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ONTOLOGY REPORT - ANNOTATIONS

Term:non-proteinogenic amino acid biosynthetic process
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Accession:GO:0170043 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of non-proteinogenic amino acids.
Synonyms:exact_synonym: non-proteinogenic amino acid anabolism;   non-proteinogenic amino acid formation;   non-proteinogenic amino acid synthesis;   non-proteinogenic biosynthesis


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beta-alanine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dpyd dihydropyrimidine dehydrogenase involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 2:206,609,043...207,474,982
Ensembl chr 2:206,609,122...207,474,982 		JBrowse link
G Upb1 beta-ureidopropionase 1 TAS RGD PMID:8449931 RGD:634224 NCBI chr20:13,217,252...13,243,590
Ensembl chr20:13,217,258...13,243,590 		JBrowse link
beta-alanine biosynthetic process via 3-ureidopropionate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Upb1 beta-ureidopropionase 1 involved_in ISO
IBA
ISS		 (PMID:22525402), (PMID:29976570)
GO_REF:0000033
GO_REF:0000024		 RGD
GO_Central
UniProt		 PMID:22525402 PMID:29976570 GO_REF:0000024 GO_REF:0000033 NCBI chr20:13,217,252...13,243,590
Ensembl chr20:13,217,258...13,243,590 		JBrowse link
citrulline biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 involved_in ISO (PMID:11092761), (PMID:26297558) RGD PMID:11092761 PMID:26297558 NCBI chr 1:239,375,657...239,407,956
Ensembl chr 1:239,375,669...239,407,890 		JBrowse link
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase involved_in IDA
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:7053379 GO_REF:0000033, RGD:10755426 NCBI chr 6:25,292,133...25,315,078
Ensembl chr 6:25,292,133...25,319,861 		JBrowse link
G Otc ornithine transcarbamylase involved_in IDA
ISO
IBA		 (PMID:2556444), (PMID:8112735)
GO_REF:0000033		 RGD
GO_Central		 PMID:2556444 PMID:8112735 PMID:9472964 GO_REF:0000033, RGD:4144071 NCBI chr  X:12,453,834...12,529,954
Ensembl chr  X:12,453,834...12,566,918 		JBrowse link
D-serine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Srr serine racemase involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:11054547), (PMID:15193426)
(PMID:10557334), (PMID:11054547), (PMID:12021263), (PMID:15710237)
GO_REF:0000033		 RGD
GO_Central		 PMID:10557334 PMID:11054547 PMID:12021263 PMID:15193426 PMID:15710237 GO_REF:0000033 NCBI chr10:59,769,563...59,786,688
Ensembl chr10:59,769,571...59,787,011 		JBrowse link
gamma-aminobutyric acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abat 4-aminobutyrate aminotransferase IMP RGD PMID:19540876 RGD:9588538 NCBI chr10:6,996,688...7,092,835
Ensembl chr10:6,999,819...7,092,835 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 involved_in ISO
ISS
IEA		 (MGI:5697738|PMID:26430123)
GO_REF:0000024
GO_REF:0000107
(PMID:26430123)		 RGD
UniProt
Ensembl		 PMID:26430123 GO_REF:0000024 GO_REF:0000107 MGI:5697738 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961 		JBrowse link
G Gad1 glutamate decarboxylase 1 involved_in IDA
ISO
IEA
IBA		 PMID:1924335
(MGI:892697|PMID:9177246)
GO_REF:0000107
(PMID:17384644)
GO_REF:0000033
(PMID:9177246)		 RGD
Ensembl
GO_Central		 PMID:9177246 PMID:17384644 PMID:17712632 PMID:1924335 GO_REF:0000033 GO_REF:0000107 MGI:892697, RGD:6480258, RGD:728511 NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333 		JBrowse link
G Gad2 glutamate decarboxylase 2 involved_in IDA
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:22108820 GO_REF:0000033, RGD:401900601 NCBI chr17:84,763,630...84,826,155
Ensembl chr17:84,763,628...84,826,155 		JBrowse link
G Slc1a3 solute carrier family 1 member 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1931872 (PMID:15305132)		 Ensembl
RGD		 PMID:15305132 GO_REF:0000107 NCBI chr 2:57,755,495...57,830,605
Ensembl chr 2:57,755,497...57,830,605 		JBrowse link
G Slc38a1 solute carrier family 38, member 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:32668809)
(MGI:6795362|PMID:32668809)		 UniProt
RGD		 PMID:32668809 GO_REF:0000024 MGI:6795362 NCBI chr 7:127,733,230...127,802,541
Ensembl chr 7:127,738,226...127,802,218 		JBrowse link
