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ONTOLOGY REPORT - ANNOTATIONS

Term:endolysosomal toll-like receptor signaling pathway
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Accession:GO:0140894 term browser browse the term
Definition:The series of molecular signals initiated by a ligand binding to an endolysosomal pattern recognition receptor (PRR) of the toll-like family. PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species.
Synonyms:exact_synonym: endolysosomal pattern recognition receptor signaling pathway


show annotations for term's descendants           Sort by:
endolysosomal toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Washc4 WASH complex subunit 4 acts_upstream_of_or_within ISO (PMID:33749590) RGD PMID:33749590 NCBI chr 7:20,187,905...20,240,228
Ensembl chr 7:20,187,922...20,240,226 		JBrowse link
negative regulation of toll-like receptor 3 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F2rl1 F2R like trypsin receptor 1 involved_in ISO
IEA 		(PMID:19865078)
GO_REF:0000107 		RGD
Ensembl		 PMID:19865078 GO_REF:0000107 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226 		JBrowse link
G Tnfaip3 TNF alpha induced protein 3 involved_in ISO
IEA 		(PMID:15474016)
GO_REF:0000107 		RGD
Ensembl		 PMID:15474016 GO_REF:0000107 NCBI chr 1:15,528,921...15,543,993
Ensembl chr 1:13,709,206...13,725,282 		JBrowse link
G Ubqln1 ubiquilin 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:21695056) 		Ensembl
RGD		 PMID:21695056 GO_REF:0000107 NCBI chr17:6,439,002...6,477,096
Ensembl chr17:6,439,002...6,477,090 		JBrowse link
negative regulation of toll-like receptor 9 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gramd4 GRAM domain containing 4 involved_in IBA
ISO 		GO_REF:0000033
(PMID:25917084) 		GO_Central
RGD		 PMID:25917084 GO_REF:0000033 NCBI chr 7:117,150,398...117,224,056
Ensembl chr 7:117,150,374...117,224,053 		JBrowse link
G Ppt1 palmitoyl-protein thioesterase 1 involved_in ISO
IEA 		(PMID:14716310)
GO_REF:0000107 		RGD
Ensembl		 PMID:14716310 GO_REF:0000107 NCBI chr 5:135,121,164...135,142,048
Ensembl chr 5:135,121,163...135,142,048 		JBrowse link
G Ptprs protein tyrosine phosphatase, receptor type, S involved_in ISO (PMID:26231120) RGD PMID:26231120 NCBI chr 9:1,245,408...1,307,015
Ensembl chr 9:1,245,410...1,306,947 		JBrowse link
G Rab7b Rab7b, member RAS oncogene family involved_in ISO
IEA 		(PMID:19587007)
GO_REF:0000107 		RGD
Ensembl		 PMID:19587007 GO_REF:0000107 NCBI chr13:43,121,168...43,147,581
Ensembl chr13:43,121,226...43,147,581 		JBrowse link
positive regulation of toll-like receptor 13 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Treml4 triggering receptor expressed on myeloid cells-like 4 involved_in ISO (PMID:25848864) RGD PMID:25848864 NCBI chr 9:12,718,968...12,743,879
Ensembl chr 9:12,721,815...12,743,253 		JBrowse link
positive regulation of toll-like receptor 3 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav1 caveolin 1 involved_in ISO
IEA 		(PMID:25204797)
GO_REF:0000107 		RGD
Ensembl		 PMID:25204797 GO_REF:0000107 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISO
IEA 		(PMID:19865078)
GO_REF:0000107 		RGD
Ensembl		 PMID:19865078 GO_REF:0000107 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226 		JBrowse link
G Flot1 flotillin 1 involved_in ISO
IEA 		(PMID:25204797)
GO_REF:0000107 		RGD
Ensembl		 PMID:25204797 GO_REF:0000107 NCBI chr20:2,917,864...2,927,993
Ensembl chr20:2,917,137...2,927,978 		JBrowse link
G Peli1 pellino E3 ubiquitin protein ligase 1 acts_upstream_of_or_within ISO
IEA 		MGI:4361448 (PMID:19734906)
GO_REF:0000107 		RGD
Ensembl		 PMID:19734906 GO_REF:0000107 NCBI chr14:99,455,970...99,510,474
