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ONTOLOGY REPORT - ANNOTATIONS

Term:tRNA (guanine(26)-N2)-dimethyltransferase activity
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Accession:GO:0160104 term browser browse the term
Definition:Catalysis of the reaction:guanosine(26) in tRNA + 2 S-adenosyl-L-methionine = 2 H+ + N(2)-dimethylguanosine(26) in tRNA + 2 S-adenosyl-L-homocysteine.
Synonyms:exact_synonym: tRNA (guanine(26)-N(2))-dimethyltransferase activity;   tRNA (guanosine(26)-N(2))-dimethyltransferase activity;   tRNA (m(2)2G26)dimethyltransferase
 xref: EC:2.1.1.216;   RHEA:43140;   Reactome:R-HSA-6782416 "TRMT1 (hTRM1) dimethylates guanosine-26 of tRNA(Tyr)"


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tRNA (guanine(26)-N2)-dimethyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trmt1 tRNA methyltransferase 1 enables ISO (PMID:10982862) RGD PMID:10982862 NCBI chr19:23,456,756...23,471,581
Ensembl chr19:23,456,756...23,466,956 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21091
    catalytic activity 6174
      transferase activity 2443
        transferase activity, transferring one-carbon groups 214
          methyltransferase activity 203
            N-methyltransferase activity 100
              tRNA (guanine(26)-N2)-dimethyltransferase activity 1
Path 2
Term Annotations click to browse term
  molecular_function 21091
    catalytic activity 6174
      transferase activity 2443
        transferase activity, transferring one-carbon groups 214
          methyltransferase activity 203
            RNA methyltransferase activity 63
              tRNA methyltransferase activity 31
                tRNA (guanine) methyltransferase activity 12
                  tRNA (guanine(26)-N2)-dimethyltransferase activity 1
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