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ONTOLOGY REPORT - ANNOTATIONS

Term:amyloid-beta clearance by cellular catabolic process
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Accession:GO:0150094 term browser browse the term
Definition:The process in which amyloid-beta is removed from extracellular brain regions by cell surface receptor-mediated endocytosis, followed by intracellular degradation.
Synonyms:narrow_synonym: amyloid-beta clearance by phagocytosis

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amyloid-beta clearance by cellular catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca7 ATP binding cassette subfamily A member 7 involved_in ISO (PMID:27472885) UniProt PMID:27472885 NCBI chrNW_004955495:6,818,002...6,838,177
Ensembl chrNW_004955495:6,815,562...6,836,772 		JBrowse link
G Cd36 CD36 molecule (CD36 blood group) involved_in ISO (PMID:18941241) ARUK-UCL PMID:18941241 RGD:13825436 NCBI chrNW_004955410:5,003,720...5,120,903
Ensembl chrNW_004955410:5,003,668...5,075,313 		JBrowse link
G Ide insulin degrading enzyme involved_in ISO (PMID:23525105)
PMID:18941241		 ARUK-UCL PMID:18941241 PMID:23525105 RGD:13825436 NCBI chrNW_004955425:819,461...926,440
Ensembl chrNW_004955425:847,615...926,318 		JBrowse link
G Ldlr low density lipoprotein receptor involved_in ISO (PMID:22383525) ARUK-UCL PMID:22383525 NCBI chrNW_004955495:2,114,702...2,135,584
Ensembl chrNW_004955495:2,114,434...2,138,056 		JBrowse link
G Lrp1 LDL receptor related protein 1 involved_in ISO (PMID:23152628), (PMID:24305823)
(PMID:24305823)
(PMID:21289173)		 ARUK-UCL PMID:21289173 PMID:23152628 PMID:24305823 NCBI chrNW_004955458:4,861,431...4,941,939
Ensembl chrNW_004955458:4,861,431...4,941,146 		JBrowse link
G Lrp4 LDL receptor related protein 4 involved_in ISO (PMID:18289866) ARUK-UCL PMID:18289866 NCBI chrNW_004955422:1,191,338...1,238,227
Ensembl chrNW_004955422:1,191,338...1,238,227 		JBrowse link
G Mme membrane metalloendopeptidase involved_in ISO (PMID:15100223)
PMID:18941241
(PMID:24825898)		 ARUK-UCL PMID:15100223 PMID:18941241 PMID:24825898 RGD:13825436 NCBI chrNW_004955448:6,193,113...6,311,666
Ensembl chrNW_004955448:6,226,059...6,314,949 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:33097708)
(PMID:30617257), (PMID:31134514), (PMID:31980586)		 ARUK-UCL PMID:30617257 PMID:31134514 PMID:31980586 PMID:33097708 NCBI chrNW_004955437:7,780,886...7,785,597
Ensembl chrNW_004955437:7,780,679...7,785,697 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12572
    multicellular organismal process 6259
      amyloid-beta clearance 39
        amyloid-beta clearance by cellular catabolic process 8
Path 2
Term Annotations click to browse term
  biological_process 12572
    cellular process 12010
      metabolic process 7974
        amide metabolic process 355
          amyloid-beta metabolic process 56
            amyloid-beta clearance by cellular catabolic process 8
paths to the root