ONTOLOGY REPORT - ANNOTATIONS
Term: amyloid-beta clearance by cellular catabolic process
Accession: GO:0150094
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Definition: The process in which amyloid-beta is removed from extracellular brain regions by cell surface receptor-mediated endocytosis, followed by intracellular degradation.
Synonyms: narrow_synonym: amyloid-beta clearance by phagocytosis
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Abca7
ATP binding cassette subfamily A member 7
involved_in
ISS ISO
GO_REF:0000024 (PMID:27472885)
UniProt RGD
PMID:27472885
GO_REF:0000024
NCBI chr 7:9,691,452...9,711,466
Ensembl chr 7:9,691,449...9,711,425
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Cd36
CD36 molecule
involved_in
ISO IMP IEA IBA
(PMID:18941241) GO_REF:0000107 GO_REF:0000033
RGD Ensembl GO_Central
PMID:18941241 PMID:18941241
GO_REF:0000033 GO_REF:0000107, RGD:13825436
NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
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Ide
insulin degrading enzyme
involved_in
IMP ISO IEA
PMID:18941241 (PMID:23525105) GO_REF:0000107
RGD Ensembl
PMID:23525105 PMID:18941241
GO_REF:0000107, RGD:13825436
NCBI chr 1:235,002,984...235,102,448
Ensembl chr 1:234,995,351...235,102,440
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Ldlr
low density lipoprotein receptor
involved_in
IEA ISO
GO_REF:0000107 (PMID:22383525)
Ensembl RGD
PMID:22383525
GO_REF:0000107
NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
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Lrp1
LDL receptor related protein 1
involved_in
ISO IEA IBA
(PMID:23152628), (PMID:24305823) GO_REF:0000107 GO_REF:0000033 UniProtKB:P05067|UniProtKB:P49768 (PMID:21289173), (PMID:23152628), (PMID:24305823)
RGD Ensembl GO_Central
PMID:21289173 PMID:23152628 PMID:24305823
GO_REF:0000033 GO_REF:0000107
NCBI chr 7:63,380,325...63,461,029
Ensembl chr 7:63,380,356...63,460,910
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Lrp4
LDL receptor related protein 4
involved_in
ISO
(PMID:18289866)
RGD
PMID:18289866
NCBI chr 3:77,429,600...77,483,593
Ensembl chr 3:77,429,798...77,483,593
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Mme
membrane metallo-endopeptidase
involved_in
ISO IMP IEA
UniProtKB:P05067 (PMID:15100223), (PMID:24825898) PMID:18941241 GO_REF:0000107
RGD Ensembl
PMID:15100223 PMID:24825898 PMID:18941241
GO_REF:0000107, RGD:13825436
NCBI chr 2:147,686,913...147,803,808
Ensembl chr 2:147,722,086...147,803,792
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Trem2
triggering receptor expressed on myeloid cells 2
involved_in
ISO
(PMID:33097708) (PMID:30617257), (PMID:31134514), (PMID:31980586)
RGD
PMID:30617257 PMID:31134514 PMID:31980586 PMID:33097708
NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170
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