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Term:membrane curvature sensor activity
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Accession:GO:0140090 term browser browse the term
Definition:Preferential binding of proteins on curved membranes. The binding to curved membranes by insertion (aka wedging) to curved membranes is mediated by both the hydrophobic and hydrophilic faces of the helix of membrane curvature sensing (MCS) proteins.

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membrane curvature sensor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arfip2 ADP-ribosylation factor interacting protein 2 enables ISO (PMID:29768204) RGD PMID:29768204 NCBI chr 1:159,974,255...159,980,398
Ensembl chr 1:159,974,201...159,980,336
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G Ica1 islet cell autoantigen 1 enables ISO (PMID:29768204) RGD PMID:29768204 NCBI chr 4:36,656,475...36,804,705
Ensembl chr 4:36,656,475...36,804,298
JBrowse link
G Pick1 protein interacting with PRKCA 1 enables ISO
PMID:29768204 GO_REF:0000107 NCBI chr 7:110,796,623...110,816,850
Ensembl chr 7:110,797,117...110,816,848
JBrowse link

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  molecular_function 19437
    binding 16664
      lipid binding 802
        membrane curvature sensor activity 3
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