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Term:Knl1/Spc105 complex
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Accession:GO:0180019 term browser browse the term
Definition:A kinetochore subcomplex that binds to centromeric chromatin and forms part of the outer kinetochore. It helps to recruit outer kinetochore subunits that will bind to microtubules. In humans and yeast respectively, it consists of KNL1/Spc105p and ZWINT/Kre28p.

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Knl1/Spc105 complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Knl1 kinetochore scaffold 1 part_of ISO (PMID:27881301) RGD PMID:27881301 NCBI chr 3:106,029,627...106,091,915
Ensembl chr 3:106,029,661...106,091,915
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G Zwint ZW10 interacting kinetochore protein part_of ISO
PMID:27881301 GO_REF:0000024 NCBI chr20:15,938,157...15,953,997
Ensembl chr20:15,938,157...15,953,957
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Term paths to the root
Path 1
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  cellular_component 20106
    protein-containing complex 6459
      Knl1/Spc105 complex 2
Path 2
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  cellular_component 20106
    cellular anatomical entity 19949
      organelle 13336
        non-membrane-bounded organelle 5103
          intracellular non-membrane-bounded organelle 5102
            chromosome 1333
              chromosomal region 331
                chromosome, centromeric region 233
                  condensed chromosome, centromeric region 163
                    kinetochore 152
                      outer kinetochore 24
                        Knl1/Spc105 complex 2
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