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ONTOLOGY REPORT - ANNOTATIONS

Term:amyloid-beta clearance by transcytosis
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Accession:GO:0150093 term browser browse the term
Definition:The process in which amyloid-beta is removed from extracellular brain regions by cell surface receptor-mediated endocytosis, followed by transcytosis across the blood-brain barrier.

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amyloid-beta clearance by transcytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cltc clathrin heavy chain involved_in ISO (PMID:26005850) ARUK-UCL PMID:26005850 NCBI chrNW_004955451:3,380,304...3,445,973
Ensembl chrNW_004955451:3,380,304...3,445,973 		JBrowse link
G Lrp1 LDL receptor related protein 1 involved_in ISO (PMID:20630619)
(PMID:26005850)		 ARUK-UCL PMID:20630619 PMID:26005850 NCBI chrNW_004955458:4,861,431...4,941,939
Ensembl chrNW_004955458:4,861,431...4,941,146 		JBrowse link
G Lrpap1 LDL receptor related protein associated protein 1 involved_in ISO (PMID:26005850) ARUK-UCL PMID:26005850 NCBI chrNW_004955514:2,195,228...2,208,258
Ensembl chrNW_004955514:2,195,228...2,208,688 		JBrowse link
G Picalm phosphatidylinositol binding clathrin assembly protein involved_in ISO (PMID:26005850) ARUK-UCL PMID:26005850 NCBI chrNW_004955414:6,871,220...6,970,569
Ensembl chrNW_004955414:6,871,520...6,969,208 		JBrowse link
G Rab11a RAB11A, member RAS oncogene family involved_in ISO (PMID:26005850) ARUK-UCL PMID:26005850 NCBI chrNW_004955450:9,638,761...9,656,291
Ensembl chrNW_004955450:9,638,761...9,656,603 		JBrowse link
G Rab11b RAB11B, member RAS oncogene family involved_in ISO (PMID:26005850) ARUK-UCL PMID:26005850 NCBI chrNW_004955563:1,008,267...1,017,315
Ensembl chrNW_004955563:1,008,769...1,017,315 		JBrowse link
G Rab5a RAB5A, member RAS oncogene family involved_in ISO (PMID:26005850) ARUK-UCL PMID:26005850 NCBI chrNW_004955430:11,991,548...12,040,003 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12563
    multicellular organismal process 6265
      transcytosis 26
        amyloid-beta clearance by transcytosis 7
Path 2
Term Annotations click to browse term
  biological_process 12563
    localization 4337
      establishment of localization 3699
        transport 3430
          vesicle-mediated transport 1240
            transcytosis 26
              amyloid-beta clearance by transcytosis 7
paths to the root