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ONTOLOGY REPORT - ANNOTATIONS

Term:NAD-dependent protein lysine deacylase activity
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Accession:GO:0141218 term browser browse the term
Definition:Removal of an acyl group from a protein via transfer of the acyl group to NAD+, producing nicotinamide.
Synonyms:broad_synonym: protein lysine deacylase activity


show annotations for term's descendants           Sort by:
histone deacetylase activity, NAD-dependent term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sirt1 sirtuin 1 enables IDA
ISO
IBA		 (PMID:10693811)
GO_REF:0000033
(PMID:12006491), (PMID:15469825), (PMID:16079181), (PMID:16959573), (PMID:28497810)		 RGD
GO_Central		 PMID:10693811 PMID:12006491 PMID:15469825 PMID:16079181 PMID:16959573 More... GO_REF:0000033, RGD:2316170 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Sirt2 sirtuin 2 NOT|enables ISO
IBA
IEA		 (PMID:24177535)
GO_REF:0000033
GO_REF:0000002
(PMID:11427894), (PMID:12697818)		 RGD
GO_Central
InterPro		 PMID:11427894 PMID:12697818 PMID:24177535 GO_REF:0000002 GO_REF:0000033 NCBI chr 1:84,053,883...84,076,975
Ensembl chr 1:84,052,903...84,076,975 		JBrowse link
G Sirt3 sirtuin 3 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:195,942,066...195,964,472
Ensembl chr 1:195,942,073...195,964,808 		JBrowse link
G Sirt6 sirtuin 6 enables ISO (PMID:24043303), (PMID:27912097) RGD PMID:24043303 PMID:27912097 NCBI chr 7:8,082,312...8,087,776
Ensembl chr 7:8,082,364...8,098,914 		JBrowse link
histone H3K14 deacetylase activity, NAD-dependent term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sirt1 sirtuin 1 enables ISO
IEA		 (PMID:15469825)
GO_REF:0000107		 RGD
Ensembl		 PMID:15469825 GO_REF:0000107 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Sirt2 sirtuin 2 enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr 1:84,053,883...84,076,975
Ensembl chr 1:84,052,903...84,076,975 		JBrowse link
G Sirt7 sirtuin 7 enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr10:105,896,476...105,903,301
Ensembl chr10:105,896,476...105,903,172 		JBrowse link
histone H3K18 deacetylase activity, NAD-dependent term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sirt1 sirtuin 1 enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Sirt2 sirtuin 2 enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr 1:84,053,883...84,076,975
Ensembl chr 1:84,052,903...84,076,975 		JBrowse link
G Sirt6 sirtuin 6 enables ISO (PMID:27043296)
(PMID:31002797)		 RGD PMID:27043296 PMID:31002797 NCBI chr 7:8,082,312...8,087,776
Ensembl chr 7:8,082,364...8,098,914 		JBrowse link
G Sirt7 sirtuin 7 enables ISS
ISO
IBA		 GO_REF:0000024
(PMID:27225932), (PMID:31226208), (PMID:31256246)
GO_REF:0000033
(PMID:22722849), (PMID:26907567), (PMID:28655758), (PMID:30420520), (PMID:30653310), (PMID:35939806)		 UniProt
RGD
GO_Central		 PMID:22722849 PMID:26907567 PMID:27225932 PMID:28655758 PMID:30420520 More... GO_REF:0000024 GO_REF:0000033 NCBI chr10:105,896,476...105,903,301
Ensembl chr10:105,896,476...105,903,172 		JBrowse link
histone H3K4 deacetylase activity, NAD-dependent term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sirt1 sirtuin 1 enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Sirt2 sirtuin 2 enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr 1:84,053,883...84,076,975
Ensembl chr 1:84,052,903...84,076,975 		JBrowse link