Ensembl chr14:95,254,589...95,308,285
Ensembl chr 1:95,254,589...95,308,285 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 involved_in ISO (PMID:23871208) RGD PMID:23871208 NCBI chr 2:191,366,761...191,414,782
Ensembl chr 2:191,366,808...191,414,779 		JBrowse link
G Tirap TIR domain containing adaptor protein involved_in ISO (PMID:17322885) RGD PMID:17322885 NCBI chr 8:33,531,724...33,548,508
Ensembl chr 8:33,531,725...33,547,432 		JBrowse link
G Trim3 tripartite motif-containing 3 involved_in IEA
ISO 		GO_REF:0000107
(PMID:32878999) 		Ensembl
RGD		 PMID:32878999 GO_REF:0000107 NCBI chr 1:169,362,751...169,385,430
Ensembl chr 1:159,944,908...159,973,600 		JBrowse link
G Wdfy1 WD repeat and FYVE domain containing 1 involved_in ISO
IEA
IBA 		(PMID:25736436)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:25736436 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:81,034,852...81,092,823
Ensembl chr 9:81,034,849...81,092,775 		JBrowse link
positive regulation of toll-like receptor 7 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddx3x DEAD-box helicase 3, X-linked involved_in ISO (PMID:30341167) RGD PMID:30341167 NCBI chr  X:9,479,532...9,493,169
Ensembl chr  X:9,479,532...9,493,168 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 involved_in ISO (PMID:23871208) RGD PMID:23871208 NCBI chr 2:191,366,761...191,414,782
Ensembl chr 2:191,366,808...191,414,779 		JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:21435586)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:21435586 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:43,046,514...43,059,737
Ensembl chr 6:43,047,658...43,059,699 		JBrowse link
G Slc15a4 solute carrier family 15 member 4 involved_in IEA
ISO
ISS 		GO_REF:0000107
(PMID:21045126), (PMID:25238095)
GO_REF:0000024
(PMID:25238095), (PMID:32433612) 		Ensembl
RGD
UniProt		 PMID:21045126 PMID:25238095 PMID:32433612 GO_REF:0000024 GO_REF:0000107 NCBI chr12:29,048,634...29,082,480
Ensembl chr12:29,063,015...29,082,480 		JBrowse link
G Tasl TLR adaptor interacting with endolysosomal SLC15A4 involved_in ISO
IEA 		(PMID:32433612)
GO_REF:0000107 		RGD
Ensembl		 PMID:32433612 GO_REF:0000107 NCBI chr  X:50,403,962...50,423,141
Ensembl chr  X:50,361,248...50,423,269 		JBrowse link
G Treml4 triggering receptor expressed on myeloid cells-like 4 involved_in ISO
IBA 		(PMID:25848864)
GO_REF:0000033 		RGD
GO_Central		 PMID:25848864 GO_REF:0000033 NCBI chr 9:12,718,968...12,743,879
Ensembl chr 9:12,721,815...12,743,253 		JBrowse link
positive regulation of toll-like receptor 8 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddx3x DEAD-box helicase 3, X-linked involved_in ISO (PMID:30341167) RGD PMID:30341167 NCBI chr  X:9,479,532...9,493,169
Ensembl chr  X:9,479,532...9,493,168 		JBrowse link
G Slc15a4 solute carrier family 15 member 4 involved_in IEA
ISS
ISO 		GO_REF:0000107
GO_REF:0000024
(PMID:32433612) 		Ensembl
UniProt
RGD		 PMID:32433612 GO_REF:0000024 GO_REF:0000107 NCBI chr12:29,048,634...29,082,480
Ensembl chr12:29,063,015...29,082,480 		JBrowse link
G Tasl TLR adaptor interacting with endolysosomal SLC15A4 involved_in ISO
IEA 		(PMID:32433612)
GO_REF:0000107 		RGD
Ensembl		 PMID:32433612 GO_REF:0000107 NCBI chr  X:50,403,962...50,423,141
Ensembl chr  X:50,361,248...50,423,269 		JBrowse link
positive regulation of toll-like receptor 9 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmgb1 high mobility group box 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 involved_in ISO (PMID:23871208) RGD PMID:23871208 NCBI chr 2:191,366,761...191,414,782
