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ONTOLOGY REPORT - ANNOTATIONS

Term:non-canonical inflammasome complex
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Accession:GO:0160074 term browser browse the term
Definition:An inflammasome complex containing CASP4, known as caspase-11 (Casp11) in mouse, which assembles upon cytosolic lipopolysaccharide-binding and directly activates Gasdermin-D (GSDMD).


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non-canonical inflammasome complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp4 caspase 4 part_of ISO (PMID:25119034), (PMID:31268602)
(MGI:5510905|PMID:23887873), (MGI:6201935|PMID:30135078)		 RGD PMID:23887873 PMID:25119034 PMID:30135078 PMID:31268602 MGI:5510905 MGI:6201935 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20811
    protein-containing complex 6431
      non-canonical inflammasome complex 1
Path 2
Term Annotations click to browse term
  cellular_component 20811
    cellular anatomical entity 20571
      intracellular anatomical structure 15179
        cytoplasm 11872
          cytosol 4228
            non-canonical inflammasome complex 1
paths to the root