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ONTOLOGY REPORT - ANNOTATIONS


Term:amyloid-beta clearance by transcytosis
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Accession:GO:0150093 term browser browse the term
Definition:The process in which amyloid-beta is removed from extracellular brain regions by cell surface receptor-mediated endocytosis, followed by transcytosis across the blood-brain barrier.



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amyloid-beta clearance by transcytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLTC clathrin heavy chain involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:34,116,344...34,183,023
Ensembl chr 9:34,116,634...34,182,719
JBrowse link
G LRP1 LDL receptor related protein 1 involved_in IEA
IBA
Ensembl
GO_Central
GO_REF:0000033 GO_REF:0000107 NCBI chr10:1,260,256...1,341,705
Ensembl chr10:1,260,719...1,352,271
JBrowse link
G LRP6 LDL receptor related protein 6 involved_in IBA GO_Central GO_REF:0000033 NCBI chr27:34,003,334...34,166,334
Ensembl chr27:34,003,539...34,161,437
JBrowse link
G LRPAP1 LDL receptor related protein associated protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:60,840,804...60,852,821
Ensembl chr 3:60,840,882...60,901,258
JBrowse link
G PICALM phosphatidylinositol binding clathrin assembly protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:13,437,819...13,540,167
Ensembl chr21:13,437,925...13,539,616
JBrowse link
G RAB11A RAB11A, member RAS oncogene family involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:30,200,831...30,218,412
Ensembl chr30:30,200,831...30,218,411
JBrowse link
G RAB11B RAB11B, member RAS oncogene family involved_in ISO (PMID:26005850) ARUK-UCL PMID:26005850 NCBI chr20:52,955,949...52,966,279
Ensembl chr20:52,956,529...52,965,383
JBrowse link
G RAB5A RAB5A, member RAS oncogene family involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:23,303,650...23,333,571
Ensembl chr23:23,304,940...23,332,206
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 22103
    multicellular organismal process 8173
      transcytosis 27
        amyloid-beta clearance by transcytosis 8
Path 2
Term Annotations click to browse term
  biological_process 22103
    localization 5633
      establishment of localization 4969
        transport 4610
          vesicle-mediated transport 1617
            transcytosis 27
              amyloid-beta clearance by transcytosis 8
paths to the root