Ensembl chr 2:191,366,808...191,414,779 		JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:21435586) 		UniProt
Ensembl
RGD		 PMID:21435586 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:43,046,514...43,059,737
Ensembl chr 6:43,047,658...43,059,699 		JBrowse link
G Rtn4 reticulon 4 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:25917084) 		UniProt
Ensembl
RGD		 PMID:25917084 GO_REF:0000024 GO_REF:0000107 NCBI chr14:103,450,074...103,497,687
Ensembl chr14:103,449,930...103,497,686 		JBrowse link
G Slc15a4 solute carrier family 15 member 4 involved_in ISO
IEA
ISS 		(PMID:25238095)
GO_REF:0000107
GO_REF:0000024
(PMID:21045126), (PMID:21277849), (PMID:25238095) 		RGD
Ensembl
UniProt		 PMID:21045126 PMID:21277849 PMID:25238095 GO_REF:0000024 GO_REF:0000107 NCBI chr12:29,048,634...29,082,480
Ensembl chr12:29,063,015...29,082,480 		JBrowse link
G Tlr9 toll-like receptor 9 involved_in ISO
IEA 		(PMID:18931679)
GO_REF:0000107 		RGD
Ensembl		 PMID:18931679 GO_REF:0000107 NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796 		JBrowse link
G Treml4 triggering receptor expressed on myeloid cells-like 4 involved_in ISO (PMID:25848864) RGD PMID:25848864 NCBI chr 9:12,718,968...12,743,879
Ensembl chr 9:12,721,815...12,743,253 		JBrowse link
G Zdhhc3 zinc finger DHHC-type palmitoyltransferase 3 involved_in ISO
IEA 		(PMID:38169466)
GO_REF:0000107 		RGD
Ensembl		 PMID:38169466 GO_REF:0000107 NCBI chr 8:131,602,663...131,650,998
Ensembl chr 8:122,715,111...122,773,529 		JBrowse link
regulation of toll-like receptor 3 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Flot2 flotillin 2 NOT|involved_in ISO (PMID:25204797) RGD PMID:25204797 NCBI chr10:62,926,047...62,947,759
Ensembl chr10:62,920,665...62,947,756 		JBrowse link
G Hcfc2 host cell factor C2 acts_upstream_of_or_within ISO MGI:5445585 (PMID:28970238) RGD PMID:28970238 NCBI chr 7:20,983,986...21,019,826
Ensembl chr 7:20,991,017...21,019,801 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in ISO (PMID:37158982) RGD PMID:37158982 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
toll-like receptor 3 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd86 CD86 molecule involved_in ISO (PMID:25158758) RGD PMID:25158758 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818 		JBrowse link
G Colec12 collectin sub-family member 12 involved_in ISO (PMID:25204797) RGD PMID:25204797 NCBI chr18:732,950...920,620
Ensembl chr18:732,950...920,618 		JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 involved_in ISO (PMID:22842346) RGD PMID:22842346 NCBI chr10:30,882,484...30,914,018
Ensembl chr10:30,882,606...30,909,137 		JBrowse link
G Lgals9 galectin 9 involved_in IMP PMID:25158758 UniProt PMID:25158758 RGD:10054077 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045 		JBrowse link
G Oas1a 2'-5' oligoadenylate synthetase 1A involved_in ISO (PMID:30078389) RGD PMID:30078389 NCBI chr12:35,669,798...35,680,505
Ensembl chr12:35,669,801...35,680,517 		JBrowse link
G Rftn1 raftlin lipid raft linker 1 acts_upstream_of_or_within ISO (PMID:21266579) RGD PMID:21266579 NCBI chr 9:10,804,611...11,002,084
Ensembl chr 9:10,804,611...11,002,084 		JBrowse link
G Rnf170 ring finger protein 170 acts_upstream_of_or_within ISO
IEA 		(PMID:31076723)
GO_REF:0000107 		RGD
Ensembl		 PMID:31076723 GO_REF:0000107 NCBI chr16:72,631,638...72,656,893
Ensembl chr16:65,928,895...65,954,083 		JBrowse link
G Scara3 scavenger receptor class A, member 3 NOT|involved_in ISO (PMID:25204797) RGD PMID:25204797 NCBI chr15:40,139,873...40,172,866
Ensembl chr15:40,140,161...40,172,894 		JBrowse link
G Scimp SLP adaptor and CSK interacting membrane protein involved_in ISO (PMID:28098138) RGD PMID:28098138 NCBI chr10:55,507,646...55,527,764
