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ONTOLOGY REPORT - ANNOTATIONS

Term:polyspecific organic cation:proton antiporter activity
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Accession:GO:0140968 term browser browse the term
Definition:Enables the transfer of various organic cations in exchange for a proton, according to the reaction: H+(out) + organic cation(in) = H+(in) + organic cation(out). The transported substrates are usually toxic molecules, drugs and xenobiotics.
Synonyms:xref: TC:2.A.66.1.20


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polyspecific organic cation:proton antiporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc47a1 solute carrier family 47 member 1 enables IDA
ISO
IEA		 PMID:17047166
(PMID:16330770), (PMID:17509534)
GO_REF:0000107
(PMID:16641166)		 RGD
Ensembl		 PMID:16330770 PMID:16641166 PMID:17509534 PMID:17047166 GO_REF:0000107, RGD:2316964 NCBI chr10:46,034,115...46,088,617
Ensembl chr10:46,034,122...46,087,637 		JBrowse link
G Slc47a2 solute carrier family 47 member 2 enables ISO (PMID:16807400)
(PMID:17715386)		 RGD PMID:16807400 PMID:17715386 NCBI chr10:45,990,806...46,033,937
Ensembl chr10:45,991,095...46,033,904 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20633
    transporter activity 1253
      transmembrane transporter activity 1153
        monoatomic ion transmembrane transporter activity 762
          active monoatomic ion transmembrane transporter activity 270
            polyspecific organic cation:proton antiporter activity 2
Path 2
Term Annotations click to browse term
  molecular_function 20633
    transporter activity 1253
      transmembrane transporter activity 1153
        monoatomic ion transmembrane transporter activity 762
          monoatomic cation transmembrane transporter activity 642
            proton transmembrane transporter activity 164
              polyspecific organic cation:proton antiporter activity 2
paths to the root