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ONTOLOGY REPORT - ANNOTATIONS
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Term:
FAD-dependent H3K4me/H3K4me3 demethylase activity
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Accession:
GO:0140682
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Definition:
Catalysis of the removal of a methyl group from a di- or a monomethyl-lysine residue at position 4 of the histone H3 protein. This is a flavin adenine dinucleotide (FAD)-dependent amine oxidation reaction.
Synonyms:
exact_synonym:
histone H3-di/monomethyl-lysine-4 FAD-dependent demethylase activity
broad_synonym:
histone H3K4me2 demethylase activity
related_synonym:
histone H3K4me demethylase activity
xref:
EC:1.14.99.66; RHEA:60244
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Genes (2)
FAD-dependent H3K4me/H3K4me3 demethylase activity
Symbol
Object Name
Qualifiers
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
Kdm1a
lysine demethylase 1A
enables
ISO
(PMID:20228790), (PMID:27292636)
(PMID:24843136)
UniProt
MGI
PMID:20228790
PMID:24843136
PMID:27292636
NCBI chrNW_004955452:3,044,042...3,104,650
Ensembl chrNW_004955452:3,044,264...3,104,418
G
Kdm1b
lysine demethylase 1B
enables
ISO
(PMID:23260659), (PMID:23266887), (PMID:23357850), (PMID:30970244)
(PMID:19407342), (PMID:19727073)
UniProt
MGI
PMID:19407342
PMID:19727073
PMID:23260659
PMID:23266887
PMID:23357850
PMID:30970244
More...
NCBI chrNW_004955483:8,000,862...8,052,486
Ensembl chrNW_004955483:8,002,577...8,052,486
Term paths to the root
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one longest
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one shortest and longest
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Path 1
Term
Annotations
molecular_function
14382
catalytic activity
3778
oxidoreductase activity
479
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
114
FAD-dependent H3K4me/H3K4me3 demethylase activity
2
Path 2
Term
Annotations
molecular_function
14382
catalytic activity
3778
demethylase activity
32
protein demethylase activity
22
histone demethylase activity
22
histone H3 demethylase activity
20
histone H3K4 demethylase activity
6
FAD-dependent H3K4me/H3K4me3 demethylase activity
2