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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of inflammasome-mediated signaling pathway
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Accession:GO:0141087 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of an inflammasome-mediated signaling pathway.
Synonyms:exact_synonym: positive regulation of inflammasome-mediated signal transduction


show annotations for term's descendants           Sort by:
positive regulation of AIM2 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gbp2 guanylate binding protein 2 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:25774715), (PMID:25774716)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:25774715 PMID:25774716 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:234,005,727...234,021,812
Ensembl chr 2:231,332,284...231,348,571 		JBrowse link
G Gbp5 guanylate binding protein 5 involved_in ISO
IEA		 (PMID:25774715), (PMID:25774716)
GO_REF:0000107		 RGD
Ensembl		 PMID:25774715 PMID:25774716 GO_REF:0000107 NCBI chr 2:233,910,999...233,930,320
Ensembl chr 2:231,237,748...231,257,061 		JBrowse link
positive regulation of NLRP3 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atat1 alpha tubulin acetyltransferase 1 acts_upstream_of_or_within ISO
IEA		 (PMID:23502856)
GO_REF:0000107		 RGD
Ensembl		 PMID:23502856 GO_REF:0000107 NCBI chr20:2,849,399...2,862,614
Ensembl chr20:2,844,616...2,861,964 		JBrowse link
G Brcc3 BRCA1/BRCA2-containing complex subunit 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:28943315)
(PMID:23246432)		 UniProt
RGD		 PMID:23246432 PMID:28943315 GO_REF:0000024 NCBI chr 9:2,073,927...2,076,469
Ensembl chr 9:1,986,575...1,991,080 		JBrowse link
G Btk Bruton tyrosine kinase involved_in ISO
IEA		 (PMID:34554188)
GO_REF:0000107		 RGD
Ensembl		 PMID:34554188 GO_REF:0000107 NCBI chr  X:102,016,070...102,055,448
Ensembl chr  X:97,722,802...97,761,853 		JBrowse link
G Casp4 caspase 4 involved_in ISO (PMID:26173909) RGD PMID:26173909 NCBI chr 8:10,883,817...10,919,978
Ensembl chr 8:2,598,876...2,635,092 		JBrowse link
G Cd36 CD36 molecule involved_in ISS
ISO		 GO_REF:0000024
(PMID:23812099)		 UniProt
RGD		 PMID:23812099 GO_REF:0000024 NCBI chr 4:18,209,088...18,302,142
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Cd36l1 CD36 molecule like 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 4:18,316,806...18,357,863
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked involved_in ISO
IEA		 (PMID:31511697)
GO_REF:0000107		 RGD
Ensembl		 PMID:31511697 GO_REF:0000107 NCBI chr  X:12,152,346...12,165,983
Ensembl chr  X:9,479,532...9,493,168 		JBrowse link
G Dhx33 DEAH-box helicase 33 involved_in ISO
IEA		 (PMID:23871209)
GO_REF:0000107		 RGD
Ensembl		 PMID:23871209 GO_REF:0000107 NCBI chr10:56,206,680...56,223,189
Ensembl chr10:55,705,756...55,724,567 		JBrowse link
G Gbp5 guanylate binding protein 5 involved_in ISO
IEA		 (PMID:22461501)
GO_REF:0000107		 RGD
Ensembl		 PMID:22461501 GO_REF:0000107 NCBI chr 2:233,910,999...233,930,320
Ensembl chr 2:231,237,748...231,257,061 		JBrowse link
G Kcnk6 potassium two pore domain channel subfamily K member 6 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 1:93,652,888...93,661,419
Ensembl chr 1:84,525,590...84,534,677 		JBrowse link
G Lats1 large tumor suppressor kinase 1 involved_in ISO
IEA		 (PMID:39173637)
GO_REF:0000107		 RGD
Ensembl		 PMID:39173637 GO_REF:0000107 NCBI chr 1:3,980,801...4,014,029
Ensembl chr 1:2,160,411...2,193,640 		JBrowse link
G Lats2 large tumor suppressor kinase 2 involved_in ISO
IEA		 (PMID:39173637)
GO_REF:0000107		 RGD
Ensembl		 PMID:39173637 GO_REF:0000107 NCBI chr15:35,940,632...35,992,225
Ensembl chr15:31,825,092...31,877,220 		JBrowse link
G LOC134486712 platelet glycoprotein 4-like involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 4:18,372,301...18,408,431 JBrowse link
G Mapk8 mitogen-activated protein kinase 8 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:28943315)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:28943315 GO_REF:0000024 GO_REF:0000107 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Marchf5 membrane associated ring-CH-type finger 5 involved_in IEA
ISO		 GO_REF:0000107
(PMID:37575012)		 Ensembl
RGD		 PMID:37575012 GO_REF:0000107 NCBI chr 1:244,343,674...244,365,160
Ensembl chr 1:234,931,271...234,952,632 		JBrowse link
G Mark4 microtubule affinity regulating kinase 4 involved_in ISO
IEA		 (PMID:28656979)
GO_REF:0000107		 RGD
Ensembl		 PMID:28656979 GO_REF:0000107 NCBI chr 1:88,203,352...88,239,858
Ensembl chr 1:79,068,904...79,108,556 		JBrowse link
G Mavs mitochondrial antiviral signaling protein involved_in ISO (PMID:23582325) RGD PMID:23582325 NCBI chr 3:138,904,673...138,919,129
Ensembl chr 3:118,451,743...118,466,094 		JBrowse link