Ensembl chr10:55,507,519...55,528,171 		JBrowse link
G Ticam1 TIR domain containing adaptor molecule 1 involved_in ISO (PMID:12471095) RGD PMID:12471095 NCBI chr 9:1,102,559...1,111,023
Ensembl chr 9:1,102,366...1,123,147 		JBrowse link
G Tlr3 toll-like receptor 3 involved_in ISO
IEA 		(PMID:17128265), (PMID:18172197)
GO_REF:0000107 		RGD
Ensembl		 PMID:17128265 PMID:18172197 GO_REF:0000107 NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545 		JBrowse link
G Tnf tumor necrosis factor involved_in IMP PMID:25158758 UniProt PMID:25158758 RGD:10054077 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnip2 TNFAIP3 interacting protein 2 involved_in IBA
IEA
ISO 		GO_REF:0000033
GO_REF:0000107
(PMID:16633345) 		GO_Central
Ensembl
RGD		 PMID:16633345 GO_REF:0000033 GO_REF:0000107 NCBI chr14:76,228,350...76,245,553
Ensembl chr14:76,228,371...76,275,265 		JBrowse link
G Unc93b1 unc-93 homolog B1, TLR signaling regulator involved_in ISO
IEA
IBA 		(PMID:18082565)
GO_REF:0000107
(PMID:16415873)
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:16415873 PMID:18082565 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:201,167,388...201,178,343
Ensembl chr 1:201,152,693...201,178,338 		JBrowse link
toll-like receptor 7 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Havcr2 hepatitis A virus cellular receptor 2 involved_in ISO (PMID:22842346) RGD PMID:22842346 NCBI chr10:30,882,484...30,914,018
Ensembl chr10:30,882,606...30,909,137 		JBrowse link
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 involved_in ISO
IEA 		(PMID:22187458)
GO_REF:0000107 		RGD
Ensembl		 PMID:22187458 GO_REF:0000107 NCBI chr 1:240,090,854...240,245,007
Ensembl chr 1:240,093,065...240,204,828 		JBrowse link
G Scimp SLP adaptor and CSK interacting membrane protein involved_in ISO (PMID:28098138) RGD PMID:28098138 NCBI chr10:55,507,646...55,527,764
Ensembl chr10:55,507,519...55,528,171 		JBrowse link
G Tlr7 toll-like receptor 7 involved_in ISO
IEA
IBA 		(PMID:12032557)
GO_REF:0000107
GO_REF:0000033
(PMID:14976261) 		RGD
Ensembl
GO_Central		 PMID:12032557 PMID:14976261 GO_REF:0000033 GO_REF:0000107 NCBI chr  X:27,027,380...27,054,309
Ensembl chr  X:27,027,425...27,054,754 		JBrowse link
G Unc93b1 unc-93 homolog B1, TLR signaling regulator involved_in ISO
IEA
IBA 		(PMID:19006693)
GO_REF:0000107
(PMID:16415873)
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:16415873 PMID:19006693 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:201,167,388...201,178,343
Ensembl chr 1:201,152,693...201,178,338 		JBrowse link
toll-like receptor 8 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Myd88 MYD88, innate immune signal transduction adaptor involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:33718825) 		UniProt
Ensembl
RGD		 PMID:33718825 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Tlr7 toll-like receptor 7 involved_in ISO
IEA 		(PMID:12032557)
GO_REF:0000107 		RGD
Ensembl		 PMID:12032557 GO_REF:0000107 NCBI chr  X:27,027,380...27,054,309
Ensembl chr  X:27,027,425...27,054,754 		JBrowse link
G Tlr8 toll-like receptor 8 involved_in ISO (PMID:12032557), (PMID:24942581), (PMID:33718825) RGD PMID:12032557 PMID:24942581 PMID:33718825 NCBI chr  X:27,091,780...27,116,092
Ensembl chr  X:27,091,778...27,116,549 		JBrowse link
toll-like receptor 9 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Epg5 ectopic P-granules 5 autophagy tethering factor acts_upstream_of_positive_effect ISO
IEA 		(PMID:29130391)
GO_REF:0000107 		RGD
Ensembl		 PMID:29130391 GO_REF:0000107 NCBI chr18:71,403,990...71,502,079