hydroxylysine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plod2 procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 involved_in ISO
IEA		 (PMID:10934207)
GO_REF:0000107		 RGD
Ensembl		 PMID:10934207 GO_REF:0000107 NCBI chr 8:93,084,548...93,167,255
Ensembl chr 8:93,084,513...93,167,255 		JBrowse link
G Plod3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 involved_in ISO
IEA		 (MGI:6202004|PMID:16447251)
(PMID:16447251)
GO_REF:0000107		 RGD
Ensembl		 PMID:16447251 GO_REF:0000107 MGI:6202004 NCBI chr12:19,676,384...19,686,945
Ensembl chr12:19,676,386...19,686,960 		JBrowse link
negative regulation of citrulline biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 involved_in ISO (PMID:19278978) RGD PMID:19278978 NCBI chr13:45,156,137...45,255,292
Ensembl chr13:45,156,146...45,255,246 		JBrowse link
ornithine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 involved_in ISO (PMID:11092761), (PMID:26297558) RGD PMID:11092761 PMID:26297558 NCBI chr 1:239,375,657...239,407,956
Ensembl chr 1:239,375,669...239,407,890 		JBrowse link
positive regulation of L-dopa biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Park7 Parkinsonism associated deglycase involved_in
acts_upstream_of		 IEA
ISO
ISS		 GO_REF:0000107
(PMID:16731528)
GO_REF:0000024		 Ensembl
RGD
ParkinsonsUK-UCL		 PMID:16731528 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20133
    cellular process 19325
      metabolic process 12307
        primary metabolic process 10934
          amino acid metabolic process 302
            non-proteinogenic amino acid metabolic process 78
              non-proteinogenic amino acid biosynthetic process 16
                1-aminocyclopropane-1-carboxylate biosynthetic process 0
                3-cyano-L-alanine biosynthetic process 0
                4-hydroxyproline biosynthetic process 0
                D-amino acid biosynthetic process + 1
                L-beta-ethynylserine biosynthetic process 0
                L-dopa biosynthetic process + 1
                L-proline betaine biosynthetic process 0
                L-propargylglycine biosynthetic process 0
                N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biosynthetic process 0
                beta-alanine biosynthetic process + 2
                citrulline biosynthetic process + 4
                discadenine biosynthetic process 0
                gamma-aminobutyric acid biosynthetic process 6
                homocysteine biosynthetic process + 0
                hydroxylysine biosynthetic process 2
                ornithine biosynthetic process 1
                phosphoarginine biosynthetic process 0
                sarcosine biosynthetic process 0
Path 2
Term Annotations click to browse term
  biological_process 20133
    cellular process 19325
      metabolic process 12307
        small molecule metabolic process 1905
          organic acid metabolic process 1034
            oxoacid metabolic process 1023
              carboxylic acid metabolic process 1008
                carboxylic acid biosynthetic process 326
                  non-proteinogenic amino acid biosynthetic process 16
                    1-aminocyclopropane-1-carboxylate biosynthetic process 0
                    3-cyano-L-alanine biosynthetic process 0
                    4-hydroxyproline biosynthetic process 0
                    D-amino acid biosynthetic process + 1
                    L-beta-ethynylserine biosynthetic process 0
                    L-dopa biosynthetic process + 1
                    L-proline betaine biosynthetic process 0
                    L-propargylglycine biosynthetic process 0
                    N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biosynthetic process 0
                    beta-alanine biosynthetic process + 2
                    citrulline biosynthetic process + 4
                    discadenine biosynthetic process 0
                    gamma-aminobutyric acid biosynthetic process 6
                    homocysteine biosynthetic process + 0
                    hydroxylysine biosynthetic process 2
                    ornithine biosynthetic process 1
                    phosphoarginine biosynthetic process 0
                    sarcosine biosynthetic process 0
paths to the root