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ONTOLOGY REPORT - ANNOTATIONS

Term:amyloid-beta clearance by transcytosis
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Accession:GO:0150093 term browser browse the term
Definition:The process in which amyloid-beta is removed from extracellular brain regions by cell surface receptor-mediated endocytosis, followed by transcytosis across the blood-brain barrier.


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amyloid-beta clearance by transcytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLTC clathrin heavy chain involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:35,848,894...35,926,028
Ensembl chr12:35,848,540...35,926,015 		JBrowse link
G LRP1 LDL receptor related protein 1 involved_in ISO (PMID:26005850)
(PMID:20630619)		 ARUK-UCL PMID:20630619 PMID:26005850 NCBI chr 5:22,435,636...22,519,276 JBrowse link
G LRPAP1 LDL receptor related protein associated protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:2,129,492...2,145,632
Ensembl chr 8:2,125,405...2,145,647 		JBrowse link
G PICALM phosphatidylinositol binding clathrin assembly protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:19,835,934...19,947,239
Ensembl chr 9:19,835,938...20,123,566 		JBrowse link
G RAB11A RAB11A, member RAS oncogene family involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:163,858,254...163,887,741
Ensembl chr 1:163,858,123...163,891,527 		JBrowse link
G RAB11B RAB11B, member RAS oncogene family involved_in ISO (PMID:26005850) ARUK-UCL PMID:26005850 NCBI chr 2:70,884,457...70,896,169
Ensembl chr 2:70,884,462...70,896,172 		JBrowse link
G RAB5A RAB5A, member RAS oncogene family involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:6,905,302...6,940,165
Ensembl chr13:6,905,390...6,941,423 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18933
    multicellular organismal process 8739
      transcytosis 26
        amyloid-beta clearance by transcytosis 7
Path 2
Term Annotations click to browse term
  biological_process 18933
    localization 5401
      establishment of localization 4745
        transport 4429
          vesicle-mediated transport 1558
            transcytosis 26
              amyloid-beta clearance by transcytosis 7
paths to the root