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ONTOLOGY REPORT - ANNOTATIONS


Term:inflammasome complex assembly
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Accession:GO:0140632 term browser browse the term
Definition:The aggregation, arrangement and bonding together of a set of components to form an inflammasome complex.


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CARD8 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nlrp1b NLR family, pyrin domain containing 1B involved_in ISO (PMID:33420028), (PMID:33420033) RGD PMID:33420028 PMID:33420033 NCBI chr10:57,755,957...57,847,867 JBrowse link
negative regulation of NLRP3 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cptp ceramide-1-phosphate transfer protein involved_in ISO
ISS
(PMID:29164996)
GO_REF:0000024
RGD
UniProt
PMID:29164996 GO_REF:0000024 NCBI chr 5:173,314,219...173,318,384
Ensembl chr 5:173,314,228...173,318,313
JBrowse link
G Mefv MEFV innate immuity regulator, pyrin involved_in ISS
ISO
GO_REF:0000024
(PMID:26347139)
UniProt
RGD
PMID:26347139 GO_REF:0000024 NCBI chr10:12,045,813...12,056,229
Ensembl chr10:12,046,541...12,056,311
JBrowse link
G Nlrc3 NLR family, CARD domain containing 3 involved_in ISO (PMID:25277106) RGD PMID:25277106 NCBI chr10:11,809,531...11,844,184
Ensembl chr10:11,810,926...11,842,482
JBrowse link
G Nlrp1b NLR family, pyrin domain containing 1B involved_in ISO (PMID:24517500) RGD PMID:24517500 NCBI chr10:57,755,957...57,847,867 JBrowse link
G Sirt2 sirtuin 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:5488534|PMID:23502856)
Ensembl
RGD
PMID:23502856 GO_REF:0000107 MGI:5488534 NCBI chr 1:86,948,866...86,971,954
Ensembl chr 1:86,948,918...86,971,952
JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 acts_upstream_of_or_within ISO (MGI:6391726|PMID:29887864)
(PMID:32514138)
RGD PMID:29887864 PMID:32514138 MGI:6391726 NCBI chr 9:14,611,541...14,618,076
Ensembl chr 9:14,611,561...14,618,013
JBrowse link
NLRP1 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nlrp1a NLR family, pyrin domain containing 1A involved_in ISO (PMID:27662089), (PMID:31484767) RGD PMID:27662089 PMID:31484767 NCBI chr10:57,692,474...57,747,608
Ensembl chr10:57,692,474...57,822,498
JBrowse link
NLRP3 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aim2 absent in melanoma 2 involved_in ISO (PMID:19158676) RGD PMID:19158676 NCBI chr13:91,919,834...91,963,080
Ensembl chr13:91,954,138...91,962,588
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 acts_upstream_of_or_within ISO MGI:5465108 (MGI:5446983|PMID:22753929) RGD PMID:22753929 MGI:5446983 NCBI chr10:45,884,324...45,918,290
Ensembl chr10:45,893,018...45,918,254
JBrowse link
positive regulation of NLRP3 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atat1 alpha tubulin acetyltransferase 1 acts_upstream_of_or_within ISO (MGI:5488534|PMID:23502856) RGD PMID:23502856 MGI:5488534 NCBI chr20:3,351,269...3,364,565
Ensembl chr20:3,351,303...3,364,565
JBrowse link
G Cd36 CD36 molecule involved_in ISS
ISO
GO_REF:0000024
(MGI:5546292|PMID:23812099)
UniProt
RGD
PMID:23812099 GO_REF:0000024 MGI:5546292 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked involved_in ISO (MGI:6368386|PMID:31511697) RGD PMID:31511697 MGI:6368386 NCBI chr  X:10,400,363...10,414,010
Ensembl chr  X:10,400,366...10,413,995
JBrowse link
G Dhx33 DEAH-box helicase 33 involved_in ISO (PMID:23871209) RGD PMID:23871209 NCBI chr10:57,622,022...57,638,485
Ensembl chr10:57,622,022...57,638,485
JBrowse link
G Gbp5 guanylate binding protein 5 involved_in ISO (PMID:22461501) RGD PMID:22461501 NCBI chr 2:248,178,441...248,196,873
Ensembl chr 2:248,178,389...248,197,160
JBrowse link
G Mir21 microRNA 21 IDA RGD PMID:29084974 RGD:41404715 NCBI chr10:73,902,210...73,902,301
Ensembl chr10:73,902,210...73,902,301
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor involved_in ISS
ISO
GO_REF:0000024
(PMID:33718825)
UniProt
RGD
PMID:33718825 GO_REF:0000024 NCBI chr 8:128,022,512...128,027,462
Ensembl chr 8:128,022,473...128,026,841
JBrowse link
G Plcg2 phospholipase C, gamma 2 acts_upstream_of_or_within ISO (PMID:32514138) RGD PMID:32514138 NCBI chr19:50,039,410...50,173,543
Ensembl chr19:50,045,020...50,173,220
JBrowse link
G Stmp1 short transmembrane mitochondrial protein 1 involved_in ISO (MGI:6384515|PMID:31836654) RGD PMID:31836654 MGI:6384515 NCBI chr 4:62,780,596...62,790,428
Ensembl chr 4:62,780,596...62,790,422
JBrowse link
G Tlr4 toll-like receptor 4 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:5546292|PMID:23812099)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:23812099 GO_REF:0000024 GO_REF:0000107 MGI:5546292 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tlr6 toll-like receptor 6 involved_in ISO (MGI:5546292|PMID:23812099) RGD PMID:23812099 MGI:5546292 NCBI chr14:45,024,351...45,041,188
Ensembl chr14:45,024,351...45,046,446
JBrowse link
G Usp50 ubiquitin specific peptidase 50 acts_upstream_of_or_within ISO (MGI:5888801|PMID:28094437)
(PMID:28094437)
RGD PMID:28094437 MGI:5888801 NCBI chr 3:119,225,055...119,247,442
Ensembl chr 3:119,224,943...119,247,449
JBrowse link
regulation of NLRP3 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:5432942|PMID:22801494)
UniProt
RGD
PMID:22801494 GO_REF:0000024 MGI:5432942 NCBI chr 6:1,428,845...1,466,193
Ensembl chr 6:1,428,834...1,466,201
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19610
    cellular process 18463
      cellular component organization or biogenesis 6727
        cellular component organization 6482
          cellular component assembly 2990
            protein-containing complex assembly 1594
              cellular protein-containing complex assembly 1113
                inflammasome complex assembly 22
                  CARD8 inflammasome complex assembly 1
                  NLRP1 inflammasome complex assembly 1
                  NLRP3 inflammasome complex assembly + 21
paths to the root