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ONTOLOGY REPORT - ANNOTATIONS

Term:amyloid-beta clearance by transcytosis
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Accession:GO:0150093 term browser browse the term
Definition:The process in which amyloid-beta is removed from extracellular brain regions by cell surface receptor-mediated endocytosis, followed by transcytosis across the blood-brain barrier.


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amyloid-beta clearance by transcytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLTC clathrin heavy chain involved_in IMP (PMID:26005850) ARUK-UCL PMID:26005850 NCBI chr17:59,619,895...59,696,956
Ensembl chr17:59,619,680...59,696,956 		JBrowse link
G LRP1 LDL receptor related protein 1 involved_in ISS
IBA
IGI		 (PMID:26005850) ARUK-UCL
GO_Central		 PMID:26005850 GO_REF:0000024 GO_REF:0000033 NCBI chr12:57,128,483...57,213,361
Ensembl chr12:57,128,483...57,213,361 		JBrowse link
G LRPAP1 LDL receptor related protein associated protein 1 involved_in IMP (PMID:26005850) ARUK-UCL PMID:26005850 NCBI chr 4:3,503,612...3,532,422
Ensembl chr 4:3,503,612...3,532,446 		JBrowse link
G PICALM phosphatidylinositol binding clathrin assembly protein involved_in IGI
IEA
ISS		 (PMID:26005850) ARUK-UCL
Ensembl		 PMID:26005850 GO_REF:0000107 NCBI chr11:85,957,175...86,069,860
Ensembl chr11:85,957,175...86,069,882 		JBrowse link
G RAB11A RAB11A, member RAS oncogene family involved_in IGI (PMID:26005850) ARUK-UCL PMID:26005850 NCBI chr15:65,869,491...65,891,989
Ensembl chr15:65,726,054...65,891,989 		JBrowse link
G RAB11B RAB11B, member RAS oncogene family involved_in IGI (PMID:26005850) ARUK-UCL PMID:26005850 NCBI chr19:8,390,360...8,404,434
Ensembl chr19:8,389,981...8,404,434 		JBrowse link
G RAB5A RAB5A, member RAS oncogene family involved_in IGI (PMID:26005850) ARUK-UCL PMID:26005850 NCBI chr 3:19,947,097...19,985,175
Ensembl chr 3:19,947,097...19,985,175 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20486
    multicellular organismal process 8545
      transcytosis 27
        amyloid-beta clearance by transcytosis 7
Path 2
Term Annotations click to browse term
  biological_process 20486
    localization 5974
      establishment of localization 5308
        transport 4885
          vesicle-mediated transport 1741
            transcytosis 27
              amyloid-beta clearance by transcytosis 7
paths to the root