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ONTOLOGY REPORT - ANNOTATIONS


Term:futile creatine cycle
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Accession:GO:0140651 term browser browse the term
Definition:The phosphorylation and dephosphorylation of creatine in a futile cycle, which dissipates the high energy charge of phosphocreatine as heat without performing any mechanical or chemical work. The futile creatine cycle takes place in thermogenic fat cells and is part of adaptive thermogenesis.



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futile creatine cycle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alpl alkaline phosphatase, biomineralization associated involved_in ISO (MGI:6716981|PMID:33981039) RGD PMID:33981039 MGI:6716981 NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446
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G Ckb creatine kinase B involved_in ISO (MGI:6706133|PMID:33597756) RGD PMID:33597756 MGI:6706133 NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315
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  biological_process 19512
    metabolic process 11791
      futile creatine cycle 2
Path 2
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  biological_process 19512
    metabolic process 11791
      adaptive thermogenesis 166
        futile creatine cycle 2
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