ONTOLOGY REPORT - ANNOTATIONS
Term: amyloid-beta clearance by cellular catabolic process
Accession: GO:0150094
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Definition: The process in which amyloid-beta is removed from extracellular brain regions by cell surface receptor-mediated endocytosis, followed by intracellular degradation.
Synonyms: narrow_synonym: amyloid-beta clearance by phagocytosis
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ABCA7
ATP binding cassette subfamily A member 7
involved_in
ISO
(PMID:27472885)
UniProt
PMID:27472885
NCBI chr 2:77,357,161...77,375,349
Ensembl chr 2:77,357,218...77,375,180
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CD36
CD36 molecule
involved_in
IBA
GO_Central
GO_REF:0000033
NCBI chr 9:99,685,748...99,782,296
Ensembl chr 9:99,605,181...99,782,105
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IDE
insulin degrading enzyme
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr14:103,992,035...104,106,571
Ensembl chr14:103,992,039...104,106,576
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LDLR
low density lipoprotein receptor
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr 2:69,828,348...69,864,823
Ensembl chr 2:69,828,332...69,864,827
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LRP1
LDL receptor related protein 1
involved_in
ISO
(PMID:23152628), (PMID:24305823) (PMID:21289173) (PMID:24305823)
ARUK-UCL
PMID:21289173 PMID:23152628 PMID:24305823
NCBI chr 5:22,435,636...22,519,276
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LRP4
LDL receptor related protein 4
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr 2:15,616,137...15,672,876
Ensembl chr 2:15,616,131...15,672,874
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MME
membrane metalloendopeptidase
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr13:95,018,395...95,122,977
Ensembl chr13:95,019,081...95,126,045
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TREM2
triggering receptor expressed on myeloid cells 2
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr 7:36,465,921...36,471,509
Ensembl chr 7:36,465,324...36,471,516
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