Ensembl chr18:71,404,010...71,501,502 		JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 involved_in ISO (PMID:22842346) RGD PMID:22842346 NCBI chr10:30,882,484...30,914,018
Ensembl chr10:30,882,606...30,909,137 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 involved_in IEA
ISO 		GO_REF:0000107
(PMID:23372731) 		Ensembl
RGD		 PMID:23372731 GO_REF:0000107 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047 		JBrowse link
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 involved_in ISO
IEA 		(PMID:22187458), (PMID:22187460)
GO_REF:0000107 		RGD
Ensembl		 PMID:22187458 PMID:22187460 GO_REF:0000107 NCBI chr 1:240,090,854...240,245,007
Ensembl chr 1:240,093,065...240,204,828 		JBrowse link
G Tlr9 toll-like receptor 9 involved_in ISO
IEA 		(PMID:23857366)
GO_REF:0000107 		RGD
Ensembl		 PMID:23857366 GO_REF:0000107 NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796 		JBrowse link
G Tnip2 TNFAIP3 interacting protein 2 involved_in ISO
IEA 		(PMID:16633345)
GO_REF:0000107 		RGD
Ensembl		 PMID:16633345 GO_REF:0000107 NCBI chr14:76,228,350...76,245,553
Ensembl chr14:76,228,371...76,275,265 		JBrowse link
G Unc93b1 unc-93 homolog B1, TLR signaling regulator involved_in ISO
IEA
IBA 		(PMID:19006693)
GO_REF:0000107
(PMID:16415873), (PMID:38169466)
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:16415873 PMID:19006693 PMID:38169466 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:201,167,388...201,178,343
Ensembl chr 1:201,152,693...201,178,338 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20543
    cellular process 19534
      signal transduction 7313
        intracellular signal transduction 3197
          intracellular receptor signaling pathway 421
            cytoplasmic pattern recognition receptor signaling pathway 189
              endolysosomal toll-like receptor signaling pathway 47
                toll-like receptor 11 signaling pathway + 0
                toll-like receptor 12 signaling pathway + 0
                toll-like receptor 13 signaling pathway + 1
                toll-like receptor 3 signaling pathway + 27
                toll-like receptor 7 signaling pathway + 11
                toll-like receptor 8 signaling pathway + 6
                toll-like receptor 9 signaling pathway + 18
Path 2
Term Annotations click to browse term
  biological_process 20543
    response to stimulus 11082
      response to biotic stimulus 1946
        response to external biotic stimulus 1897
          response to other organism 1893
            defense response to other organism 1133
              defense response to symbiont 1112
                innate immune response 1025
                  regulation of innate immune response 491
                    positive regulation of innate immune response 401
                      activation of innate immune response 329
                        innate immune response-activating signaling pathway 301
                          pattern recognition receptor signaling pathway 290
                            cytoplasmic pattern recognition receptor signaling pathway 189
                              endolysosomal toll-like receptor signaling pathway 47
                                toll-like receptor 11 signaling pathway + 0
                                toll-like receptor 12 signaling pathway + 0
                                toll-like receptor 13 signaling pathway + 1
                                toll-like receptor 3 signaling pathway + 27
                                toll-like receptor 7 signaling pathway + 11
                                toll-like receptor 8 signaling pathway + 6
                                toll-like receptor 9 signaling pathway + 18
paths to the root