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ONTOLOGY REPORT - ANNOTATIONS

Term:ATP-dependent protein disaggregase activity
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Accession:GO:0140545 term browser browse the term
Definition:An ATP-dependent molecular chaperone activity that mediates the solubilization of ordered protein aggregates.
Synonyms:broad_synonym: protein disaggregase activity;   protein unfoldase activity


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ATP-dependent protein disaggregase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clpb ClpB family mitochondrial disaggregase enables ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:32573439), (PMID:34115842)		 UniProt
Ensembl
RGD		 PMID:32573439 PMID:34115842 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:156,028,740...156,158,183
Ensembl chr 1:156,028,930...156,168,788 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A enables ISO (PMID:23921388) RGD PMID:23921388 NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B enables ISO (PMID:23921388) RGD PMID:23921388 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 enables ISO (PMID:23921388) RGD PMID:23921388 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259 		JBrowse link
G Nsf N-ethylmaleimide sensitive factor, vesicle fusing ATPase enables ISS GO_REF:0000024 ParkinsonsUK-UCL GO_REF:0000024 NCBI chr10:88,727,912...88,857,375
Ensembl chr10:88,727,912...88,857,386 		JBrowse link
Term paths to the root
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Term Annotations click to browse term
  molecular_function 20634
    protein-containing complex destabilizing activity 12
      ATP-dependent protein disaggregase activity 5
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