ONTOLOGY REPORT - ANNOTATIONS
Term: amyloid-beta clearance by cellular catabolic process
Accession: GO:0150094
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Definition: The process in which amyloid-beta is removed from extracellular brain regions by cell surface receptor-mediated endocytosis, followed by intracellular degradation.
Synonyms: narrow_synonym: amyloid-beta clearance by phagocytosis
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ABCA7
ATP binding cassette subfamily A member 7
involved_in
ISS
UniProt
GO_REF:0000024
NCBI chr19:1,040,107...1,065,572
Ensembl chr19:1,039,997...1,065,572
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CD36
CD36 molecule (CD36 blood group)
involved_in
IMP IBA
(PMID:18941241)
ARUK-UCL GO_Central
PMID:18941241
GO_REF:0000033
NCBI chr 7:80,602,207...80,679,274
Ensembl chr 7:80,369,575...80,679,277
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IDE
insulin degrading enzyme
involved_in
ISS IMP
(PMID:23525105)
ARUK-UCL
PMID:23525105
GO_REF:0000024
NCBI chr10:92,451,684...92,574,093
Ensembl chr10:92,451,684...92,574,096
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LDLR
low density lipoprotein receptor
involved_in
ISS IEA
ARUK-UCL Ensembl
GO_REF:0000024 GO_REF:0000107
NCBI chr19:11,089,463...11,133,820
Ensembl chr19:11,089,418...11,133,820
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LRP1
LDL receptor related protein 1
involved_in
ISS IBA IMP
(PMID:23152628), (PMID:24305823)
ARUK-UCL GO_Central
PMID:23152628 PMID:24305823
GO_REF:0000024 GO_REF:0000033
NCBI chr12:57,128,483...57,213,361
Ensembl chr12:57,128,483...57,213,361
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LRP4
LDL receptor related protein 4
involved_in
IMP
(PMID:18289866)
ARUK-UCL
PMID:18289866
NCBI chr11:46,856,717...46,918,550
Ensembl chr11:46,856,717...46,918,642
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MME
membrane metalloendopeptidase
involved_in
ISS IGI IDA IEA
(PMID:24825898) (PMID:15100223)
ARUK-UCL Ensembl
PMID:15100223 PMID:24825898
GO_REF:0000024 GO_REF:0000107
NCBI chr 3:155,024,202...155,183,729
Ensembl chr 3:155,024,124...155,183,704
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TREM2
triggering receptor expressed on myeloid cells 2
involved_in
ISS IMP IEA
(PMID:33097708)
ARUK-UCL Ensembl
PMID:33097708
GO_REF:0000024 GO_REF:0000107
NCBI chr 6:41,158,508...41,163,116
Ensembl chr 6:41,158,506...41,163,186
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