planar cell polarity effector acts_upstream_of_or_within ISO
IEA		 MGI:5558098 (PMID:24302887)
GO_REF:0000107		 RGD
Ensembl		 PMID:24302887 GO_REF:0000107 NCBI chr14:99,847,463...100,178,392
Ensembl chr14:95,646,038...95,977,113 		JBrowse link
negative regulation of ruffle assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgap24 Rho GTPase activating protein 24 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:21911940)		 GO_Central
RGD		 PMID:21911940 GO_REF:0000033 NCBI chr14:7,105,200...7,488,437
Ensembl chr14:6,800,631...7,183,823 		JBrowse link
G Evl Enah/Vasp-like involved_in ISO
IEA		 (PMID:23153535)
GO_REF:0000107		 RGD
Ensembl		 PMID:23153535 GO_REF:0000107 NCBI chr 6:133,238,547...133,358,730
Ensembl chr 6:127,474,543...127,594,344 		JBrowse link
G Kank1 KN motif and ankyrin repeat domains 1 involved_in ISO
IEA		 (PMID:19171758)
GO_REF:0000107		 RGD
Ensembl		 PMID:19171758 GO_REF:0000107 NCBI chr 1:232,381,720...232,500,834
Ensembl chr 1:222,877,622...223,074,514 		JBrowse link
G Pfn2 profilin 2 involved_in ISO
IEA		 (PMID:23153535)
GO_REF:0000107		 RGD
Ensembl		 PMID:23153535 GO_REF:0000107 NCBI chr 2:144,217,100...144,222,936
Ensembl chr 2:142,067,104...142,072,938 		JBrowse link
G Stap1 signal transducing adaptor family member 1 involved_in ISO (PMID:19100238) RGD PMID:19100238 NCBI chr14:22,301,278...22,336,218
Ensembl chr14:21,952,496...21,981,245 		JBrowse link
G Tacstd2 tumor-associated calcium signal transducer 2 involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:22194864)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:22194864 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:98,037,620...98,039,320
Ensembl chr 4:96,707,951...96,709,650 		JBrowse link
positive regulation of ruffle assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Carmil2 capping protein regulator and myosin 1 linker 2 involved_in ISO
IEA		 (PMID:26466680), (PMID:26578515)
GO_REF:0000107		 RGD
Ensembl		 PMID:26466680 PMID:26578515 GO_REF:0000107 NCBI chr19:50,481,911...50,496,672
Ensembl chr19:33,574,257...33,586,965 		JBrowse link
G Cobl cordon-bleu WH2 repeat protein involved_in IEA
ISO		 GO_REF:0000107
(PMID:17956734)		 Ensembl
RGD		 PMID:17956734 GO_REF:0000107 NCBI chr14:86,828,137...87,060,682
Ensembl chr14:86,828,139...87,060,800 		JBrowse link
G Cyfip1 cytoplasmic FMR1 interacting protein 1 IMP RGD PMID:16260607 RGD:11557987 NCBI chr 1:115,842,754...115,935,163
Ensembl chr 1:106,711,016...106,799,386 		JBrowse link
G Def8 differentially expressed in FDCP 8 homolog involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:27777970)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:27777970 GO_REF:0000024 GO_REF:0000107 NCBI chr19:51,474,783...51,495,638
Ensembl chr19:51,474,878...51,495,638 		JBrowse link
G Eps8 EGFR pathway substrate 8, signaling adaptor involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:172,119,497...172,291,670
Ensembl chr 4:170,388,378...170,486,873 		JBrowse link
G Eps8l1 EPS8 signaling adaptor L1 involved_in ISO
IBA
IEA		 UniProtKB:Q08509|UniProtKB:Q8R5F8|UniProtKB:Q91WL0|UniProtKB:Q99K30 (PMID:14565974)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:14565974 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:78,386,916...78,409,972
Ensembl chr 1:69,344,243...69,363,524 		JBrowse link
G Eps8l2 EPS8 signaling adaptor L2 involved_in ISO
IBA
IEA		 UniProtKB:Q08509|UniProtKB:Q8R5F8|UniProtKB:Q91WL0|UniProtKB:Q99K30 (PMID:14565974)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:14565974 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:205,875,825...205,901,109
Ensembl chr 1:196,446,287...196,471,541 		JBrowse link
G Eps8l3 EPS8 signaling adaptor L3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:198,202,862...198,216,255
Ensembl chr 2:195,514,692...195,528,085 		JBrowse link
G Fam98a family with sequence similarity 98, member A involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:27777970)		 UniProt
Ensembl
RGD		 PMID:27777970 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:19,874,082...19,888,744
Ensembl chr 6:19,874,071...19,888,742 		JBrowse link
G Hras HRas proto-oncogene, GTPase involved_in ISO (PMID:23027131) RGD PMID:23027131 NCBI chr 1:205,712,625...205,729,406
Ensembl chr 1:196,296,263...196,300,615 		JBrowse link
G Mtor mechanistic target of rapamycin kinase acts_upstream_of_or_within ISO (PMID:15467718) RGD PMID:15467718 NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Ndel1 nudE neurodevelopment protein 1-like 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:27777970)		 UniProt
Ensembl
RGD		 PMID:27777970 GO_REF:0000024 GO_REF:0000107 NCBI chr10:54,001,435...54,080,909
Ensembl chr10:53,516,491...53,570,907 		JBrowse link
G Nlgn1 neuroligin 1 involved_in IDA PMID:12930820 BHF-UCL PMID:12930820 RGD:8554754 NCBI chr 2:110,184,987...111,110,316
Ensembl chr 2:108,257,824...109,002,464 		JBrowse link
G P2ry12 purinergic receptor P2Y12 involved_in IMP PMID:17299767 ARUK-UCL PMID:17299767 RGD:13673751 NCBI chr 2:145,631,487...145,673,194
Ensembl chr 2:143,481,430...143,523,361 		JBrowse link
G Pfn1 profilin 1 involved_in ISO
IEA		 (PMID:23153535)
GO_REF:0000107		 RGD
Ensembl		 PMID:23153535 GO_REF:0000107 NCBI chr10:55,863,882...55,866,587
Ensembl chr10:55,365,262...55,527,631 		JBrowse link
G Plekhm1 pleckstrin homology and RUN domain containing M1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:27777970)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:27777970 GO_REF:0000024 GO_REF:0000107 NCBI chr10:88,313,837...88,366,182
Ensembl chr10:88,314,651...88,362,412 		JBrowse link
G Rac1 Rac family small GTPase 1 acts_upstream_of_or_within ISO (PMID:15467718) RGD PMID:15467718 NCBI chr12:16,150,411...16,170,864
Ensembl chr12:11,036,698...11,057,251 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20567
    regulation of biological process 13403
      regulation of cellular process 13038
        regulation of cellular component biogenesis 1154
          regulation of cell projection assembly 248
            regulation of plasma membrane bounded cell projection assembly 245
              regulation of ruffle assembly 33
                negative regulation of ruffle assembly 6
                positive regulation of ruffle assembly 17
Path 2
Term Annotations click to browse term
  biological_process 20567
    cellular process 19557
      cellular component organization or biogenesis 7115
        cellular component organization 6828
          cell projection organization 1889
            plasma membrane bounded cell projection organization 1849
              ruffle organization 58
                ruffle assembly 46
                  regulation of ruffle assembly 33
                    negative regulation of ruffle assembly 6
                    positive regulation of ruffle assembly 17
paths to the root