G Sirt7 sirtuin 7 enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr10:105,896,476...105,903,301
Ensembl chr10:105,896,476...105,903,172 		JBrowse link
histone H3K56 deacetylase activity, NAD-dependent term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sirt1 sirtuin 1 enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Sirt2 sirtuin 2 enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr 1:84,053,883...84,076,975
Ensembl chr 1:84,052,903...84,076,975 		JBrowse link
G Sirt6 sirtuin 6 enables ISO (PMID:23911928), (PMID:26456828), (PMID:26898756), (PMID:27912097), (PMID:30374165)
(PMID:21098266), (PMID:25915124), (PMID:28355567), (PMID:31002797), (PMID:31399344)		 RGD PMID:21098266 PMID:23911928 PMID:25915124 PMID:26456828 PMID:26898756 More... NCBI chr 7:8,082,312...8,087,776
Ensembl chr 7:8,082,364...8,098,914 		JBrowse link
G Sirt7 sirtuin 7 enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr10:105,896,476...105,903,301
Ensembl chr10:105,896,476...105,903,172 		JBrowse link
histone H3K9 deacetylase activity, NAD-dependent term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sirt1 sirtuin 1 enables IEA
ISO		 GO_REF:0000107
(PMID:20972425)
(PMID:15469825)		 Ensembl
RGD		 PMID:15469825 PMID:20972425 GO_REF:0000107 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Sirt2 sirtuin 2 enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr 1:84,053,883...84,076,975
Ensembl chr 1:84,052,903...84,076,975 		JBrowse link
G Sirt6 sirtuin 6 enables ISO
IBA		 (PMID:18337721), (PMID:23892288), (PMID:26456828), (PMID:29555651), (PMID:30374165), (PMID:33067423)
(PMID:20141841), (PMID:21098266), (PMID:25915124), (PMID:28355567), (PMID:29555651), (PMID:31002797), (PMID:31399344)
GO_REF:0000033		 RGD
GO_Central		 PMID:18337721 PMID:20141841 PMID:21098266 PMID:23892288 PMID:25915124 More... GO_REF:0000033 NCBI chr 7:8,082,312...8,087,776
Ensembl chr 7:8,082,364...8,098,914 		JBrowse link
G Sirt7 sirtuin 7 enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr10:105,896,476...105,903,301
Ensembl chr10:105,896,476...105,903,172 		JBrowse link
histone H4K16 deacetylase activity, NAD-dependent term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sirt1 sirtuin 1 enables ISO
IEA		 (PMID:15469825)
GO_REF:0000107		 RGD
Ensembl		 PMID:15469825 GO_REF:0000107 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Sirt2 sirtuin 2 enables ISO
IEA
ISS		 (PMID:16648462)
GO_REF:0000003
GO_REF:0000107
GO_REF:0000024		 RGD
UniProt
Ensembl		 PMID:16648462 GO_REF:0000003 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:84,053,883...84,076,975
Ensembl chr 1:84,052,903...84,076,975 		JBrowse link
G Sirt7 sirtuin 7 enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr10:105,896,476...105,903,301
Ensembl chr10:105,896,476...105,903,172 		JBrowse link
NAD-dependent protein lysine deacetylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sirt1 sirtuin 1 enables ISO (PMID:30409912)
(PMID:11250901), (PMID:11672523), (PMID:15220471), (PMID:15716268), (PMID:16790548)
(PMID:11672523), (PMID:15692560), (PMID:20100829), (PMID:20955178), (PMID:21775285), (PMID:22918831), (PMID:23142079), (PMID:29681526), (PMID:29765047), (PMID:30193097), (PMID:32034146), (PMID:32538779)		 RGD PMID:11250901 PMID:11672523 PMID:15220471 PMID:15692560 PMID:15716268 More... NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Sirt2 sirtuin 2 enables ISS
