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ONTOLOGY REPORT - ANNOTATIONS

Term:amyloid-beta clearance by transcytosis
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Accession:GO:0150093 term browser browse the term
Definition:The process in which amyloid-beta is removed from extracellular brain regions by cell surface receptor-mediated endocytosis, followed by transcytosis across the blood-brain barrier.

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amyloid-beta clearance by transcytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cltc clathrin heavy chain involved_in ISO (PMID:26005850) ARUK-UCL PMID:26005850 NCBI chrNW_004624871:1,439,975...1,507,514
Ensembl chrNW_004624871:1,439,838...1,510,911 		JBrowse link
G Lrp1 LDL receptor related protein 1 involved_in ISO (PMID:20630619)
(PMID:26005850)		 ARUK-UCL PMID:20630619 PMID:26005850 NCBI chrNW_004624802:10,734,907...10,812,888
Ensembl chrNW_004624802:10,734,263...10,812,763 		JBrowse link
G Lrpap1 LDL receptor related protein associated protein 1 involved_in ISO (PMID:26005850) ARUK-UCL PMID:26005850 NCBI chrNW_004624755:24,436,128...24,447,923
Ensembl chrNW_004624755:24,436,208...24,449,147 		JBrowse link
G Picalm phosphatidylinositol binding clathrin assembly protein involved_in ISO (PMID:26005850) ARUK-UCL PMID:26005850 NCBI chrNW_004624845:3,875,601...3,990,347
Ensembl chrNW_004624845:3,891,061...3,990,342 		JBrowse link
G Rab11a RAB11A, member RAS oncogene family involved_in ISO (PMID:26005850) ARUK-UCL PMID:26005850 NCBI chrNW_004624781:6,699,926...6,718,020
Ensembl chrNW_004624781:6,699,926...6,718,545 		JBrowse link
G Rab11b RAB11B, member RAS oncogene family involved_in ISO (PMID:26005850) ARUK-UCL PMID:26005850 NCBI chrNW_004624828:1,165,877...1,174,306
Ensembl chrNW_004624828:1,165,327...1,174,417 		JBrowse link
G Rab5a RAB5A, member RAS oncogene family involved_in ISO (PMID:26005850) ARUK-UCL PMID:26005850 NCBI chrNW_004624821:5,271,246...5,311,469 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17640
    multicellular organismal process 7677
      transcytosis 25
        amyloid-beta clearance by transcytosis 7
Path 2
Term Annotations click to browse term
  biological_process 17640
    localization 5189
      establishment of localization 4552
        transport 4227
          vesicle-mediated transport 1488
            transcytosis 25
              amyloid-beta clearance by transcytosis 7
paths to the root