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ONTOLOGY REPORT - ANNOTATIONS

Term:DNA damage sensor activity
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Accession:GO:0140612 term browser browse the term
Definition:A molecule that recognises toxic DNA structures, for example, double-strand breaks or collapsed replication forks, and initiates a signaling response.
Synonyms:exact_synonym: DNA damage sensing activity


show annotations for term's descendants           Sort by:
DNA damage sensor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rad23b RAD23 homolog B, nucleotide excision repair protein enables ISO (PMID:19941824) RGD PMID:19941824 NCBI chr 5:70,090,232...70,128,340
Ensembl chr 5:70,090,232...70,128,319 		JBrowse link
G Sirt6 sirtuin 6 enables ISO (PMID:31995034), (PMID:32538779) RGD PMID:31995034 PMID:32538779 NCBI chr 7:8,082,312...8,087,776
Ensembl chr 7:8,082,364...8,098,914 		JBrowse link
G Xpc XPC complex subunit, DNA damage recognition and repair factor enables ISO (PMID:10873465), (PMID:19941824) RGD PMID:10873465 PMID:19941824 NCBI chr 4:123,993,670...124,020,922
Ensembl chr 4:123,993,666...124,021,010 		JBrowse link
ATP-dependent DNA damage sensor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dmc1 DNA meiotic recombinase 1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 7:111,124,888...111,167,465
Ensembl chr 7:111,124,888...111,167,952 		JBrowse link
G Mlh1 mutL homolog 1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617 		JBrowse link
G Mlh3 mutL homolog 3 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 6:104,881,483...104,917,686
Ensembl chr 6:104,881,483...104,917,728 		JBrowse link
G Msh2 mutS homolog 2 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938 		JBrowse link
G Msh4 mutS homolog 4 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:242,785,392...242,844,609
Ensembl chr 2:242,792,661...242,843,487 		JBrowse link
G Msh5 mutS homolog 5 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr20:3,773,867...3,793,337
Ensembl chr20:3,776,942...3,793,336 		JBrowse link
G Msh6 mutS homolog 6 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 6:6,562,631...6,579,995
Ensembl chr 6:6,562,632...6,579,956 		JBrowse link
G Pms1 PMS1 homolog 1, mismatch repair system component enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 9:48,229,403...48,340,237
Ensembl chr 9:48,253,410...48,340,237 		JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr12:10,676,818...10,701,161
Ensembl chr12:10,676,764...10,701,066 		JBrowse link
G Rad51 RAD51 recombinase enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:106,099,753...106,125,038
Ensembl chr 3:106,100,381...106,125,035 		JBrowse link
G Rad51b RAD51 paralog B enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 6:98,096,525...98,640,988
Ensembl chr 6:98,098,868...98,640,979 		JBrowse link
G Rad51c RAD51 paralog C enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:72,205,032...72,231,643
Ensembl chr10:72,205,032...72,231,248 		JBrowse link
G Rad51d RAD51 paralog D enables ISO (PMID:16717288) RGD PMID:16717288 NCBI chr10:67,805,720...67,824,452
Ensembl chr10:67,740,712...67,824,434 		JBrowse link
G Xrcc2 X-ray repair cross complementing 2 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:9,423,873...9,502,980
Ensembl chr 4:9,423,898...9,442,482 		JBrowse link
G Xrcc3 X-ray repair cross complementing 3 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 6:130,863,405...130,873,765
Ensembl chr 6:130,863,959...130,872,444 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20890
    small molecule sensor activity 39
      DNA damage sensor activity 18
        ATP-dependent DNA damage sensor activity 15
paths to the root