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ONTOLOGY REPORT - ANNOTATIONS


Term:amyloid-beta clearance by cellular catabolic process
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Accession:GO:0150094 term browser browse the term
Definition:The process in which amyloid-beta is removed from extracellular brain regions by cell surface receptor-mediated endocytosis, followed by intracellular degradation.
Synonyms:narrow_synonym: amyloid-beta clearance by phagocytosis



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amyloid-beta clearance by cellular catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA7 ATP binding cassette subfamily A member 7 involved_in ISO (PMID:27472885) UniProt PMID:27472885 NCBI chr 2:77,357,161...77,375,349
Ensembl chr 2:77,357,218...77,375,180
JBrowse link
G CD36 CD36 molecule involved_in IBA GO_Central GO_REF:0000033 NCBI chr 9:99,685,748...99,782,296
Ensembl chr 9:99,605,181...99,782,105
JBrowse link
G IDE insulin degrading enzyme involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:103,992,035...104,106,571
Ensembl chr14:103,992,039...104,106,576
JBrowse link
G LDLR low density lipoprotein receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:69,828,348...69,864,823
Ensembl chr 2:69,828,332...69,864,827
JBrowse link
G LRP1 LDL receptor related protein 1 involved_in ISO (PMID:23152628), (PMID:24305823)
(PMID:21289173)
(PMID:24305823)
ARUK-UCL PMID:21289173 PMID:23152628 PMID:24305823 NCBI chr 5:22,435,636...22,519,276 JBrowse link
G LRP4 LDL receptor related protein 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:15,616,137...15,672,876
Ensembl chr 2:15,616,131...15,672,874
JBrowse link
G MME membrane metalloendopeptidase involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:95,018,395...95,122,977
Ensembl chr13:95,019,081...95,126,045
JBrowse link
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:36,465,921...36,471,509
Ensembl chr 7:36,465,324...36,471,516
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17668
    multicellular organismal process 8669
      amyloid-beta clearance 38
        amyloid-beta clearance by cellular catabolic process 8
Path 2
Term Annotations click to browse term
  biological_process 17668
    cellular process 17206
      metabolic process 10557
        amide metabolic process 443
          amyloid-beta metabolic process 69
            amyloid-beta clearance by cellular catabolic process 8
paths to the root