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ONTOLOGY REPORT - ANNOTATIONS


Term:amyloid-beta clearance by cellular catabolic process
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Accession:GO:0150094 term browser browse the term
Definition:The process in which amyloid-beta is removed from extracellular brain regions by cell surface receptor-mediated endocytosis, followed by intracellular degradation.
Synonyms:narrow_synonym: amyloid-beta clearance by phagocytosis



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amyloid-beta clearance by cellular catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca7 ATP binding cassette subfamily A member 7 involved_in ISS
ISO
GO_REF:0000024
(MGI:6271506|PMID:27472885)
UniProt
RGD
PMID:27472885 GO_REF:0000024 MGI:6271506 NCBI chr 7:9,691,452...9,711,466
Ensembl chr 7:9,691,449...9,711,425
JBrowse link
G Cd36 CD36 molecule involved_in IBA
IMP
ISO
PMID:21873635
PMID:18941241
(PMID:18941241)
RGD PMID:18941241 PMID:21873635 PMID:18941241 RGD:13792537, RGD:13825436 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
JBrowse link
G Ide insulin degrading enzyme involved_in IMP
ISO
PMID:18941241
(PMID:23525105)
RGD PMID:23525105 PMID:18941241 RGD:13825436 NCBI chr 1:235,002,984...235,102,448
Ensembl chr 1:234,995,351...235,102,440
JBrowse link
G Ldlr low density lipoprotein receptor involved_in ISO (MGI:5902678|PMID:22383525) RGD PMID:22383525 MGI:5902678 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G LOC120093085 platelet glycoprotein 4-like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:17,487,837...17,514,900 JBrowse link
G Lrp1 LDL receptor related protein 1 involved_in ISO
IBA
(PMID:23152628), (PMID:24305823)
PMID:21873635
UniProtKB:P05067|UniProtKB:P49768 (MGI:5465209|PMID:23152628), (MGI:5529723|PMID:24305823), (MGI:5897551|PMID:21289173)
RGD PMID:21289173 PMID:23152628 PMID:24305823 PMID:21873635 MGI:5465209 MGI:5529723 MGI:5897551, RGD:13792537 NCBI chr 7:63,380,325...63,461,029
Ensembl chr 7:63,380,356...63,460,910
JBrowse link
G Lrp4 LDL receptor related protein 4 involved_in ISO (PMID:18289866) RGD PMID:18289866 NCBI chr 3:77,429,600...77,483,593
Ensembl chr 3:77,429,798...77,483,593
JBrowse link
G Mme membrane metallo-endopeptidase involved_in ISO
IEA
IMP
UniProtKB:P05067 (PMID:15100223), (PMID:24825898)
GO_REF:0000107
PMID:18941241
RGD
Ensembl
PMID:15100223 PMID:24825898 PMID:18941241 GO_REF:0000107, RGD:13825436 NCBI chr 2:147,686,913...147,803,808
Ensembl chr 2:147,722,086...147,803,792
JBrowse link
G RGD1565355 similar to fatty acid translocase/CD36 involved_in IBA
IEA
PMID:21873635
GO_REF:0000107
Ensembl PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 4:17,424,749...17,465,808
Ensembl chr 4:17,354,466...17,513,903
JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:33097708)
(MGI:6313424|PMID:30617257), (MGI:6393391|PMID:31980586), (MGI:6695864|PMID:31134514)
RGD PMID:30617257 PMID:31134514 PMID:31980586 PMID:33097708 MGI:6313424 MGI:6393391 MGI:6695864 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19512
    multicellular organismal process 9052
      amyloid-beta clearance 39
        amyloid-beta clearance by cellular catabolic process 10
Path 2
Term Annotations click to browse term
  biological_process 19512
    metabolic process 11791
      catabolic process 2552
        cellular catabolic process 2174
          amyloid-beta clearance by cellular catabolic process 10
paths to the root