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ONTOLOGY REPORT - ANNOTATIONS

Term:transport across blood-brain barrier
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Accession:GO:0150104 term browser browse the term
Definition:The directed movement of substances (e.g. macromolecules, small molecules, ions) through the blood-brain barrier.
Synonyms:exact_synonym: transport across BBB
 only_in_taxon: NCBITaxon:6072 ! Eumetazoa


show annotations for term's descendants           Sort by:
transport across blood-brain barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor involved_in ISO
IEA		 (PMID:23973487)
GO_REF:0000107		 RGD
Ensembl		 PMID:23973487 GO_REF:0000107 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078 		JBrowse link
G Flvcr2 FLVCR choline and putative heme transporter 2 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 6:105,408,355...105,472,355
Ensembl chr 6:105,408,339...105,472,353 		JBrowse link
G Lrp1 LDL receptor related protein 1 involved_in ISO (MGI:5439721|PMID:20630619), (MGI:5754651|PMID:26619118) RGD PMID:20630619 PMID:26619118 MGI:5439721 MGI:5754651 NCBI chr 7:63,380,325...63,461,029
Ensembl chr 7:63,380,356...63,460,910 		JBrowse link
G Slc16a2 solute carrier family 16 member 2 involved_in ISO (PMID:28526555) RGD PMID:28526555 NCBI chr  X:68,725,365...68,848,572
Ensembl chr  X:68,723,261...68,848,771 		JBrowse link
G Slc1a5 solute carrier family 1 member 5 involved_in ISO (MGI:6393124|PMID:14622120) RGD PMID:14622120 MGI:6393124 NCBI chr 1:77,456,849...77,470,952
Ensembl chr 1:77,456,694...77,470,952 		JBrowse link
G Slc22a5 solute carrier family 22 member 5 involved_in ISO (MGI:6437032|PMID:14595704) RGD PMID:14595704 MGI:6437032 NCBI chr10:38,008,303...38,035,474
Ensembl chr10:38,008,311...38,035,309 		JBrowse link
G Slc2a1 solute carrier family 2 member 1 acts_upstream_of_or_within
involved_in		 ISO (PMID:1714544)
UniProtKB:P11169|UniProtKB:P13866 (PMID:23975336), (PMID:28993322)		 RGD PMID:1714544 PMID:23975336 PMID:28993322 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416 		JBrowse link
G Slc2a3 solute carrier family 2 member 3 involved_in ISO UniProtKB:P11166|UniProtKB:P13866 (PMID:23975336) RGD PMID:23975336 NCBI chr 4:155,960,944...156,026,000
Ensembl chr 4:155,960,946...156,025,472 		JBrowse link
G Slc5a1 solute carrier family 5 member 1 involved_in ISO UniProtKB:P11166|UniProtKB:P11169 (PMID:23975336) RGD PMID:23975336 NCBI chr14:77,553,990...77,618,589
Ensembl chr14:77,553,843...77,618,547 		JBrowse link
G Slc5a6 solute carrier family 5 member 6 involved_in ISO (PMID:25809983) RGD PMID:25809983 NCBI chr 6:25,319,187...25,331,713
Ensembl chr 6:25,320,442...25,331,712 		JBrowse link
lipid transport across blood-brain barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd36 CD36 molecule involved_in ISO
IEA		 (PMID:21395585)
GO_REF:0000107		 RGD
Ensembl		 PMID:21395585 GO_REF:0000107 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Fabp5 fatty acid binding protein 5 involved_in ISO (PMID:21395585) RGD PMID:21395585 NCBI chr 2:91,765,056...91,768,716
Ensembl chr 2:91,765,056...91,853,773 		JBrowse link
G Mfsd2a MFSD2 lysolipid transporter A, lysophospholipid involved_in ISO
IBA		 (PMID:26005865)
GO_REF:0000033
(MGI:5571501|PMID:24828044)		 RGD
GO_Central		 PMID:24828044 PMID:26005865 GO_REF:0000033 MGI:5571501 NCBI chr 5:135,225,801...135,240,744
Ensembl chr 5:135,225,816...135,240,690 		JBrowse link
G Slc27a1 solute carrier family 27 member 1 involved_in ISO
IEA		 (PMID:21395585)
GO_REF:0000107		 RGD
Ensembl		 PMID:21395585 GO_REF:0000107 NCBI chr16:18,278,984...18,300,173
Ensembl chr16:18,278,984...18,296,063 		JBrowse link
G Slc27a4 solute carrier family 27 member 4 involved_in ISO (PMID:21395585) RGD PMID:21395585 NCBI chr 3:13,075,022...13,087,943
Ensembl chr 3:13,075,022...13,087,943 		JBrowse link
negative regulation of lipid transport across blood-brain barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in ISO (PMID:24345162) RGD PMID:24345162 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
positive regulation of lipid transport across blood-brain barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in IEA
ISO		 GO_REF:0000107
(PMID:24345162)		 Ensembl
RGD		 PMID:24345162 GO_REF:0000107 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
xenobiotic transport across blood-brain barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A involved_in IMP
ISO		 (PMID:25986174)
(MGI:6369882|PMID:28587984)		 RGD PMID:25986174 PMID:28587984 PMID:25053619 MGI:6369882, RGD:11252095 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 involved_in ISO (PMID:25986174) RGD PMID:25986174 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 involved_in IMP
IGI		 PMID:12663688
PMID:17437408		 ARUK-UCL PMID:12663688 PMID:17437408 RGD:704399, RGD:14929203 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 involved_in IC
ISO		 PMID:15773906
(PMID:12958161)		 RGD PMID:12958161 PMID:15773906 RGD:14929200 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409 		JBrowse link
G Slc22a1 solute carrier family 22 member 1 involved_in NAS PMID:20477935 ARUK-UCL PMID:20477935 RGD:30309941 NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 involved_in NAS PMID:20477935 ARUK-UCL PMID:20477935 RGD:30309941 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20115
    localization 5683
      establishment of localization 4990
        transport 4683
          vascular transport 23
            transport across blood-brain barrier 22
              copper ion transport across blood-brain barrier 0
              lipid transport across blood-brain barrier + 6
              negative regulation of transport across blood-brain barrier + 1
              positive regulation of transport across blood-brain barrier + 1
              regulation of transport across blood-brain barrier + 1
              xenobiotic transport across blood-brain barrier 6
Path 2
Term Annotations click to browse term
  biological_process 20115
    multicellular organismal process 8852
      system process 3531
        circulatory system process 614
          vascular process in circulatory system 272
            vascular transport 23
              transport across blood-brain barrier 22
                copper ion transport across blood-brain barrier 0
                lipid transport across blood-brain barrier + 6
                negative regulation of transport across blood-brain barrier + 1
                positive regulation of transport across blood-brain barrier + 1
                regulation of transport across blood-brain barrier + 1
                xenobiotic transport across blood-brain barrier 6
paths to the root