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ONTOLOGY REPORT - ANNOTATIONS

Term:amyloid-beta clearance by cellular catabolic process
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Accession:GO:0150094 term browser browse the term
Definition:The process in which amyloid-beta is removed from extracellular brain regions by cell surface receptor-mediated endocytosis, followed by intracellular degradation.
Synonyms:narrow_synonym: amyloid-beta clearance by phagocytosis


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amyloid-beta clearance by cellular catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca7 ATP-binding cassette, sub-family A member 7 involved_in IMP (PMID:27472885) UniProt PMID:27472885 NCBI chr10:79,832,328...79,851,406
Ensembl chr10:79,832,328...79,851,406 		JBrowse link
G Cd36 CD36 molecule involved_in IBA
ISO
IEA		 GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000119 NCBI chr 5:17,986,680...18,093,828
Ensembl chr 5:17,986,688...18,093,799 		JBrowse link
G Ide insulin degrading enzyme involved_in ISO GO_Central GO_REF:0000096 GO_REF:0000119 NCBI chr19:37,246,140...37,341,664
Ensembl chr19:37,246,142...37,340,010 		JBrowse link
G Ldlr low density lipoprotein receptor involved_in IDA (PMID:22383525) ARUK-UCL PMID:22383525 NCBI chr 9:21,634,872...21,661,215
Ensembl chr 9:21,634,779...21,661,215 		JBrowse link
G Lrp1 low density lipoprotein receptor-related protein 1 involved_in IBA
IMP
IEA
IDA
IGI
ISO		 (PMID:23152628)
(PMID:21289173)
(PMID:24305823)		 GO_Central
ARUK-UCL
Ensembl		 PMID:21289173 PMID:23152628 PMID:24305823 GO_REF:0000033 GO_REF:0000107 GO_REF:0000119 NCBI chr10:127,374,026...127,457,158
Ensembl chr10:127,374,030...127,457,017 		JBrowse link
G Lrp4 low density lipoprotein receptor-related protein 4 involved_in ISO
IEA		 GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr 2:91,287,794...91,344,246
Ensembl chr 2:91,287,856...91,344,124 		JBrowse link
G Mme membrane metallo endopeptidase involved_in ISO
IEA		 GO_Central
Ensembl		 GO_REF:0000096 GO_REF:0000107 GO_REF:0000119 NCBI chr 3:63,202,632...63,291,134
Ensembl chr 3:63,148,958...63,293,451 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISS
IMP
ISO		 (PMID:30617257), (PMID:31134514), (PMID:31980586) ARUK-UCL
GO_Central		 PMID:30617257 PMID:31134514 PMID:31980586 GO_REF:0000024 GO_REF:0000119 NCBI chr17:48,653,429...48,659,304
Ensembl chr17:48,653,429...48,661,175 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28635
    multicellular organismal process 9055
      amyloid-beta clearance 39
        amyloid-beta clearance by cellular catabolic process 8
Path 2
Term Annotations click to browse term
  biological_process 28635
    cellular process 18389
      metabolic process 11662
        amide metabolic process 505
          amyloid-beta metabolic process 80
            amyloid-beta clearance by cellular catabolic process 8
paths to the root