ONTOLOGY REPORT - ANNOTATIONS
Term: amyloid-beta clearance by transcytosis
Accession: GO:0150093
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Definition: The process in which amyloid-beta is removed from extracellular brain regions by cell surface receptor-mediated endocytosis, followed by transcytosis across the blood-brain barrier.
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Cltc
clathrin heavy chain
involved_in
ISO
GO_Central
GO_REF:0000119
NCBI chr11:86,585,178...86,648,637
Ensembl chr11:86,585,177...86,648,391
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Lrp1
low density lipoprotein receptor-related protein 1
involved_in
ISO IEA IDA IBA
(PMID:20630619)
GO_Central Ensembl ARUK-UCL
PMID:20630619
GO_REF:0000033 GO_REF:0000107 GO_REF:0000119
NCBI chr10:127,374,026...127,457,158
Ensembl chr10:127,374,030...127,457,017
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Lrpap1
low density lipoprotein receptor-related protein associated protein 1
involved_in
IEA ISO
Ensembl GO_Central
GO_REF:0000107 GO_REF:0000119
NCBI chr 5:35,248,834...35,263,043
Ensembl chr 5:35,248,845...35,263,110
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Picalm
phosphatidylinositol binding clathrin assembly protein
involved_in
ISO IMP IGI
(PMID:26005850)
GO_Central ARUK-UCL
PMID:26005850
GO_REF:0000119
NCBI chr 7:89,778,711...89,858,655
Ensembl chr 7:89,779,421...89,862,673
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Rab11a
RAB11A, member RAS oncogene family
involved_in
IEA ISO
Ensembl GO_Central
GO_REF:0000107 GO_REF:0000119
NCBI chr 9:64,622,582...64,645,038
Ensembl chr 9:64,622,581...64,645,040
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Rab11b
RAB11B, member RAS oncogene family
involved_in
ISO IEA
GO_Central Ensembl
GO_REF:0000107 GO_REF:0000119
NCBI chr17:33,961,458...33,979,460
Ensembl chr17:33,961,458...33,979,504
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Rab5a
RAB5A, member RAS oncogene family
involved_in
IEA ISO
Ensembl GO_Central
GO_REF:0000107 GO_REF:0000119
NCBI chr17:53,786,262...53,814,706
Ensembl chr17:53,786,262...53,814,708
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