ISO
IDA		 GO_REF:0000024
(PMID:34059674)
(PMID:18722353), (PMID:21949390), (PMID:23932781), (PMID:24681946)
PMID:17344398		 UniProt
RGD		 PMID:18722353 PMID:21949390 PMID:23932781 PMID:24681946 PMID:34059674 More... GO_REF:0000024, RGD:8553877 NCBI chr 1:84,053,883...84,076,975
Ensembl chr 1:84,052,903...84,076,975 		JBrowse link
G Sirt3 sirtuin 3 enables ISO (PMID:16790548), (PMID:26620563)
(PMID:25023514)		 RGD PMID:16790548 PMID:25023514 PMID:26620563 NCBI chr 1:195,942,066...195,964,472
Ensembl chr 1:195,942,073...195,964,808 		JBrowse link
G Sirt4 sirtuin 4 NOT|enables ISO (PMID:17715127)
(PMID:23746352)		 RGD PMID:17715127 PMID:23746352 NCBI chr12:41,125,533...41,139,440
Ensembl chr12:41,131,262...41,139,439 		JBrowse link
G Sirt5 sirtuin 5 enables IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr17:21,310,028...21,337,137
Ensembl chr17:21,310,028...21,337,101 		JBrowse link
G Sirt6 sirtuin 6 enables ISO (PMID:19109893), (PMID:23142079), (PMID:24052263), (PMID:25009184), (PMID:26787900), (PMID:27322069), (PMID:29474172)
(PMID:27457971), (PMID:30782483), (PMID:31442424), (PMID:31851938)		 RGD PMID:19109893 PMID:23142079 PMID:24052263 PMID:25009184 PMID:26787900 More... NCBI chr 7:8,082,312...8,087,776
Ensembl chr 7:8,082,364...8,098,914 		JBrowse link
G Sirt7 sirtuin 7 enables ISO
ISS		 (PMID:24207024), (PMID:26867678), (PMID:28426094), (PMID:28790157), (PMID:28886238), (PMID:30540930), (PMID:30944854), (PMID:31075303)
(PMID:25200183), (PMID:31075303)
GO_REF:0000024		 RGD
UniProt		 PMID:24207024 PMID:25200183 PMID:26867678 PMID:28426094 PMID:28790157 More... GO_REF:0000024 NCBI chr10:105,896,476...105,903,301
Ensembl chr10:105,896,476...105,903,172 		JBrowse link
NAD-dependent protein lysine delactylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sirt1 sirtuin 1 enables ISO
IEA		 (PMID:38512451)
GO_REF:0000107		 RGD
Ensembl		 PMID:38512451 GO_REF:0000107 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Sirt3 sirtuin 3 enables ISO
IEA		 (PMID:36896611), (PMID:37720100)
GO_REF:0000107		 RGD
Ensembl		 PMID:36896611 PMID:37720100 GO_REF:0000107 NCBI chr 1:195,942,066...195,964,472
Ensembl chr 1:195,942,073...195,964,808 		JBrowse link
NAD-dependent protein-lysine depropionylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sirt1 sirtuin 1 enables ISS
ISO
IEA		 GO_REF:0000024
(PMID:30026585)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:30026585 GO_REF:0000024 GO_REF:0000107 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Sirt7 sirtuin 7 enables ISS
ISO		 GO_REF:0000024
(PMID:30026585)		 UniProt
RGD		 PMID:30026585 GO_REF:0000024 NCBI chr10:105,896,476...105,903,301
Ensembl chr10:105,896,476...105,903,172 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20634
    catalytic activity 6032
      catalytic activity, acting on a protein 2509
        NAD-dependent protein lysine deacylase activity 7
          NAD-dependent protein lysine deacetylase activity + 7
          NAD-dependent protein-lysine depropionylase activity 2
Path 2
Term Annotations click to browse term
  molecular_function 20634
    catalytic activity 6032
      deacylase activity 71
        deacetylase activity 38
          NAD-dependent protein lysine deacylase activity 7
            NAD-dependent protein lysine deacetylase activity + 7
            NAD-dependent protein-lysine depropionylase activity 2
paths to the root