4-hydroxysphinganine ceramide fatty acyl 2-hydroxylase activity - Ontology Report

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Term:	4-hydroxysphinganine ceramide fatty acyl 2-hydroxylase activity	go back to main search page
Accession:	GO:0120521	browse the term
Definition:	Catalysis of the reaction: an N-(1,2 saturated acyl)-(4R)-hydroxysphinganine + 2 Fe(II)-[cytochrome b5] + 2 H+ + O2 = an N-(2R-hydroxyacyl)-4R-hydroxysphinganine + 2 Fe(III)-[cytochrome b5] + H2O.
Synonyms:	xref:	MetaCyc:RXN3O-4042; RHEA:46520

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Genes (1)

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Fa2h

fatty acid 2-hydroxylase

enables

(PMID:22517924)
GO_REF:0000107

GO_REF:0000107

NCBI chr19:39,312,904...39,364,153
Ensembl chr19:39,312,906...39,364,153

Term paths to the root

Path 1
Term	Annotations
molecular_function	21100
catalytic activity	6213
oxidoreductase activity	868
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	244
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen	9
fatty acid 2-hydroxylase activity	1
4-hydroxysphinganine ceramide fatty acyl 2-hydroxylase activity	1

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