G Mir21 microRNA 21 IDA RGD PMID:29084974 RGD:41404715 NCBI chr10:71,902,600...71,902,691
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:33718825)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:33718825 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Nek7 NIMA-related kinase 7 involved_in ISS
IEA
ISO
IBA		 GO_REF:0000024
GO_REF:0000107
(PMID:26642356), (PMID:26814970)
(PMID:31189953), (PMID:36442502), (PMID:39173637)
GO_REF:0000033		 UniProt
Ensembl
RGD
GO_Central		 PMID:26642356 PMID:26814970 PMID:31189953 PMID:36442502 PMID:39173637 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr13:52,573,730...52,700,869
Ensembl chr13:50,022,218...50,149,296 		JBrowse link
G P2rx7 purinergic receptor P2X 7 involved_in ISS
ISO		 GO_REF:0000024
(PMID:29958799)		 UniProt
RGD		 PMID:29958799 GO_REF:0000024 NCBI chr12:39,550,531...39,594,984
Ensembl chr12:33,879,745...33,934,619 		JBrowse link
G Plcg2 phospholipase C, gamma 2 acts_upstream_of_or_within ISO (PMID:32514138) RGD PMID:32514138 NCBI chr19:62,456,196...62,592,684
Ensembl chr19:45,547,416...45,683,930 		JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha involved_in ISS
ISO		 GO_REF:0000024
(PMID:28465465)		 UniProt
RGD		 PMID:28465465 GO_REF:0000024 NCBI chr10:36,856,534...36,878,789
Ensembl chr10:36,358,101...36,377,862 		JBrowse link
G Prkd1 protein kinase D1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:28716882)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:28716882 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:73,460,640...73,774,433
Ensembl chr 6:67,725,905...68,039,042 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 involved_in ISO (PMID:27043286) RGD PMID:27043286 NCBI chr 2:194,055,165...194,103,209
Ensembl chr 2:191,366,808...191,414,779 		JBrowse link
G Stmp1 short transmembrane mitochondrial protein 1 involved_in ISO (PMID:31836654) RGD PMID:31836654 NCBI chr 4:64,894,663...64,904,495 JBrowse link
G Tlr4 toll-like receptor 4 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:23812099)		 UniProt
Ensembl
RGD		 PMID:23812099 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tlr6 toll-like receptor 6 involved_in ISO
IEA		 (PMID:23812099)
GO_REF:0000107		 RGD
Ensembl		 PMID:23812099 GO_REF:0000107 NCBI chr14:43,715,809...43,727,019
Ensembl chr14:43,362,164...43,375,685 		JBrowse link
G Usp50 ubiquitin specific peptidase 50 acts_upstream_of_or_within ISO
IEA		 (PMID:28094437)
GO_REF:0000107		 RGD
Ensembl		 PMID:28094437 GO_REF:0000107 NCBI chr 3:134,465,469...134,488,859
Ensembl chr 3:114,011,702...114,035,476 		JBrowse link
G Zdhhc1 zinc finger, DHHC-type containing 1 involved_in ISO (PMID:39173637) RGD PMID:39173637 NCBI chr19:50,260,445...50,285,634
Ensembl chr19:33,350,533...33,375,616 		JBrowse link
G Zdhhc5 zinc finger DHHC-type palmitoyltransferase 5 involved_in ISO
IEA		 (PMID:38092000)
GO_REF:0000107		 RGD
Ensembl		 PMID:38092000 GO_REF:0000107 NCBI chr 3:90,178,734...90,206,889
Ensembl chr 3:69,771,890...69,799,921 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    cellular process 19550
      signal transduction 7301
        positive regulation of signal transduction 1768
          positive regulation of pattern recognition receptor signaling pathway 87
            positive regulation of inflammasome-mediated signaling pathway 32
              positive regulation of AIM2 inflammasome complex assembly 2
              positive regulation of NLRP3 inflammasome complex assembly 31
Path 2
Term Annotations click to browse term
  biological_process 20558
    response to stimulus 11067
      response to external stimulus 2804
        response to external biotic stimulus 1894
          response to other organism 1890
            defense response to other organism 1336
              defense response to symbiont 1112
                innate immune response 1025
                  regulation of innate immune response 491
                    positive regulation of innate immune response 401
                      activation of innate immune response 329
                        innate immune response-activating signaling pathway 301
                          pattern recognition receptor signaling pathway 290
                            cytoplasmic pattern recognition receptor signaling pathway 189
                              regulation of cytoplasmic pattern recognition receptor signaling pathway 130
                                regulation of inflammasome-mediated signaling pathway 51
                                  positive regulation of inflammasome-mediated signaling pathway 32
                                    positive regulation of AIM2 inflammasome complex assembly 2
                                    positive regulation of NLRP3 inflammasome complex assembly 31
paths to the root